Lake Nona Impact Forum

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In this forward-looking conversation, Mike Sicilia, CEO of Oracle, joined Gloria Caulfield, Founder & Executive Director...
04/09/2026

In this forward-looking conversation, Mike Sicilia, CEO of Oracle, joined Gloria Caulfield, Founder & Executive Director of the Lake Nona Impact Forum, to discuss how cloud infrastructure, data, and AI are reshaping the systems behind healthcare.

“It’s not just about making the systems more efficient, to make the people more efficient. It’s about making the systems disappear…Once they trust it, I think 95% of the screens can just go away.” - Mike Sicilia

Some of the most interesting ideas come from unexpected intersections.In this compelling session, Frans Johansson, CEO o...
04/08/2026

Some of the most interesting ideas come from unexpected intersections.

In this compelling session, Frans Johansson, CEO of Medici Next, explored how innovation often happens when people from different fields come together and look at problems in new ways.

“Predictability is not the key to success. It’s unpredictability that helps us stand apart… this very human idea of connecting something unexpected.”

Three years ago on this stage, Peter Lee, PhD demonstrated something called Prometheus.“And what the audience didn't kno...
04/06/2026

Three years ago on this stage, Peter Lee, PhD demonstrated something called Prometheus.

“And what the audience didn't know, and what OpenAI, in our agreement, didn't tell people is that Prometheus was actually what we call GPT4." - Peter Lee, PhD

Moderated by Christina Farr, CEO & Editor-in-Chief of Second Opinion Media and General Partner, Scrub Capital, the conversation featured:

🔹 Peter Lee, PhD, President, Microsoft Research
🔹 Lorraine Bardeen, Corporate Vice President, AI Strategy & Transformation, Microsoft
🔹 Lerrel Pinto, PhD, Co-Founder & CEO, Assured Robot Intelligence (ARI); Assistant Professor, New York University

Joined also by ARI’s walking robot, the conversation returned to where AI is heading next.

“Well, I studied classical music since I was two, so I know a little about perfection – it’s unattainable.” Pianist, Com...
04/02/2026

“Well, I studied classical music since I was two, so I know a little about perfection – it’s unattainable.”

Pianist, Composer, & Activist Chloe Flower brought life and imagination in a forum of health and innovation through her music to the audience at the Lake Nona Impact Forum.

03/31/2026

As we come to the close of Endometriosis Awareness Month, it’s a reminder of how much we still don’t understand about the disease.

Louise King, JD, MD, Asst. Professor, Obstetrics, Gynecology & Reproductive Biology, Harvard Medical School; Director, Reproductive Bioethics, HMS Center for Bioethics, shared with us at LNIF26:

“I want someone to put me out of a job so that any patient with endometriosis doesn't need me as a surgeon anymore because we can fix it in a different way.”

She sees it every day, both as a surgeon and as a parent. There are treatments that show promise, but from both her clinical work and her experience as a parent, it’s clear we still need more research and a deeper understanding of the condition.

Sleep is finally getting the attention it deserves.At the Lake Nona Impact Forum, Michael Breus, PhD, Clinical Psycholog...
03/30/2026

Sleep is finally getting the attention it deserves.

At the Lake Nona Impact Forum, Michael Breus, PhD, Clinical Psychologist, Board-Certified Sleep Specialist, and known to many as The Sleep Doctor, joined by Dawn Mussallem, DO, DipABLM, Global Chief Medical Officer at Fountain Life and former Double Board-Certified Mayo Clinic Physician, discussed what current research is revealing about rest.

Better sleep supports clearer thinking, stronger performance, and long-term health.

“I think it’s going to be humans at the center, empowered by AI and technology to do their best work.” - Patrick Conway,...
03/27/2026

“I think it’s going to be humans at the center, empowered by AI and technology to do their best work.” - Patrick Conway, MD, MSc, CEO of Optum

A conversation with Jamie Metzl, JD, PhD, technology and healthcare futurist and Founder & Chair, One Shared World to discuss how AI is moving from theory into everyday healthcare decisions.

02/28/2026

Day 3 marked a powerful close to

At the GuideWell Innovation Center, conversations spanned system-wide healthcare alignment, modernized health technology, regenerative medicine, and precision diagnostics, balanced by moments of reflection on vulnerability and healing.

A fitting finale to three days defined by breakthrough thinking and deeply human perspective.

We are already looking forward to next year!

The Mavericks: Transforming the Patient ExperienceHealthcare navigation shouldn’t feel harder than managing your finance...
02/27/2026

The Mavericks: Transforming the Patient Experience

Healthcare navigation shouldn’t feel harder than managing your finances or booking travel online, yet for many patients, it still does.

In this dynamic session, Marc Harrison, MD, Chair of the TowerBrook Healthcare Institute joined Glen Tullman, CEO of Transcarent, for a forward-looking conversation moderated by Renee Wegrzyn, PhD, Inaugural ARPA-H Director and Co-Founder of Transfyr.

Together, they explored how Transcarent is redefining the patient experience through AI-driven digital solutions that simplify access to comprehensive, personalized care.

Accelerating the “Magic Cycle” of Health Discovery From Science to RealityWe are living in a golden age of discovery whe...
02/27/2026

Accelerating the “Magic Cycle” of Health Discovery From Science to Reality

We are living in a golden age of discovery where the distance between breakthrough research and real-world impact is shrinking faster than ever before.

In this forward-looking session, Yossi Matias, PhD, VP at Google and Head of Google Research, explored how Google thinks about this acceleration through what he calls the “Magic Cycle.”

From AI-driven insights to scalable global solutions, the conversation highlighted how integrating research, technology, and real-world application can dramatically compress timelines, turning years of progress into months.

“Now, just to give a sense of the kind of geospatial models that we have, we've been working with that for many years. For example, we have a model for floods which enable us to provide flood prediction up to in 150 countries, covering 2 billion people up to seven days in advance.”

Kill the Clipboard: The Top 5 Things to Modernize Tech and Change LivesIn this energizing session, Amy Gleason shared he...
02/27/2026

Kill the Clipboard: The Top 5 Things to Modernize Tech and Change Lives

In this energizing session, Amy Gleason shared her journey from ER nurse to federal health tech leader and outlined the top five areas where modernizing technology can meaningfully improve lives.

Drawing on her experience as Acting Administrator at the U.S. Department of Government Efficiency (DOGE) and Strategic Advisor at CMS, Amy challenged us to rethink outdated systems, eliminate friction, and design solutions that truly serve patients and providers.

Moderated by Alexandra Drane, Co-Founder & CEO of ARCHANGELS, the conversation grounded big policy and tech conversations in real human impact.

“I hope we’re remembered for modernizing systems and making it easier to access critical government services, especially in stressful times of your life like getting Social Security or Medicare.” - Amy Gleason

02/27/2026

Day 2 at

Conversations focused on the future of higher education, the longevity economy, healthcare innovation, and the role culture plays in public health.

A standout moment: David Fajgenbaum MD, MBA, MSc, receiving the Adversity to Impact Award for turning personal adversity into life saving innovation.

Day 3 is happening now.

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9801 Lake Nona Boulevard
Orlando, FL
32827

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+14078886500

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