ReGenesis HRT

01/11/2026

Worried about hair loss with Testosterone Therapy?

Testosterone itself is not directly responsible for hair loss; rather, it’s its derivative, dihydrotestosterone (DHT), that plays a crucial role in androgen-mediated hair loss, particularly in individuals genetically predisposed to androgenetic alopecia or male pattern baldness.

Testosterone delivered through transdermal cream (especially on skin with high 5‑α‑reductase such as scrotal skin) tends to generate about 2–3 times more DHT elevation than typical injectable preparations like testosterone cypionate, for the same degree of testosterone replacement.

What is known quantitatively

1. Transdermal (cream/gel) vs intramuscular injections overall

A meta‑analysis of testosterone replacement trials found:
Transdermal TRT (gels/patches) increased serum DHT about 5.46‑fold over baseline.

Intramuscular TRT (which includes esters like testosterone cypionate/enanthate) increased DHT about 2.20‑fold over baseline.

Scrotal skin has particularly high 5‑α‑reductase activity, so scrotal cream is generally considered to produce even higher DHT/T ratios than standard non‑scrotal gels

01/09/2026

01/09/2026

Providers and insurance want 2 separate 7:00am tests, which is when testosterone levels are highest. Men don’t live their lives at 7:00am. I’ve seen levels drop dramatically by early afternoon. Too much emphasis on total T levels and not enough understanding of s*x hormone binding globulin, free and bioavailable levels. Not to mention, SYMPTOMS. Estradiol levels are important as well. Finally, subclinical or compensated hypogonadism presents with symptoms of low testosterone, despite normal serum testosterone, frequently due to elevated LH or high S*x Hormone-Binding Globulin (SHBG.) However, physicians only tend to look at total T and ignore symptoms. As a result, we have a generation of men who go out and self-treat with black market testosterone, inappropriately. So we have a big problem on the horizon with all these men who were turned away to treat themselves.

Low testosterone is about health, not just strength. It can be a sign of issues like diabetes, metabolic problems, or depression. That makes a testosterone test more than routine bloodwork. It’s a simple window into a man’s overall health.

12/26/2025

The newest addition to my family…Boss!

12/26/2025

The newest addition to my family…Boss! My man!

09/20/2025

Telemedicine laws for prescribing testosterone:

It’s almost October. If you get your testosterone via telemedicine-only on-line providers, you only may have 2 months to find a new provider that you will have to see face to face. Your current telehealth provider will only be allowed to give you a 30 day bridge prescription to hold you over until you either go see their doctor face to face OR find a new, local provider that sees you face to face. Don’t wait until the last minute! ReGenesis HRT never stopped requiring a face to face visit up front for testosterone therapy.