03/19/2026
The AHA dyslipidemia guidelines have changed again, and hereβs what I'm genuinely glad to see:
Apo-B, a measure of the actual number of plaque-forming particles in the blood, is finally getting some press as a more accurate indicator of cardiac risk than LDL alone. I recommend checking your Apo-B yearly. Even if insurance doesn't cover it, this is an affordable test worth self-paying for. It is also recommended to have Lp(a) checked once in your adult life β this is a genetically determined, stable marker of cardiovascular risk. Elevated Lp(a) signals higher inherited risk for cardiovascular disease, independent of cholesterol levels. Still, high cholesterol and heart disease are not genetic inevitabilities, and most cardiovascular disease is preventable!
Lipid targets are back, and frankly always should have been. If your LDL cholesterol is over 100, you should be actively modifying your lifestyle to lower it. High LDL should not be normalized. Yes, itβs extremely common - so is heart disease. LDL target for high-risk individuals is less than 70, and for individuals with established cardiovascular disease less than 55. Itβs remarkable just how responsive LDL is to lifestyle changes. Less saturated fat. More fiber. Regular exercise.
Children should be universally screened for dyslipidemia between the ages of 9-11 and high-risk children may even need earlier screening. Pediatric metabolic dysfunction is increasingly common.
Where I disagree:
Starting routine screening at age 30 is too late, and the recommendation for every 4-6 years is just inadequate. It is very well established that lifetime exposure to LDL cholesterol drives cardiac risk. I see individuals with high cholesterol of all ages, every single day; in fact, it is far less common to see someone with "normal" cholesterol. Get screened early. Get screened yearly. Know your risk and modify what you can - because you can modify a lot π