OpenCures

12/28/2025

What is the construction of the blueprints for the oldest humans like?

In brief, Santos-Pujol and colleagues characterize the multiomics landscape of the human with the most extreme longevity. The study enables the association of advantageous genetic variants, an engaged lipid metabolism, low inflammation levels, a proficient immune system, a rejuvenated microbiome com...

09/23/2025

This is what is necessary for AI to be truly useful for health!

A recording from Eric Topol's live video

06/20/2025

There is a deep dissatisfaction of customers with the research-medical industry. Thankfully the tools are being developed that empower individuals beyond anything that industry would like and we will soon be able to take responsibility for the development of our own health solutions. Hope you might hear some interesting or at least novel perspectives in this podcast.

What if aging wasn’t inevitable? What if you could take charge of your health data and help accelerate life-saving breakthroughs? In this week’s episode, I sit down with Dr. Kevin Perrott — cancer survivor, PhD in biological sciences, and CEO of OpenCures — to explore how data ownership, AI,...

12/12/2024

Justin Loew, Director of one of our earliest collaborators and supporters, Longecity, (nee the Immortality Institute) interviewed me about OpenCures and other questions. Very much enjoyed interacting with someone with the depth of experience he has. His perspective is definitely worth hearing as well.

Pioneers in life extension research & advocacy interviewed by the Longecity.org community forum.

12/10/2024

You should go like your life depended on it.

April 4 - May 29, 2025. Berkely, California. Vitalist Bay is an 8-week longevity zone bringing the world’s best minds together to extend human healthspan & solve aging.

07/27/2024

Now it all makes sense... maybe not all, but these 3D models are *incredible*.

Discover the most advanced and accurate 3D model of the human anatomy available. Developed by a team of over 30 expert 3D artists and medical professionals, this model is the result of 8 years of hard work and dedication.

07/12/2024

I have no words. Welcome to the future.

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07/09/2024

The Five Stages of AI Grief.
Excellent article.
https://www.noemamag.com/the-five-stages-of-ai-grief/?

07/09/2024

We all need a 'better angel'.. or perhaps we might call it a 'gentle nag', but regardless, being reminded we need to do what's good for us PERSONALLY by our own dedicated "better angel" is coming.

I hope there is a plan to harvest the data of the effects occurring in the health of people making behavior changes and we will be looking for opportunities to work with this and other services.

Making healthier choices is hard. But it’s also something that AI is uniquely positioned to solve, write Sam Altman and Arianna Huffington.

07/04/2024

MODEST?! I'd call the results pathetic. . just today I heard on the news of yet another Alzheimer's drug coming on the market that... WOW... delays cognitive decline by a whole SEVEN MONTHS!... break out the champagne!!! I'm pretty sure they didn't test the effectiveness of their very expensive pharmaceutical against free lifestyle changes... also they are targeting the downstream and non-causal accumulation of B-amyloid which explains why they could only squeeze a few months. How about prescribing exercise and giving them a discount on their premiums? People just can't seem to do things that are good for them if they go against their physical appetites and they don't have a HUGE reason to push against it.. maybe money could be that reason.

Kisunla is not a cure and slows worsening memory and cognitive problems by about seven months.

07/04/2024

Not long ago some studies out of Stanford showed that there really is no "safe" level of alcohol consumption and that drinking alcohol is more like smoking with any amount being damaging. If we can't understand how we can psychologically make decisions that deliberately harm our health in exchange for an altered state of consciousness and/or the dopamine that we get in exchange, we will never be able to modify these behaviors which are detrimental. Here's another recent story on how drinking accelerates aging, but given what we know about how drinkers and non-drinkers 'look' as they age, I don't know why it needed a study.

Alcohol dependence accelerates biological aging, as measured by epigenetic clocks, but a three-week treatment program can significantly decelerate this process and improve biomarkers associated with aging.

06/07/2024

What an awesome chance to hang with some sane people.

When I first met Jasmine and the team at Rejuve.AI and we started discussing working together and the barriers to progress to the development of interventions to maintain and restore function for aging humans, it became clear that the science and technology were there to be discovered, and more clear that "we are the cavalry" we've been waiting for. As Michael J. Fox has said, "There is no Department of Cures, the department is us.". Thrilled to have this seed and will be tending to it carefully help it grow, exponentially. Maybe there are some of you out there who want to align vectors and aim them at the heart of "The Dragon-Tyrant"?

https://www.rejuve.ai/post/rejuve-ai-opencures-partnership

Discover the new partnership between Rejuve.AI and OpenCures, revolutionizing the wellness ecosystem. Get insights from Dr. Kevin Perrott on the latest developments in health technology and the quest for longevity.