03/10/2026
Fuchs’ Dystrophy occurs when the cells in the cornea’s inner layer gradually deteriorate without any apparent reason. As more endothelial cells are lost over the years, the endothelium becomes less efficient at pumping water out of the stroma (the middle layers of the cornea). This causes the cornea to swell and distort vision. Eventually, the epithelium also takes on water, resulting in pain and severe visual impairment. Epithelial swelling will also produce tiny blisters on the corneal surface. When these blisters burst, they are extremely painful. (re: )