Neuro-Behavioral Clinical Research

Neuro-Behavioral Clinical Research Neuro-Behavioral Clinical Research is a nationally recognized leader in CNS research, ranked among the top 10 facilities in the country.

NBR is dedicated to advancing mental health and memory loss treatment through cutting-edge clinical trials. Our building is located in North Canton and holds both clinical psychiatric practice and conducts clinical research trials in both the in-patient and out-patient facilities. If you are interested in participating in a clinical trial stop in and visit our building at any time.

Avoidance can be one of the quieter signs of anxiety, especially when it begins to replace everyday activities. Tasks th...
04/03/2026

Avoidance can be one of the quieter signs of anxiety, especially when it begins to replace everyday activities. Tasks that once felt routine like running errands, attending events, or even answering messages may start to feel overwhelming, leading someone to gradually pull back.

Often, these changes are first noticed by loved ones. It may look like canceling plans more frequently, hesitating to leave the house, or finding reasons to avoid situations that were once manageable. For the person experiencing anxiety, this avoidance can feel like temporary relief, but over time it can make daily life feel smaller and more restrictive.

Understanding this pattern can help shift the response from frustration to support. Gently encouraging small steps, maintaining routine, and recognizing the underlying anxiety can make a meaningful difference.

If you, or a loved one, are living with anxiety, support and research opportunities are available.

Neuro-Behavioral Clinical Research is currently enrolling volunteers for a paid clinical trial focused on anxiety.
đź”— https://www.nbclinicalresearch.com/anxiety

Repeating questions can be an early and often confusing sign of Alzheimer’s disease. A person may ask the same thing mul...
04/02/2026

Repeating questions can be an early and often confusing sign of Alzheimer’s disease. A person may ask the same thing multiple times, not realizing they have already received an answer. This is not intentional. It reflects changes in memory processing that make it difficult to retain recent information.

In many cases, loved ones are the first to notice this pattern. What may seem like forgetfulness at first can gradually become more frequent, especially in familiar conversations or daily routines. These moments can be frustrating for both the individual and those around them, but they are a result of how the disease affects short-term memory.

Understanding why repetition happens can help create more patient and supportive interactions. Responding calmly, maintaining routine, and offering reassurance can help reduce stress and confusion.

If you, or a loved one, are living with Alzheimer’s disease, support and research opportunities are available.

Neuro-Behavioral Clinical Research is currently enrolling volunteers for a paid clinical trial focused on Alzheimer’s disease.
đź”— https://www.nbclinicalresearch.com/alzheimers

Depression can change the way the brain experiences pleasure. Activities that once brought enjoyment such as hobbies, so...
03/31/2026

Depression can change the way the brain experiences pleasure. Activities that once brought enjoyment such as hobbies, social time, music, or favorite routines may begin to feel flat or uninteresting.

This symptom is known as anhedonia, a reduced ability to feel pleasure. Depression can affect brain systems involved in motivation and reward, making it harder to experience excitement, connection, or satisfaction from things that once felt meaningful.

For many people, this can be confusing and frustrating. Losing interest in things you used to love does not mean those things no longer matter to you. It reflects how depression can interfere with the brain’s ability to respond to positive experiences.

Recognizing anhedonia as a symptom of depression can help reduce self-blame and encourage seeking support.

If you are experiencing symptoms of depression, support and research opportunities are available.
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Neuro-Behavioral Clinical Research is currently enrolling volunteers for a paid clinical trial focused on depression.
đź”— https://www.nbclinicalresearch.com/depression

Sensory overload can be a challenging experience for individuals living with schizophrenia. Environments that are loud, ...
03/30/2026

Sensory overload can be a challenging experience for individuals living with schizophrenia. Environments that are loud, crowded, or filled with constant movement can overwhelm the brain’s ability to process information, making it harder to focus, communicate, or feel calm.

When the brain receives too much sensory input at once, it can increase stress and make symptoms more difficult to manage. Everyday situations like busy stores, crowded events, or noisy environments may become exhausting or disorienting, even when others around may not notice the intensity of the stimulation.

Recognizing the impact of sensory overload can help individuals and their support systems create calmer, more manageable environments. Simple adjustments like quieter spaces, predictable routines, and stepping away from overstimulating settings can help reduce stress and support stability.

If you or someone you care about is living with schizophrenia, support and research opportunities are available.
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Neuro-Behavioral Clinical Research is currently enrolling volunteers for a paid clinical trial focused on schizophrenia.
đź”— https://www.nbclinicalresearch.com/schizophrenia

I’m honored to have Neuro-Behavioral Clinical Research featured in the International Business Times.When I founded NBCR,...
03/27/2026

I’m honored to have Neuro-Behavioral Clinical Research featured in the International Business Times.

When I founded NBCR, the goal was simple but deeply important: to advance mental health care through research that is both scientifically rigorous and deeply compassionate toward the people we serve.

Mental health conditions affect millions of individuals and families. Clinical research plays a critical role in discovering new treatments and expanding options for patients who are still searching for relief.

Every study we conduct represents more than data—it represents hope, progress, and the possibility of improving lives.

I’m incredibly grateful to our dedicated team, our research partners, and the participants who make this work possible.

If you’re interested in learning more about our mission and the work we’re doing, I invite you to read the full article.

Shishuka Malhotra

https://www.ibtimes.com/neuro-behavioral-clinical-research-advancing-mental-health-through-compassionate-science-3793242

After a mood episode in bipolar disorder, many people experience a period of mental and physical exhaustion. Even once s...
03/27/2026

After a mood episode in bipolar disorder, many people experience a period of mental and physical exhaustion. Even once symptoms begin to stabilize, the brain and body often need time to recover from the intensity of the episode.

This recovery period can include fatigue, slower thinking, difficulty concentrating, or a sense of emotional heaviness. Some individuals may also experience feelings of embarrassment, guilt, or frustration when reflecting on what happened during the episode. These reactions are common and reflect the strain that mood episodes can place on both emotional and cognitive systems.

Understanding that recovery takes time can help reduce self-criticism and allow space for rest and support. Stabilization is not just about ending an episode, but also about giving the brain the time it needs to regain balance.

If you are living with bipolar disorder, support and research opportunities are available.
- - - - -
Neuro-Behavioral Clinical Research is currently enrolling volunteers for a paid clinical trial focused on bipolar disorder.
đź”— https://www.nbclinicalresearch.com/bipolar

Living with sickle cell disease often means navigating life between hospital visits. Even during periods when symptoms a...
03/26/2026

Living with sickle cell disease often means navigating life between hospital visits. Even during periods when symptoms are quieter, the possibility of a pain crisis or medical complication can create ongoing stress and uncertainty.

Frequent medical care can interrupt work, school, and daily routines, making it difficult to plan ahead or maintain consistency. This unpredictability can also affect mental health, leading to anxiety, fatigue, and the emotional strain of always preparing for the next potential flare-up.

Recognizing the challenges of living between hospital visits helps highlight the full impact of sickle cell disease beyond physical symptoms. Support, understanding, and continued medical research are important in improving both quality of life and long-term care.

If you are living with sickle cell disease, support and research opportunities are available.
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Neuro-Behavioral Clinical Research is currently enrolling volunteers for a paid clinical trial focused on sickle cell disease.
đź”— https://www.nbclinicalresearch.com/sicklecell

Anxiety does not always look like fear or worry. For many people, it shows up as irritability, frustration, or a short t...
03/25/2026

Anxiety does not always look like fear or worry. For many people, it shows up as irritability, frustration, or a short temper that seems to appear without a clear reason.

When the brain is constantly on alert, the nervous system stays in a heightened state of stress. This can make everyday situations feel overwhelming and reduce patience for small disruptions. As a result, anxiety may appear as agitation, restlessness, or feeling easily annoyed, even when someone does not immediately recognize anxiety as the cause.

Understanding that irritability can be a symptom of anxiety helps reduce self-criticism and confusion. Recognizing these patterns is an important step toward addressing the underlying stress and finding healthier ways to manage it.

If anxiety is affecting your daily life, support and research opportunities are available.
- - - - -
Neuro-Behavioral Clinical Research is currently enrolling volunteers for a paid clinical trial focused on anxiety.
đź”— https://www.nbclinicalresearch.com/anxiety

In the early stages of Alzheimer’s disease, communication may begin to change in subtle ways. One common experience is d...
03/24/2026

In the early stages of Alzheimer’s disease, communication may begin to change in subtle ways. One common experience is difficulty finding the right word during conversation. A person may pause more often, substitute a different word, or describe an object instead of naming it directly.

These changes happen because Alzheimer’s can affect the areas of the brain responsible for language and memory retrieval. The words are still there, but accessing them becomes more difficult. This can feel frustrating for the person experiencing it and confusing for those around them.

Understanding that word-finding difficulty is a symptom of the disease can help create more patient and supportive conversations. Giving extra time to speak, reducing pressure during discussions, and maintaining a calm environment can make communication feel less stressful.

If you are living with Alzheimer’s disease, support and research opportunities are available.
- - - - -
Neuro-Behavioral Clinical Research is currently enrolling volunteers for a paid clinical trial focused on Alzheimer’s disease.
đź”— https://www.nbclinicalresearch.com/alzheimers

Depression is often associated with sadness, but many people experience something different. Instead of overwhelming emo...
03/23/2026

Depression is often associated with sadness, but many people experience something different. Instead of overwhelming emotion, they may feel an “emotional flatline,” a sense of numbness where joy, excitement, and connection seem distant or absent.

Activities that once felt meaningful may no longer bring the same sense of interest or satisfaction. Conversations can feel harder to engage in, and even positive events may not create the emotional response someone expects. This experience is known as emotional numbness, and it is a common symptom of depression.

Understanding this side of depression can help reduce confusion and self-blame. Feeling disconnected from emotions does not mean someone does not care. It reflects how depression can affect the brain’s ability to process pleasure and connection.

If you are experiencing symptoms of depression, support and research opportunities are available.
- - - - -
Neuro-Behavioral Clinical Research is currently enrolling volunteers for a paid clinical trial focused on depression.
đź”— https://www.nbclinicalresearch.com/depression

Recovery from schizophrenia often involves more than managing symptoms with medication. Rebuilding social confidence can...
03/20/2026

Recovery from schizophrenia often involves more than managing symptoms with medication. Rebuilding social confidence can be an important part of long-term stability and overall well-being.

Schizophrenia can affect communication, social interaction, and confidence in everyday situations. Over time, this may lead to withdrawal or hesitation in social settings. Gradually rebuilding these skills through supportive environments, therapy, and meaningful connections can help individuals regain a sense of comfort and independence.

Strengthening social confidence supports more than relationships. It can improve daily functioning, increase opportunities for engagement, and help individuals feel more connected to their communities.

If you or someone you care about is living with schizophrenia, support and research opportunities are available.
- - - - -
Neuro-Behavioral Clinical Research is currently enrolling volunteers for a paid clinical trial focused on schizophrenia.
đź”— https://www.nbclinicalresearch.com/schizophrenia

Mood episodes in bipolar disorder often do not begin suddenly. In many cases, subtle changes appear first, offering earl...
03/19/2026

Mood episodes in bipolar disorder often do not begin suddenly. In many cases, subtle changes appear first, offering early clues that a shift may be developing.

These changes can include differences in sleep patterns, energy levels, concentration, or daily routines. Someone may notice needing less sleep, feeling unusually restless, having racing thoughts, or experiencing a drop in motivation and energy. While these signs may seem small at first, they can sometimes signal the beginning of a larger mood change.

Recognizing these early patterns can make a meaningful difference. Paying attention to sleep, stress levels, and behavior changes can help individuals and care teams respond earlier and take steps to support stability.

If you are living with bipolar disorder, support and research opportunities are available.
- - - - -
Neuro-Behavioral Clinical Research is currently enrolling volunteers for a paid clinical trial focused on bipolar disorder.
đź”— https://www.nbclinicalresearch.com/bipolar

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5080 Aultman Avenue Northwest
North Canton, OH
44720

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Our Story

Neuro-Behavioral Clinical Research strives for excellence by providing our patients the highest quality care available. Our studies are conducted with strict adherence to FDA and GCP guidelines to provide accurate data to our sponsors, while ensuring compassionate, ethical treatment of our patients.

We provide access to the most promising new medical and psychiatric treatment options and offer the highest quality care available. We are committed to pioneering new therapies to treat medical and psychiatric illnesses. We are committed to improving the lives of our patients, their caregivers and loved ones! As a participant in a clinical trial you'll receive excellent medical information, as well as the chance to help improve treatment for future generations. Trial participants help advance American Medicine. Without clinical trials no new treatment could be discovered and evaluated no proper safety testing would be possible, nor could you be assured of the effectiveness of current and future medical treatments. If you are interested in participating in a trial our specially qualified physicians and psychologists are ready to evaluate and determine whether clinical trials currently being conducted meet your needs. Participation in a trial is absolutely free of charge and help with transportation is available. If interested in learning more about our Clinical Trials please visit our website at www.nb-cr.com or call 330-493-1118 for more information.