Eleonora Teplinsky, MD

03/07/2026

Love that this year is on International Women’s Day and this message is empowered women empower women is one of my favorites - and why I am so passionate about education and advocacy.

A marathon is challenging on a good day but tomorrow is going to be especially tough with temperatures predicted to be in the mid 80s at the finish. A big change from the 14 degree ❄️ training runs this winter!
Hoping to go out there and have fun and enjoy the LA sights!

03/06/2026

New Substack on alternative treatments and misinformation in cancer and a new study making headlines about complementary and alternative therapies and breast cancer outcomes. The 📰headlines are a bit sensational and click-bait so I break down what the actual study tells us.

Read Substack here: https://open.substack.com/pub/drteplinsky/p/breast-cancer-complementary-and-alternative?r=645vr&utm_medium=ios

Study reference: Ayoade OF, Caturegli G, Canavan ME, Resio BJ, Berger ER, Boffa DJ. Use of Complementary and Alternative Medicine in the Management of Breast Cancer. JAMA Netw Open. 2026;9(3):e260337. doi:10.1001/jamanetworkopen.2026.0337.

03/04/2026

March 3rd is Triple Negative Breast Cancer Day and I can’t think of a better day to tell you about a new study just published in Nature of a first in human phase 1 trial of a personalized mRNA neoantigen TNBC vaccine.

The patient population was 14 individuals with surgically removed, early-stage triple-negative breast cancer. For each participant, researchers created a personalized mRNA vaccine encoding up to 20 neoantigens. Neoantigens are proteins that forms on cancer cells when certain mutations occur in tumor DNA. The goal was to train the immune system to recognize these neoantigens as foreign and attack tumor cells that carry these neoantigens. The goal is to reduce risk of recurrence and/or eliminate microscopic disease.

What they found was that the vaccine was well tolerated and either expanded pre-existing or induced immune-cell responses against at least one vaccinated neoantigen in all 14 evaluable individuals. Eleven patients remained relapse-free for up to six years post-vaccination (!!).

This is very early but promising and encouraging data! Multiple TNBC vaccines are in development (can search on clinicaltrials.gov) and I’m hopeful for the future!

Let me know all your questions!

03/01/2026

New Interlude Podcast episode with ! Amy is a breast cancer survivor and spiritual coach and mentor who helps women rebuild after life-shaking experiences. After surviving cancer, she began a journey of emotional healing and spiritual reconnection that shaped how she now lives and leads. Through coaching, programs, and retreats, Amy guides women to reconnect with themselves and step into their next chapter with more confidence, purpose, joy, and passion. Amy is also the bestselling author of “Baring it All: Reflections of My Breast Cancer F*ckery”, and a dynamic speaker who lights up a room and emanates vibrant energy.

On today’s episode, we talk about taking care of your mental health, starting to feel at home in your body again, trusting yourself and finding community and connection. Amy is hosting the upcoming RISING Retreat, an intimate retreat for breast cancer survivors and women living with metastatic disease to rest, reconnect with their bodies, and unapologetically claim who they are. Amy also shared a beautiful meditation she recorded to help women regain trust in themselves and in their bodies after breast cancer.

You can find this episode of the Interlude Podcast anywhere you listen to podcasts or on my website, www.drteplinsky.com. Comment PODCAST and I’ll send you the link to the episode and to the meditation!

03/01/2026

190. Amy Banocy (Breast Cancer Survivor and Spiritual Coach and Mentor)

On today's episode, I am speaking with Amy Banocy. Amy is a breast cancer survivor and spiritual coach and mentor who helps women rebuild after life-shaking experiences. After surviving cancer, she began a journey of emotional healing and spiritual reconnection that shaped how she now lives and leads. Through coaching, programs, and retreats, Amy guides women to reconnect with themselves and step into their next chapter with more confidence, purpose, joy, and passion....

On today’s episode, I am speaking with Amy Banocy. Amy is a breast cancer survivor and spiritual coach and mentor who helps women rebuild after life-shaking experiences. After surviving cance…

03/01/2026

I went for my mammogram a few weeks ago. I have dense breasts so I also had an ultrasound done! 🙌 all was negative. Mammograms save lives and help us diagnose breast cancer at its earliest point!!

3 key facts to know about breast cancer screening:

1️⃣ Know your breast cancer risk. Screening for average risk individuals starts at 40 but earlier for higher risk individuals. There are many models available to calculate your breast cancer risk including the Tyrer Cuzick model.

2️⃣ If you have dense breasts, consider adding in supplemental screening w MRI or breast ultrasound.

3️⃣ If you are at higher than average risk, you might benefit from supplemental imaging with ultrasound or MRI.

Are you up to date with breast cancer screening?! Let me know your questions!

02/28/2026

Answering your questions on ovarian suppression in breast cancer:

1) Do you still get a period?
2) Does switching from Lupron to Zoladex or vice versa help with side effects?
3) Oophorectomy (removal of ovaries) vs ovarian suppression w Lupron or Zoladex?

Hope this helps and let me know other questions you have!

02/28/2026

Let’s talk about circulating tumor DNA. If there are cancer cells in the body, as they die, a small amount of cancer cell DNA is released into blood circulation. We can sequence the primary tumor to identify the mutations present in the cancer, and then test for those mutations in the blood. Detection of circulating tumor DNA (ctDNA) in blood, after treatment for primary breast cancer, is associated with a higher risk of future recurrence. Signatera is one test available to look for ctDNA but there are many others (through companies like Caris and Guardant as well). ***we can’t always detect ctDNA especially in early stage cancer and there are limitations to the technology as well.

There is some nuance with this test and we often don’t know what to do if the results come back positive but staging scans are negative. Fortunately, there are many ongoing exciting clinical trials with ctDNA in breast cancer looking at interventions so hopefully we will have more answers soon! Currently on clinical trials.gov, there are about 100 breast cancer ctDNA trials! I want to highlight three that I think are important (but there are others!):

1. Decreasing Treatment for Metastatic HER2-Positive Breast Cancer With Undectable Cancer Levels in Blood Tests. (HEROES)

2. DNA-guided Second Line Adjuvant Therapy for High Residual Risk, Estrogen Receptor Positive, HER-2 Negative Breast Cancer (DARE) (DARE)

3. Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)

Let me know your questions or thoughts on !

02/26/2026

If you’re on ovarian function suppression with Lupron or Zoladex for breast cancer, here are important facts to know!

02/25/2026

We are increasingly testing for lipoprotein(a) as part of your
cardiovascular and cholesterol work-up. Lipoprotein(a) is a type of LDL (low-density lipoprotein) and is a particle in the blood that carries cholesterol. Lipoprotein(a) is an independent risk factor for
cardiovascular disease and is largely genetically determined.

As an oncologist, I discuss this because many cancer treatments can increase cardiovascular risk and knowing your baseline cardiovascular
risk is important. Some cancer treatments may also impact
lipoprotein(a) levels although more research is needed.

Because lipoprotein(a) is inherited and does not significantly change with diet or exercise, it only needs to be checked once in most people. The guidelines vary slightly regarding who should be tested,
but it can be helpful for the right person. I go through more details and a recent study in the video but I urge you to talk to your team about lipoprotein(a) testing and whether this is something that might be right for you to do.

There are currently no FDA-approved medications specifically for lowering high lipoprotein(a) but several,
highly effective, targeted therapies are in late-stage clinical trials. If you do have a high lipoprotein(a), it is a good idea to see a cardiologist to discuss your cardiovascular risk and appropriate ways to lower it through lifestyle and medications as appropriate.

Have you had lipoprotein(a) checked? Let me know questions and comments!

02/24/2026

📣 So excited and honored to be moderating this panel with this incredible group of patient advocates: , and . We will be talking about all things survivorship after a breast cancer diagnosis - topics like sexual health, mental health, fertility, finding community, body image, advocating for yourself and much more. It’s going to be such a powerful conversation and I urge you to join us!!

The whole event is going to be wonderful with fantastic panels and talks throughout the day. This will be my third year participating and it keeps getting better and better.

Go to www.letstalkwellwomen.org to register and use code Eteplinsky50 for 50% off your ticket! I hope to see you there!!

02/22/2026

New Substack is here all on Breast Cancer Index, a tool that we can use to guide duration of endocrine therapy beyond 5 years in HR+ breast cancer. In this Substack, I go into:
🔸 What BCI is?
🔸 How and when it is tested
🔸 What BCI tells us
🔸 What ASCO and NCCN guidelines recommend
🔸 Use of BCI in HER2+ and premenopausal BC
…and more!

You can find the Substack at https://open.substack.com/pub/drteplinsky/p/breast-cancer-index-bci-should-you?r=645vr&utm_medium=ios.