Neuro-Behavioral Clinical Research

Neuro-Behavioral Clinical Research Neuro-Behavioral Clinical Research is a nationally recognized leader in CNS research, ranked among the top 10 facilities in the country.

NBR is dedicated to advancing mental health and memory loss treatment through cutting-edge clinical trials. Our building is located in North Canton and holds both clinical psychiatric practice and conducts clinical research trials in both the in-patient and out-patient facilities. If you are interested in participating in a clinical trial stop in and visit our building at any time.

Difficulty distinguishing what is real from what is not can be a challenging experience for individuals living with schi...
04/24/2026

Difficulty distinguishing what is real from what is not can be a challenging experience for individuals living with schizophrenia. Changes in perception or thought can make certain experiences feel very real, even when they do not match what others around them are seeing or hearing.

A person may describe experiences that seem confusing or out of place, react to things others do not perceive, or have difficulty trusting what is real in the moment. These situations can be unsettling, but they are not intentional. They reflect how schizophrenia affects the brain’s ability to process reality.

Understanding this experience can help create more supportive and calm responses. Offering reassurance, avoiding confrontation, and encouraging connection to care can make a meaningful difference.

If you, or a loved one, are living with schizophrenia, support and research opportunities are available.

Neuro-Behavioral Clinical Research is currently enrolling volunteers for a paid clinical trial focused on schizophrenia.
🔗 https://www.nbclinicalresearch.com/schizophrenia

Risk-taking behavior can be a sign of an elevated mood state in bipolar disorder. During these periods, a person may fee...
04/23/2026

Risk-taking behavior can be a sign of an elevated mood state in bipolar disorder. During these periods, a person may feel increased confidence, impulsivity, or a reduced sense of consequences, leading to decisions that are out of character.

Often, these changes are first noticed by loved ones. Spending patterns may shift, decisions may feel rushed, or behaviors may seem unusually bold or unrestrained. While it may appear as increased energy or confidence on the surface, it can also signal that the brain is entering a manic or hypomanic state.

These behaviors are not simply about poor judgment. They reflect how bipolar disorder can affect impulse control, decision-making, and risk awareness during mood episodes. Recognizing these early signs can help create an opportunity for support and intervention.

If you, or a loved one, are living with bipolar disorder, support and research opportunities are available.

Neuro-Behavioral Clinical Research is currently enrolling volunteers for a paid clinical trial focused on bipolar disorder.
🔗 https://www.nbclinicalresearch.com/bipolar

Fatigue is a common and often underestimated part of living with sickle cell disease. It can go beyond normal tiredness,...
04/22/2026

Fatigue is a common and often underestimated part of living with sickle cell disease. It can go beyond normal tiredness, affecting energy levels, focus, and the ability to keep up with everyday responsibilities.

This fatigue is linked to how sickle cell disease affects the body’s ability to carry oxygen efficiently. Over time, this can make even routine activities feel more physically and mentally demanding, especially during or after pain episodes.

Someone may need more rest, move more slowly, or have difficulty maintaining the same level of activity they once could. This is not a lack of effort. It reflects the ongoing strain the condition places on the body.

If you, or a loved one, are living with sickle cell disease, support and research opportunities are available.

Neuro-Behavioral Clinical Research is currently enrolling volunteers for a paid clinical trial focused on sickle cell disease.
🔗 https://www.nbclinicalresearch.com/sickle-cell

Anxiety does not always present as worry or fear. For many people, it shows up through physical symptoms that seem to ap...
04/21/2026

Anxiety does not always present as worry or fear. For many people, it shows up through physical symptoms that seem to appear without a clear cause. This can include headaches, muscle tension, stomach discomfort, fatigue, or a racing heart.

These symptoms are the result of the body’s stress response staying active for longer periods of time. Even when there is no immediate threat, the nervous system can remain on high alert, affecting how the body feels and functions throughout the day.

Someone may seem more physically uncomfortable, fatigued, or sensitive to stress without an obvious reason. Understanding that these symptoms can be connected to anxiety helps shift the focus toward support rather than confusion.

If you, or a loved one, are living with anxiety, support and research opportunities are available.

Neuro-Behavioral Clinical Research is currently enrolling volunteers for a paid clinical trial focused on anxiety.
🔗 https://www.nbclinicalresearch.com/anxiety

Difficulty following conversations is a common experience for individuals living with Alzheimer’s disease. Even familiar...
04/20/2026

Difficulty following conversations is a common experience for individuals living with Alzheimer’s disease. Even familiar discussions can become harder to process, as the brain has more difficulty keeping track of information, remembering what was just said, or finding the right response.

A person may lose their place in a conversation, ask for things to be repeated, or respond in ways that seem unrelated. These moments are not intentional. They reflect how Alzheimer’s affects memory, attention, and language processing in real time.

Loved ones may notice these changes during everyday interactions, especially in longer or more complex conversations. Creating a calm environment, speaking clearly, and allowing extra time can help make communication feel less overwhelming.

If you, or a loved one, are living with Alzheimer’s disease, support and research opportunities are available.

Neuro-Behavioral Clinical Research is currently enrolling volunteers for a paid clinical trial focused on Alzheimer’s disease.
🔗 https://www.nbclinicalresearch.com/alzheimers

Changes in energy can be one of the more noticeable signs of depression, especially when they begin to affect daily life...
04/17/2026

Changes in energy can be one of the more noticeable signs of depression, especially when they begin to affect daily life. Simple tasks like getting out of bed, completing routines, or staying focused throughout the day may start to feel overwhelming or take significantly more effort.

Often, these changes are first noticed by loved ones. A person may seem more fatigued, move more slowly, or have difficulty keeping up with responsibilities that once felt manageable. This shift in energy is not about a lack of motivation. It reflects how depression can impact both physical and mental functioning.

Understanding these changes can help reduce judgment and create space for support. Small adjustments, patience, and recognizing the effort it takes to complete even basic tasks can make a meaningful difference.

If you, or a loved one, are living with depression, support and research opportunities are available.

Neuro-Behavioral Clinical Research is currently enrolling volunteers for a paid clinical trial focused on depression.
🔗 https://www.nbclinicalresearch.com/depression

Changes in communication or thought patterns can be an early sign of schizophrenia. Someone may begin to have difficulty...
04/16/2026

Changes in communication or thought patterns can be an early sign of schizophrenia. Someone may begin to have difficulty organizing their thoughts, following conversations, or expressing ideas clearly. Speech may seem more disjointed, or responses may feel less connected to the topic at hand.

A person who was once easy to engage with may become harder to follow in conversation, pause more frequently, or express ideas in ways that feel confusing or unfamiliar. These shifts can happen gradually, making them easy to overlook at first.

These changes are not intentional. They reflect how schizophrenia can affect thinking, processing, and communication. Recognizing these patterns early can help create space for support, understanding, and timely care.

If you, or a loved one, are living with schizophrenia, support and research opportunities are available.

Neuro-Behavioral Clinical Research is currently enrolling volunteers for a paid clinical trial focused on schizophrenia.
🔗 https://www.nbclinicalresearch.com/schizophrenia

Increased irritability can be an early sign of a mood shift in bipolar disorder. It may appear as a shorter temper, frus...
04/15/2026

Increased irritability can be an early sign of a mood shift in bipolar disorder. It may appear as a shorter temper, frustration over small things, or feeling unusually on edge without a clear reason.

A person who is typically calm may seem more reactive, impatient, or easily overwhelmed. While irritability can be mistaken for stress or a bad day, it can also signal that the brain is beginning to shift before a more noticeable mood episode develops.

Recognizing these early patterns can help create an opportunity for support and early intervention. Paying attention to changes in mood, sleep, and behavior can play an important role in maintaining stability.

If you, or a loved one, are living with bipolar disorder, support and research opportunities are available.

Neuro-Behavioral Clinical Research is currently enrolling volunteers for a paid clinical trial focused on bipolar disorder.
🔗 https://www.nbclinicalresearch.com/bipolar

We’re proud to share that Dr. Shishuka Malhotra was recently featured in the April newsletter from the The STARR Coaliti...
04/14/2026

We’re proud to share that Dr. Shishuka Malhotra was recently featured in the April newsletter from the The STARR Coalition, an organization dedicated to advancing responsible clinical research.

This recognition highlights the compassionate, patient-first approach we bring to every study at Neuro-Behavioral Clinical Research.

Clinical trials don’t just move science forward—they create real opportunities for people to access new treatments and be part of something bigger.

Read the full feature here:
https://myemail.constantcontact.com/STARR-April-Newsletter---.html?soid=1126798118409&aid=nXNdGwQUoTE

Curious about participating in a study? Send us a message or visit our website to learn more.

Living with sickle cell disease often means facing pain that cannot be predicted. A person may feel stable one day and e...
04/14/2026

Living with sickle cell disease often means facing pain that cannot be predicted. A person may feel stable one day and experience a sudden pain crisis the next, making it difficult to plan, commit, or feel fully at ease.

This unpredictability can take a mental toll over time. The constant awareness that symptoms can change without warning may lead to anxiety, stress, and emotional fatigue. Even during periods without pain, there can be an underlying tension of not knowing when the next episode might occur.

Loved ones may notice the weight of this uncertainty in changes in mood, energy, or willingness to engage in activities. Understanding this experience can help shift the focus toward empathy, patience, and consistent support.

If you, or a loved one, are living with sickle cell disease, support and research opportunities are available.

Neuro-Behavioral Clinical Research is currently enrolling volunteers for a paid clinical trial focused on sickle cell disease.
🔗 https://www.nbclinicalresearch.com/sickle-cell

Over-planning and constant reassurance seeking can be subtle signs of anxiety, especially when they begin to affect dail...
04/13/2026

Over-planning and constant reassurance seeking can be subtle signs of anxiety, especially when they begin to affect daily life. Someone may feel the need to prepare for every possible outcome, ask repeated questions for confirmation, or struggle to feel settled even after receiving reassurance.

It may look like repeatedly checking details, needing frequent validation, or feeling unable to move forward without certainty. While it can appear like being overly cautious, it often reflects an underlying need to manage persistent worry or fear.

This cycle can provide temporary relief, but over time it can increase stress and make decision-making more difficult. Understanding the connection to anxiety can help shift the focus from frustration to support and more effective coping strategies.

If you, or a loved one, are living with anxiety, support and research opportunities are available.

Neuro-Behavioral Clinical Research is currently enrolling volunteers for a paid clinical trial focused on anxiety.
🔗 https://www.nbclinicalresearch.com/anxiety

Misplacing items in unusual places can be an early and often confusing sign of Alzheimer’s disease. Items may be left in...
04/10/2026

Misplacing items in unusual places can be an early and often confusing sign of Alzheimer’s disease. Items may be left in locations that do not make sense, such as placing keys in the refrigerator or a wallet in a drawer that is rarely used.

What may seem like simple forgetfulness can become more frequent or harder to explain over time. The person may not remember where the item was placed or may feel certain it was put somewhere else.

These changes are not intentional. They reflect how Alzheimer’s affects memory and the brain’s ability to track and organize everyday actions. Understanding this can help reduce frustration and encourage more patient, supportive responses.

If you, or a loved one, are living with Alzheimer’s disease, support and research opportunities are available.

Neuro-Behavioral Clinical Research is currently enrolling volunteers for a paid clinical trial focused on Alzheimer’s disease.
🔗 https://www.nbclinicalresearch.com/alzheimers

Address

5080 Aultman Avenue Northwest
North Canton, OH
44720

Opening Hours

Monday 8:30am - 5:30pm
Tuesday 8:30am - 5:30pm
Wednesday 8:30am - 5:30pm
Thursday 8:30am - 5:30pm
Friday 8:30am - 12pm

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+13304931118

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Our Story

Neuro-Behavioral Clinical Research strives for excellence by providing our patients the highest quality care available. Our studies are conducted with strict adherence to FDA and GCP guidelines to provide accurate data to our sponsors, while ensuring compassionate, ethical treatment of our patients.

We provide access to the most promising new medical and psychiatric treatment options and offer the highest quality care available. We are committed to pioneering new therapies to treat medical and psychiatric illnesses. We are committed to improving the lives of our patients, their caregivers and loved ones! As a participant in a clinical trial you'll receive excellent medical information, as well as the chance to help improve treatment for future generations. Trial participants help advance American Medicine. Without clinical trials no new treatment could be discovered and evaluated no proper safety testing would be possible, nor could you be assured of the effectiveness of current and future medical treatments. If you are interested in participating in a trial our specially qualified physicians and psychologists are ready to evaluate and determine whether clinical trials currently being conducted meet your needs. Participation in a trial is absolutely free of charge and help with transportation is available. If interested in learning more about our Clinical Trials please visit our website at www.nb-cr.com or call 330-493-1118 for more information.