02/17/2026
Everyone
𧬠Alpha-Gal + MCAS⦠are they connected?
Many patients with Alpha-Gal also have symptoms of mast cell over-activation.
When mast cells are hyper-reactive, they can release excess histamine π₯ β making reactions:
β³ Delayed
π₯© Fat-sensitive
β οΈ Unpredictable
π‘ More intense
You might see:
π€’ GI distress
π§ Brain fog
π Palpitations
π΅ Dizziness
π« Throat tightness
Itβs not βjust allergies.β
Itβs an immune over-response pattern.
Thatβs why we focus on:
β Stabilizing Response
β Identifying triggers
β Conservative progression after SAAT
β Careful monitoring
If Alpha-Gal still feels unpredictable, mast cell activation may be part of the picture.
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