Inspired Wellness, PLLC

02/23/2026

You finally sit down. But instead of relief - there’s anxiety. Your thoughts race. You want to fidget or just get up and be productive.

Resting can cause anxiety because it can make us feel what we’ve buried.
If we learned early on that being productive was the way to stay safe as a child - it can cause anxiety.

At the end of the day - having a hard time relaxing is a pattern of stored trauma in the body.

Anybody here recognize that pattern in themselves?

02/23/2026

02/23/2026

B12 + Folate + B6: are the methylation triad 🧬🫀🧠

When one is low, the entire pathway can bottleneck.

These three B-vitamins work as a tightly linked system that drives one-carbon metabolism, the biochemical process behind DNA synthesis, red blood cell production, neurotransmitter balance, and homocysteine regulation.

That’s why B12, folate, and B6 are often discussed together, not as isolated nutrients, but as a functional triad supporting cardiovascular, neurological, and metabolic health.

Why this combo matters
• Supports healthy homocysteine metabolism (a cardiovascular risk marker)
• Required for DNA synthesis and repair
• Supports red blood cell formation (distinct from iron)
• Plays a key role in nerve function and energy metabolism

RDAs vs real-world needs ⚖️

RDAs are designed to prevent overt deficiency in the general population, not necessarily to optimize function in people with:
• Elevated homocysteine
• Malabsorption issues
• Increased demand (pregnancy, aging, stress)
• Certain dietary patterns (low animal foods, restricted diets)

As a result, some individuals require supplemental doses above the RDA, under appropriate guidance.

Practical protocol:
Baseline intake (RDA level):
• Vitamin B12: 2.4 mcg/day
• Folate: 400 mcg DFE/day (600 mcg DFE during pregnancy)
• Vitamin B6: 1.3–1.7 mg/day

Common supplemental ranges used clinically (not required for everyone):
• B12: 25–500 mcg/day (higher doses often used for deficiency or absorption issues)
• Folate (B9): 400–800 mcg DFE/day
• B6: 5–25 mg/day

⚠️ Important considerations
• High folate intake can mask a B12 deficiency, especially in older adults
• B6 has an established upper limit. Chronic megadoses may not be appropriate
• These vitamins work best together, not in isolation

Who may benefit most
• Individuals with elevated homocysteine
• Older adults or those with reduced B12 absorption
• Pregnancy and pre-conception (folate is critical)
• People with fatigue, anemia, or confirmed deficiencies

02/23/2026

02/22/2026

✨ Did you know many women spend years trying to figure out perimenopause without the right support? I’m proud to be listed in the Perry Academy Perimenopause Directory — a trusted resource connecting women with clinicians who truly understand this stage of life. 📌

Whether you’re dealing with hot flashes, sleep issues, anxiety, or hormonal changes that just don’t make sense — there are answers and personalized care options.
Learn more + connect: 🔗 https://www.perimenopausedirectory.com/certified-providers-details?recordId=rec1wdUbrkdmMVLEk

02/18/2026

Women need to tend to their gut health even more as they approach menopause and after it in the postmenopausal period of their lives. Menopause-related estrogen decline reshapes the gut microbiome, reducing beneficial bacteria and increasing inflammation, intestinal permeability, and the risk of metabolic syndrome.

What's the takeaway? Personalized dietary patterns rich in fiber, polyphenols, and healthy fats, such as Mediterranean or plant-forward approaches, can help restore microbial balance and support metabolic health in postmenopausal women.

02/16/2026

02/16/2026

Your thoughts, mood, energy, motivation, sleep, and focus all depend on chemical signals moving between brain cells.

These are neurotransmitters. Each one plays a distinct role in how the brain regulates behavior, physiology, and perception.

Acetylcholine
Movement, memory, learning, attention

Dopamine
Motivation, reward processing, goal-directed behavior

Serotonin
Mood stability, appetite, sleep regulation

Norepinephrine
Alertness, attention, stress response

GABA
Primary inhibitory signal that reduces neural excitability and promotes calm

Glutamate
Primary excitatory signal essential for learning and memory

Histamine
Wakefulness and immune signaling

Glycine
Motor control and nervous system regulation

Endorphins
Pain modulation and natural reward

Substance P
Pain transmission and inflammatory signaling

Epinephrine
Fight-or-flight activation

Adenosine
Sleep pressure and neural recovery (antagonized by caffeine)

The broader point is simple: brain function is not just electrical. It is chemical communication in constant balance.

When neurotransmitter signaling is well regulated, it supports mood stability, cognitive performance, stress resilience, sleep quality, and motivation.
When signaling becomes dysregulated, functional symptoms often appear before structural disease.
Neurotransmitters are the language of the nervous system.

02/16/2026

02/11/2026

The brain consumes ~20% of the body’s energy (it can be up to 50% around the age of 10).

Its function, no surprise, depends on consistent metabolism and micronutrient availability

1️⃣ Homocysteine Metabolism
Vitamins B6, B9 (folate), B12, riboflavin, choline, and niacin (B3) regulate homocysteine, an amino acid that can damage blood vessels and neurons when elevated. Adequate folate and B12 reduce homocysteine levels, supporting long-term cognitive function.
🟢 Example: Supplementing B12 and folate in older adults with elevated homocysteine has been shown to slow brain atrophy and improve memory performance.

2️⃣ Energy Metabolism
The brain needs a constant ATP supply to sustain signaling and plasticity. B vitamins, lipoic acid, CoQ10, iron, and manganese act as cofactors in mitochondrial energy production. A deficiency in thiamine (B1) or riboflavin (B2) impairs energy metabolism and can contribute to fatigue, poor focus, or cognitive fog.
🟢 Example: Patients with thiamine deficiency often experience reversible confusion and energy loss once repleted with B1.

3️⃣ Neurotransmitter Synthesis and Binding
Vitamin B6 is required to convert amino acids into neurotransmitters such as serotonin, dopamine, and GABA. Low B6 disrupts these conversions and weakens mood regulation.
🟢 Example: B6 supplementation in individuals with low serotonin production improves emotional stability and stress resilience by restoring neurotransmitter balance.

4️⃣ Nerve Signal Transmission
Efficient signal propagation relies on nutrients that maintain myelin integrity and axonal firing. DHA, folate (B9), B12, thiamine, and iron are all critical for this process.
🟢 Example: Low B12 can lead to nerve demyelination and neuropathy, while DHA from omega-3s improves communication speed between neurons.

5️⃣ Membrane Integrity
Neuronal membranes are rich in fats that are easily oxidized. DHA, EPA, vitamins C and E, and polyphenols protect and stabilize these membranes.
🟢 Example: Vitamin E helps prevent oxidation of brain fats, and vitamin C regenerates vitamin E, maintaining optimal membrane fluidity and receptor function.

6️⃣ Neuron Growth and Development
Vitamin D, polyphenols, and flavonoids influence neuronal growth, repair, and plasticity.
🟢 Example: Vitamin D receptors in the hippocampus regulate genes tied to memory formation, while berry polyphenols increase brain-derived neurotrophic factor (BDNF), promoting neurogenesis.

7️⃣ Blood Flow and Oxygen Delivery
Polyphenols and flavonoids enhance vascular function and cerebral blood flow, ensuring that neurons receive adequate oxygen and nutrients.
🟢 Example: Cocoa flavanols and blueberry extracts have been shown to increase brain blood flow and improve cognitive performance in both young and older adults.

Brain performance relies on more than calories and oxygen. Micronutrients provide the molecular infrastructure for energy production, neurotransmission, protection, and plasticity. B vitamins fuel mitochondria, DHA and antioxidants preserve neuronal membranes, and polyphenols and vitamin D enhance repair and blood flow. The right micronutrients do not just protect the brain; they help it adapt, learn, and thrive.

02/10/2026

Skeletal muscle has two modes: signaling and silence. Modern life keeps people geared toward a silence state.

When muscles contract, they don’t just generate force. They release myokines, signaling molecules that communicate with the brain, immune system, liver, adipose tissue, and vasculature. When muscles remain inactive, that signaling largely shuts down.

The difference is biochemical, not motivational:

• Contracting muscle releases myokines into circulation
• These signals help regulate inflammation, metabolism, and stress responses
• Inactive muscle becomes metabolically quiet and chemically disengaged

This is why regular movement consistently lowers chronic inflammation, even without weight loss or major changes in fitness.

Same muscles. Same genome. Completely different signaling environment. Exercise doesn’t just build strength or burn calories. It determines whether skeletal muscle participates in whole-body communication (or remains silent).

02/10/2026

Bitly’s Connections Platform is more than a free URL shortener, with robust link management software, advanced QR Code features, and a landing page solution.