11/11/2025
GLP-1s + Hormone Therapy: A New Possibility for Midlife Women? New research suggests hormone therapy may enhance the effects of GLP-1 medications like tirzepatide in postmenopausal women.
In the study, every group lost body fat—but women on HRT lost the most. Nearly 20%. That’s a meaningful difference—and it raises smart, personal questions about what works best in midlife.
Important: HRT isn’t a weight loss tool. But your hormone status could influence how well these medications work. If you're navigating menopause and considering GLP-1s, this is a conversation worth having with your care provider.