Report International

Report International Tuberculosis is a significant infectious cause of mortality and morbidity. Research is needed to identify biomarkers and measure efficacy of new tools.

Regional Prospective Observational Research in Tuberculosis International supports this global work.

Antimicrobial stewardship (AMS) focuses on the evidence-based and responsible use of anti-infective agents to improve pa...
01/16/2026

Antimicrobial stewardship (AMS) focuses on the evidence-based and responsible use of anti-infective agents to improve patient outcomes and limit resistance. Recent work highlights how TB is increasingly being incorporated into AMS models, supporting more coordinated, data-driven approaches to TB treatment and programmatic decision-making.

Read more: https://medicalxpress.com/news/2026-01-clinical-standards-antimicrobial-stewardship-tuberculosis.html

Antimicrobial stewardship (AMS) refers to coordinated strategies for the targeted, evidence-based, and safe use of anti-infective agents. The aim is to improve treatment outcomes, minimize side effects, and prevent the development and spread of antimicrobial resistance. While AMS is well established...

New findings provide additional evidence that treating tuberculosis with multiple drugs can more effectively inhibit Myc...
01/14/2026

New findings provide additional evidence that treating tuberculosis with multiple drugs can more effectively inhibit Mycobacterium tuberculosis, including drug-resistant strains. By targeting bacteria through complementary mechanisms, combination regimens remain central to overcoming resistance and improving treatment outcomes.

Learn more: https://www.rockefeller.edu/news/38777-this-new-one-two-punch-could-knock-out-drug-resistant-tb/

Tuberculosis is both curable and preventable, yet each year, it still kills more people than any other infectious disease. One reason is that current treatments hinge on rifampicin, an antibiotic that blocks bacterial transcription and forms the cornerstone of a multidrug regimen—and rising drug r...

New research demonstrates how an AI-based tool can support faster and more accurate detection of tuberculosis in childre...
01/12/2026

New research demonstrates how an AI-based tool can support faster and more accurate detection of tuberculosis in children, a population in which diagnosis remains particularly challenging. By improving interpretation of complex clinical and imaging data, this approach shows promise for earlier diagnosis and more timely initiation of treatment.

Read more: https://innovationdistrict.childrensnational.org/ai-tool-shows-promise-for-faster-more-accurate-pediatric-tuberculosis-detection/

(2 min. read)

From all of us at RePORT International, Happy Holidays!
12/24/2025

From all of us at RePORT International, Happy Holidays!

Get the latest updates from our December Newsletter, including key takeaways from our Leadership Meeting at Union Meetin...
12/16/2025

Get the latest updates from our December Newsletter, including key takeaways from our Leadership Meeting at Union Meeting and informative content on TB. Click here to read more:https://reportinternational.org/wp-content/uploads/2025/12/RePORT-December-2025-Newsletter-2.pdf

Check out our November Newsletter here: https://reportinternational.org/wp-content/uploads/2025/11/RePORT-November-2025-...
11/28/2025

Check out our November Newsletter here:https://reportinternational.org/wp-content/uploads/2025/11/RePORT-November-2025-Newsletter.pdf

Important diagnostic news for the TB community: Cepheid has announced that the World Health Organization (WHO) has prequ...
11/24/2025

Important diagnostic news for the TB community: Cepheid has announced that the World Health Organization (WHO) has prequalified the Xpert MTB/XDR test, a significant step forward for expanding access to rapid drug-resistance testing. This prequalification supports wider procurement and use of the assay, enabling countries to more effectively detect resistance to key TB drugs and strengthen clinical decision-making.

Read more: https://www.prnewswire.com/news-releases/cepheid-announces-world-health-organization-prequalification-of-the-xpert-mtbxdr-test-302595981.html

/PRNewswire/ -- Cepheid today announced that its Xpert® MTB/XDR test has been awarded prequalification status by the World Health Organization (WHO), marking a...

Why is tuberculosis still around when we already have a cure? NPR’s Shortwave podcast explores this question in a recent...
11/17/2025

Why is tuberculosis still around when we already have a cure? NPR’s Shortwave podcast explores this question in a recent episode, delving into the scientific, historical, and social factors that make TB one of the world’s most persistent infectious diseases. It’s an accessible and thought-provoking look at the intersection of medicine, inequality, and global health.

Take a listen: https://www.npr.org/2025/10/21/nx-s1-5552528/medical-history-science-tuberculosis-john-green

Tuberculosis – the world’s deadliest infectious disease – could be dormant in your system for years before you realize you have it. In the U.S., it’s relatively rare; provisional data shows that there were just over 10,000 cases in 2024. But in other parts of the world, especially lower-inco...

“If primary care doesn’t reach priority populations, it isn’t primary care.”In their recent The Lancet Regional Health c...
11/14/2025

“If primary care doesn’t reach priority populations, it isn’t primary care.”

In their recent The Lancet Regional Health commentary, Drs. Bruno Andrade and Beatriz Barreto Duarte call for a transformation in how primary care is delivered, emphasizing care that is person-centered, team-based, data-literate, and deeply connected to social protection.

Read the full commentary: https://www.thelancet.com/journals/lanprc/article/PIIS3050-5143(25)00067-6/fulltext

Primary care is the foundation of equitable health systems. It not only serves as the entry point to care but also ensures continuity of care over time and embraces a model of patient-centredness, delivering services that respond to individual needs and social realities. By doing so, primary care bu...

11/12/2025

RePORT Brazil’s Drs. Bruno Andrade and Mariana Araújo-Pereira have published an insightful essay exploring how immunology can illuminate human relationships. The essay draws parallels between cytokine communication and language.

Read more in Trends in Immunology: https://www.sciencedirect.com/science/article/pii/S1471490625002479

Climate change and tuberculosis are increasingly interconnected public health challenges.Climate change affects the diag...
11/10/2025

Climate change and tuberculosis are increasingly interconnected public health challenges.

Climate change affects the diagnosis, treatment, and transmission of TB through complex and overlapping pathways, as described in the WHO Framework on Climate Change and Health. A new analytical framework published in The Lancet Respiratory Medicine offers guidance for governments to better understand and address these interactions, supporting more resilient health systems in the face of environmental change.

Read the full article: https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00329-7/fulltext

Climate change is likely to exacerbate a range of determinants that drive tuberculosis, the world's leading cause of death from a single infectious agent. However, tuberculosis is often neglected in wider climate health discussions. Commissioned by WHO, we developed an analytical framework outlining...

Dr. Amita Gupta, RePORT India and RICC PI, co-chaired “Launch of TB and pregnancy consensus statement and call to action...
11/10/2025

Dr. Amita Gupta, RePORT India and RICC PI, co-chaired “Launch of TB and pregnancy consensus statement and call to action” on October 30. The consensus statement and call to action can be found at the following links:

Consensus Statement: Optimal and early inclusion of pregnant and lactating women in tuberculosis research
Call to Action: Accelerating research to end tuberculosis in pregnant and lactating women
https://www.who.int/publications/i/item/9789240112858

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