03/20/2026
Niacin...amazing! Used it for decades! See my comment below for a great brand and potential for free shipping too.
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Niacin is one of the B class vitamins, also known as vitamin B3. It is typically found in two available forms: nicotinic acid (pyridine-3-carboxylic acid) and nicotinamide (niacinamide or pyridine-3-carboxamide). There are other forms, but for the purpose of our discussion, these are the two main ones to focus on.
Both of these forms of B3 are taken in by cells of the body and converted into the metabolically active form, coenzyme nicotinamide adenine dinucleotide (NAD). There are more than 400 enzymes that require NAD to catalyze reactions in the body, which is more than for any other vitamin-derived coenzyme. As it sounds, it’s pretty important for our health.
When it comes to cancer, we have discovered that niacin helps maintain the integrity of genetic material, control of gene expression, cellular communication, and plays a major role in maintaining cellular antioxidant function; all of which are critical components of preventing damaged cells that can become cancerous.
Not only has niacin been demonstrated to help prevent cancer, there is also research showing that higher levels of niacin intake are linked to increased survival rates among cancer patients.
It seems that overall, studies indicate that NAD helps prevent mutated cancer cells from surviving; or in other words, a niacin deficiency promotes the survival of mutated cancer cells. Therefore, it makes sense to ensure adequate niacin intake, especially if you have cancer.
Niacin has been shown to play a role (along with riboflavin and CoQ10) in restoring oxidative phosphorylation in animal models of breast cancer, a biochemical process often impeded in cancer cells.
Another study in breast cancer cells showed that the enhancement of mitochondrial complex I activity inhibits tumor growth and metastasis through regulation of the tumor cell NAD redox balance, mTORC1 activity, and autophagy. Conversely, reduction of NAD levels rendered tumor cells more aggressive and increased metastasis in a mouse model.
Niacin seems to act directly on monocytes by inhibiting toll-like receptor (TLR)-4 (leading to decreased NF-κB) and TLR-2 induced expression and secretion of pro-inflammatory cytokines TNF-α, interleukin-6, and MCP-1 in human monocytes. This leads to an anti-inflammatory effect that is believed to help with cancer survival.
The major cause of death in many cancers is when a tumor becomes metastatic, meaning it spreads to other parts of the body. Niacin has been shown to help prevent metastasis in liver cancer, breast cancer, and colon cancer; especially when combined with other therapies.
There is research showing that when niacin is added to other treatments there are better outcomes. The researchers observed reduced tumor volume and prolonged survival when giving the mice niacin. What’s even more promising, is that when they combined niacin with temozolomide, it produced even better results.
The combo prolonged survival in a mouse model by at least fivefold.
Some of the newest research on cancer is showing that a major obstacle to treating tumors is that they distort the blood vessels that feed them and make it difficult to deliver treatments into the tumor cells.
It is very likely that one of the reasons niacin helps treatment outcomes is that it expands the blood vessels and gets the treatments into the tumor, where they have their greatest impact.
Read the full article here:
https://anticancer360.com/how-niacin-helps-win-the-fight-against-advanced-stage-cancers/
For a broader overview of our overall approach, please watch our webinar here:
👉 https://anticancer360.com/webinar/
At the end of the webinar, you can book a free assessment call with someone from our team to discuss your case in more detail and ask any questions you may have.
