04/08/2023
Interesting article on MI
"Our case is interesting because it demonstrates a combined mechanism of MI hand dermatitis: (i) although not traceable, a probable direct contact with MI present in (a) product(s) of the patient's working environment (canalisations and plumbing at private citizens home), (ii) confirmed contact with nitrile protective gloves, likely contaminated by MI from the work environment, and (iii) additional exposure to (low/residual levels of) MI in new protective gloves. Although in the present case it concerned nitrile gloves, it has been previously described that some rubber gloves (i.e., natural latex rubber) might not always prevent MI pe*******on 4 ; however, this particular feature (pe*******on of MI through nitrile rubber gloves) was not investigated in our case. Finally, we cannot exclude that MI‐dependent contact dermatitis was further maintained due to frequent exposure to rinse‐off cosmetics or detergents. 5 In our patient, regular changes of new gloves every 3 days lead to a relative improvement, but no clearance, of his hand dermatitis. In practice, clinicians must be aware that, occasionally, protective nitrile gloves might contain isothiazolinones, inherently or by contamination, which might potentially aggravate existing hand dermatitis." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546190/
