03/19/2026
NEW IN JVIR: Percutaneous Radiofrequency Ablation of Perivascular versus Nonperivascular Hepatocellular Carcinomas ≤ 3 cm: Local Tumor Progression and Survival in an Inverse Probability of Treatment Weighting Analysis
🔍 Clinical Question:
To determine whether perivascular hepatocellular carcinoma (HCC) is associated with higher local tumor progression (LTP) and lower overall survival (OS) after percutaneous radiofrequency ablation (RFA) than nonperivascular HCC.
💡 Key Insight:
Perivascular hepatocellular carcinomas ≤ 3 cm showed higher local tumor progression after radiofrequency ablation. Perivascular tumors had lower overall survival compared with nonperivascular tumors. Rates of Society of Interventional Radiology (SIR) Grade C-E adverse events were comparable between the two groups.
👉 Why it matters:
These findings confirm that perivascular tumor location is associated with higher recurrence and lower survival after RFA for small HCCs, even after rigorous statistical adjustment. Identifying perivascular location should prompt careful treatment planning and consideration of adjunctive or alternative strategies.
➡️ Full Article: https://brnw.ch/21x0SDa