03/12/2026
Fact: Giving blood fits into your day. 🩸
Both Mayo Clinic Blood Donor Centers in Rochester, MN are open 6:00 a.m. to 4:30 p.m., Monday through Friday. Holiday hours may vary.
To make donating even more convenient, the Hilton Donor Center stays open until 7:00 p.m. every second Thursday of the month—and today is one of those late‑night opportunities.
Downtown Rochester
Mayo Clinic
Hilton Building
First Floor
210 2nd St SW, Rochester, MN 55905
Northwest Rochester
Mayo Clinic Medical Complex Northwest
Building A, Door A1
First Floor, Room 110
4115 W. Frontage Road, Rochester, MN 55901
Ready to donate? Schedule your appointment at the link in our bio or give us a call at 507-284-4475.