12/19/2025
If true, high sugar consumption can also exacerbate periodontal disease.
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Several large-scale studies have found strong links between high sugar consumption and increased risk of heart disease, particularly through its effects on insulin resistance, inflammation, and metabolic stress.
Excess added sugar can raise triglyceride levels, promote fatty liver disease, and contribute to chronic inflammation — all major risk factors for cardiovascular problems, even in people with normal cholesterol levels.
Researchers emphasize that this does not mean cholesterol plays no role, but rather that refined sugars and ultra-processed carbohydrates may be a more significant driver of modern heart disease than previously believed.
Historical analysis has also shown that dietary guidelines for decades focused heavily on fat and cholesterol, while the cardiovascular risks of sugar were often downplayed or underreported.
Health experts now recommend prioritizing whole foods, reducing added sugars, and focusing on overall metabolic health rather than targeting cholesterol alone.
