02/20/2026
Beware of Mixing Actives: The Risks of DIY Skincare Combos
https://youtube.com/shorts/h_3LyIZHpTw
Hello everyone. I’m Dr. Sam Speron, a board-certified plastic surgeon in The Chicago area.
When it comes to skincare, active ingredients aren’t something to play around with. Mixing powerful ingredients without guidance can lead to skin irritation, inflammation, and in some cases, even pigmentation issues. The risk? An overproduction of melanin that can leave dark spots behind, which are much harder to treat than they are to prevent.
Before layering on multiple actives, it’s best to consult with a skincare professional who can guide you on what’s safe for your unique skin type. Some combinations, like retinoids and exfoliating acids, or vitamin C and benzoyl peroxide, can actually do more harm than good if used together. I always remind patients, the right combination can make your skin thrive, but the wrong mix can lead to pigmentation and sensitivity.
Remember, skincare is highly personal, and what works for one person may not work for another. Don’t feel the need to chase trends or use every “miracle” ingredient at once. Instead, build a routine with balanced, compatible products that respect your skin’s needs for healthy, radiant results.
Dr. Sam Speron