Buck Institute for Research on Aging

02/04/2026

Another full house at the Buck today for our monthly community seminar. Today’s seminar is about Advancements in the Prevention of Cognitive Decline with Buck Professor, Lisa Ellerby, PhD. As we get older, many people face brain-related diseases like Alzheimer’s and Parkinson’s which can seriously affect memory, movement, and overall quality of life. Dr. Ellerby is working to uncover what causes these conditions as we age—and more importantly, how to stop them. Using cutting-edge tools like stem cells made from patient samples, genetic analysis, and even gene editing (like CRISPR), she’s digging deep to understand what goes wrong in the brain and finding new ways to treat or prevent these diseases. Register for our next seminar on March 4 with our CEO Eric Verdín, MD. Registration opens today at noon on our website under events.

02/04/2026

NEW BUCK PODCAST EPISODE dropped today! In this episode, Eric Verdin, CEO of the Buck Institute, and Stanford University’s Dr. Tony Wyss-Coray discuss the groundbreaking science of brain rejuvenation through heterochronic parabiosis, a process where young blood factors are shown to restore cognitive function and potentially extend lifespan. Moving from the lab to the clinic, they explore the next frontier: Proteomic Clocks. By measuring thousands of proteins, scientists can now determine the biological age of individual organs, allowing for the detection of Alzheimer’s and other neurodegenerative diseases up to 15 years before symptoms appear. This shift toward high-precision organ tracking marks a new era in preventative geroscience and personalized longevity.

01/30/2026

At the Buck, our breakthroughs are powered by people. Faces of Discovery, a monthly installment to the Buck Blog, introduces the scientists unraveling the mysteries of aging and pioneering ways to help us all live better longer.

This month we're featuring Taylor Valentino PhD., a Postdoctoral Researcher in the Winer lab. He studies how diet and exercise effect the immune system during aging. Read more about his research, how he got to where he is today and where he's hoping to take his research in the future.

A new monthly installment to the Buck Blog, introducing the scientists unraveling the mysteries of aging and pioneering ways to help us all live better longer

01/28/2026

Congrats to the Buck’s Tracy lab for their new paper in Molecular Neurodegeneration. The work describes a new mechanism for how synapses deteriorate in disease and related dementias. The research shows that tau oligomers trigger progressive synapse decline and deterioration in human iPSC-derived neurons. The team developed a new tool that maps dynamic postsynaptic changes after acute tau oligomer exposure; technology that was combined with electrophysiology and monitoring of synaptic structures over time. The team found a cascade of events caused by tau oligomers that drive synapse fate toward either functional impairment or loss. We’re proud of the work. Read our news release here:

Congrats to the Buck’s Tracy lab for their new paper in Molecular Neurodegeneration. The work describes a new mechanism for how synapses deteriorate in Alzheimer's disease and related dementias.

01/28/2026

Friday was a very special day at Buck as we celebrated the installation of Paul F. Glenn’s bust in our atrium—an honor made possible by our longstanding partnership with the Glenn Foundation and its CEO Leonard Judson. We’re deeply grateful for their vision and support, and for the inspiring words shared by Mary McEachron on the history of the Buck, along with Paul Glenn’s instrumental role in it. Thank you, Paul!

01/21/2026

The new season of the Buck podcast “We’re not getting any younger…yet” launched TODAY! We’re excited that our first episode features Harvard geneticist George Church, one of the most provocative thinkers in the longevity field.

It’s available wherever you get your podcasts. Be sure to subscribe so you don’t miss a single episode! and SHARE!

01/20/2026

The new season of the Buck podcast “We’re not getting any younger…yet” launches tomorrow! We’re excited that our first episode will feature Harvard geneticist George Church, one of the most provocative thinkers in the longevity field.

Look out for the pod tomorrow, Wednesday January 21!

It’s available wherever you get your podcasts. Be sure to subscribe so you don’t miss a single episode!

01/15/2026

Season 3 of the Buck Podcast, “We’re not getting any younger…yet” launches today!!! Listen to the trailer today! First episode is next Wednesday.

Our new co-hosts, Buck CEO Eric Verdin and Buck Clinical Researcher Brianna Stubbs, are chatting with the brightest minds on the planet about how you can live better longer!

Listen on Spotify, Apple Podcasts, or wherever you get your podcasts and make sure to subscribe so you don’t miss a single episode!

Podcast sponsored by Ashton Thomas Private Wealth

01/14/2026

New research in Aging Cell highlights spaceflight as a unique model for studying aging as well as cellular resilience. The Furman lab helps set the stage for testing potential anti-aging interventions for those of us firmly planted on planet Earth.

New research in Aging Cell highlights spaceflight as a unique model for studying aging as well as cellular resilience. The Furman lab helps set the stage for testing potential anti-aging interventions for those of us firmly planted on planet Earth.

01/13/2026

We are excited to share that season 3 of the Buck podcast “We’re not getting any younger…yet” is ready for launch!

Our new co-hosts, Buck CEO Eric Verdin and Buck Clinical Researcher Brianna Stubbs, will be chatting with the brightest minds on the planet about how you can live better longer!

Look out for our Season 3 trailer on Wednesday January 14 and our first episode dropping January 21.

Listen on Spotify, Apple Podcasts, or wherever you get your podcasts and make sure to subscribe so you don’t miss a single episode!

Podcast sponsored by Ashton Thomas Private Wealth

01/12/2026

On Friday we were pleased to host Ryo Sanabria, Assistant Professor from USC who gave an FRS talk on his lab’s exciting work on actin and how it is much more than a loading control!

01/07/2026

We have a few more spots for a clinical trial at Buck focused on post-menopausal women. Eligible participants will receive up to $210 in compensation. Note: Participants must be between 45-65 years old, non-diabetic and not currently on GLP-1s or HRTs. Email GRACE-study@buckinstitute.org if interested.