WPI WPI is dedicated to solving ME/CFS and other complex infection-associated chronic diseases.

A medical research center dedicated to the discovery of the mechanisms of disease, creating diagnostics, and promoting effective treatments for those who suffer from ME/CFS and other chronic post-infectious diseases.

Amplify Wednesday!This article explores a leading ME/CFS hypothesis through both rigorous science and lived experience. ...
01/21/2026

Amplify Wednesday!

This article explores a leading ME/CFS hypothesis through both rigorous science and lived experience. Published on Health Rising by Cort Johnson, who lives with ME/CFS himself, the depth of research and insight really shows. If you’ve ever felt like patients often understand this illness more deeply than the system does, this is well worth a read!

Klaus Wirth shows how ME/CFS and long COVID may be acquired muscle diseases caused by poor blood flows and mitochondrial dysfunction

ME/CFS is a real, complex, and disabling illness — even when it’s invisible.One of the most powerful ways families can h...
01/15/2026

ME/CFS is a real, complex, and disabling illness — even when it’s invisible.
One of the most powerful ways families can help is by believing what their loved one says about their body.
Belief reduces isolation. Belief builds safety. Belief is a form of care.


If winter feels harder, you’re not imagining it.An NIH study found that many people with ME/CFS experience a clear worse...
01/13/2026

If winter feels harder, you’re not imagining it.

An NIH study found that many people with ME/CFS experience a clear worsening of symptoms in winter, including fatigue, pain, sleep disruption, anxiety, and low mood.

For some, symptoms even mirror Seasonal Affective Disorder patterns. This research helps validate what so many patients report every year and opens the door to supportive options like light therapy for certain subgroups

Check out the article below!

This study aimed to determine symptom patterns in patients with chronic fatigue syndrome (CFS), in summer and winter. Comparison data for patients with seasonal affective disorder (SAD) were used to evaluate seasonal variation in mood and behavior, atypical neurovegetative symptoms characteristic of...

Did you know fiber impacts more than digestion?It can influence gut health, inflammation, and metabolic stability, areas...
01/07/2026

Did you know fiber impacts more than digestion?
It can influence gut health, inflammation, and metabolic stability, areas often affected in ME/CFS.
Knowledge is one tool in self-advocacy.


Advocacy doesn’t have to be loud to be powerful.In 2026, may you choose what supports your body, your energy, and your w...
01/01/2026

Advocacy doesn’t have to be loud to be powerful.
In 2026, may you choose what supports your body, your energy, and your wellbeing, one boundary, one question, one moment at a time.

Happy holidays to our community.

What happens when healthy human muscle is exposed to ME/CFS blood?This new study used a “muscle on a chip” model and fou...
12/29/2025

What happens when healthy human muscle is exposed to ME/CFS blood?

This new study used a “muscle on a chip” model and found that ME/CFS and long COVID serum directly weakened muscle tissue—especially in ME/CFS.

The findings add to growing evidence that something in the blood is driving muscle dysfunction, not deconditioning. A powerful step toward understanding post-exertional malaise and energy failure.

Read the full breakdown from Health Rising below.⬇️

Geoff’s Narration The GIST Muscles on a Chip Whoa, another muscle study. We recently reported on a proteomic study suggesting that muscle repair problems contribute to post-exertional malaise in ME/CFS. Now, we have a direct muscle test – and even better – we get to see whether something in th...

From our community to yours, we’re sending warm holiday wishes and gratitude for the connection we share.              ...
12/24/2025

From our community to yours, we’re sending warm holiday wishes and gratitude for the connection we share.

12/22/2025

It’s so good to hear your voice, Whitney!
Thank you for sharing this milestone with the community and for continuing to show what honesty, patience, and courage can look like with severe ME/CFS.
Your voice, in every sense, continues to inspire so many of us.

Help us bring hope to millions living with ME/CFS.Your donation to DiscoverME fuels vital research dedicated to finding...
12/19/2025

Help us bring hope to millions living with ME/CFS. Your donation to DiscoverME fuels vital research dedicated to finding answers, treatments, and ultimately—a cure.

12/18/2025

The holidays can be beautiful—and overwhelming.
If your energy is limited, rest is care.
If your presence is quiet, it still counts.
We see you.


Knowledge is empowerment — especially when living with ME/CFS.Your support helps us educate patients, caregivers, and co...
12/12/2025

Knowledge is empowerment — especially when living with ME/CFS.

Your support helps us educate patients, caregivers, and communities across the nation, spreading understanding and compassion for those affected.

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