04/01/2026
Researchers are launching a major study to better understand something many women have experienced but few have talked about:
The link between perimenopause and serious mental health changes.
We've known that depression and mood shifts can increase during midlife. What's less discussed is that risk for more severe psychiatric symptoms can also rise during this hormonal transition.
This new study will track daily hormone fluctuations in women ages 40-60 to better understand how shifting estrogen and progesterone may impact brain health.
Why this matters: Perimenopause isn't "just hormones." It's a neurological transition.
And for many women, mental health changes during this time are real, biological, and deserving of proper attention.
https://msutoday.msu.edu/news/2025/10/researchers-lead-$37m-study-to-shed-light-on-perimenopause-and-psychosis