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01/11/2023

Share on PinterestOnions and garlic are rich in prebiotics, which could help improve gut health. Adam Nixon/StocksyPrebiotics, which are naturally found in plant-based foods, play a pivotal role in nurturing beneficial gut bacteria and supporting overall health.New research suggests that a high dose...

01/11/2023

A calorie is an amount of energy that a particular food provides. Consuming more calories than needed will result in weight gain, consuming too few will result in weight loss. How many calories a person should eat each day depends on a variety of factors, such as age, size, s*x, activity levels, and...

01/11/2023

Many myths surround pregnancy. In this article, we investigate 14 common pregnancy-related myths and explain the truth behind each of them.

01/11/2023

Just as people can have different sized breasts, hands, and feet, the depth of va**nas also varies. Learn about the average depth in this article.

01/11/2023

Experts have long said that phenylephrine is ineffective.

Concerns about the effectiveness of phenylephrine go back to 2007, according to CBS News. At that time, pharmacy professors Leslie Hendeles and Randy Hatton filed a petition to get the drug pulled from stores, because evidence indicated that it was no more effective than a placebo.
As NBC News further explained, the pharmacists cited studies that indicated that phenylephrine is metabolized in a way that only a small portion of the drug actually makes it to the nose in order to relieve congestion.

The FDA chose not to revoke the medicine's GRASE status in 2007, but Hendeles and Hatton submitted a new petition in 2015 requesting the agency pull the drug once again. The experts cited new data, adding to their claims that phenylephrine is "useless" at reaching the bloodstream through these oral OTC meds, CBS News reported.

"When you take it orally, it goes to the gut. And as it's being absorbed through the gut, there are two enzymes that metabolize it to such a great extent that essentially a very minuscule amount makes it into the bloodstream," Hatton told CBS News.

01/11/2023

The FDA is now investigating this ingredient.

Phenylephrine was first approved by the FDA for over-the-counter use in the 1970s, according to NBC News. But now, the agency's Nonprescription Drugs Advisory Committee (NDAC) is reevaluating the medication's effectiveness.

The two-day advisory meeting began yesterday, Sept. 11, and the committee is discussing new data concerning the "generally recognized as safe and effective" (GRASE) status of oral phenylephrine as a nasal decongestant, according to a briefing document posted by the FDA.

After reviewing the available data, the NDAC will vote on whether they believe the evidence shows that oral phenylephrine is effective or not. If the panel of outside advisers determine that the ingredient is ineffective, the FDA will then need to decide if it should be reclassified as not GRASE.

28/10/2023

Many common cold medications contain phenylephrine.

If you've ever suffered from a cold, allergies, or hay fever, chances are you've taken phenylephrine. Used to relieve nasal discomfort, sinus congestion, and pressure, this ingredient is found in many different decongestants, both on its own and in combination with other medications, according to the U.S. National Library of Medicine's MedlinePlus.

Sudafed PE is the most recognizable brand name for phenylephrine on its own. But the ingredient is also used in combination with other symptom relievers in many common cold medications.

Per MedlinePlus, you can find phenylephrine in Advil Congestion Relief; Alka-Seltzer Plus Cold and Cough Formula; Benadryl-D Allergy Plus Sinus; Children's Mucinex Multi-Symptom Cold; Robitussin Night Time Cough, Cold, and Flu; Tylenol Cold Multi-Symptom Nighttime; Vicks DayQuil Cold and Flu Relief; and Vicks NyQuil Sinex Nighttime Sinus Relief.

It's worth noting that the active ingredient in Sudafed—the kind pharmacists keep behind the counter, without the "PE" in its name—is pseudoephedrine, a proven decongestant. Medication with pseudoephedrine is not being reviewed by the FDA.

28/10/2023

Benzoyl peroxide treatments

Skincare enthusiasts, take note! If your products contain benzoyl peroxide, Gandhi says it's best not to keep them in the bathroom medicine cabinet. This includes many popular acne-fighting products, such as cleanser, toner, and spot treatments.

In fact, if you're a true skincare product devotee, you might want to invest in a mini-fridge that's dedicated solely to your serums and scrubs—just like actor Ana de Armas, whose glowing complexion is recommendation enough for us.

27/10/2023

Vitamins and supplements

Just like your OTC and prescription medications, vitamins and supplements won't hold up under the steamy conditions in your bathroom. Vitamin C, in particular, is susceptible to fluctuating temperatures and moisture, says Shaili Gandhi, PharmD and Vice President of Pharmacy at SingleCare.
"Medicine cabinets are not an ideal place to store medications, as bathrooms are often warm and humid rooms," she says, echoing Butler. "This type of environment may change medication and cause it to be less effective."

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