Cole's Pharmacy

Cole's Pharmacy Updated with the latest computer technology, we can process most major insurance companies scripts. Cole's has an excellent selection of candies.

Friendly atmosphere with a nostalgic setting - discount store, pharmaceutical needs, medical supplier, vintage drug store circa 1950, cold and flu medications, diabetic needs. We cater to senior citizens and tally prescriptions for your household income needs. Coles carries a large selection of collectibles: dolls, lighthouses, sporting memorabilia, postcards, jewelry and many gift items at great prices.

Good morning and Happy Holidays to everyone! Posted below is a list of Cole's Pharmacy's upcoming store holiday hours. S...
12/19/2025

Good morning and Happy Holidays to everyone! Posted below is a list of Cole's Pharmacy's upcoming store holiday hours. Stop by the drugstore tomorrow between 11AM-1PM to meet Santa Claus and enjoy a cup of hot chocolate with mini marshmallows for just $2!

12/12/2025

Stop by today and enjoy our Hot Dog meal deal....the meal deal consists of two hot dogs, small bag of chips and a large fountain soda for only $8.00. Our grill is open from 10am-4pm Monday thru Friday and 10am-2pm on Saturdays.......
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Let's talk about Saturday, December 13th, 2025. Roxboro and Person County has a favorite visitor stopping by for his annual trek along Main Street tomorrow......it's Santa Claus in his sleigh riding in the annual Roxboro Christmas Parade sponsored by The Roxboro Jaycees. The parade will kick off at 2pm tomorrow so there will be plenty of time to stop in for some hot dogs, orange aides, lemon aides, HOT CHOCOLATE, sandwiches and other goodies from the grill. The weather looks really good for the parade tomorrow so stop in for the best deal in the Rock and we look forward to seeing all of you on Main Street in Uptown City of Roxboro!!
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12/10/2025

Our grill is open today after a 3 day closure due to the snow/ice event that Person County endured recently....so, let's stop in and grab the $8.00 hot dog meal deal which includes two hot dogs, small bag of chips and a large fountain soda. Our grill is open from 10am-4pm Monday thru Friday and 10am-2pm on Saturdays. Stop by we are dealing!!

Our pharmacy is open as well so stop by to pick up your prescriptions!! We will be here till 5pm!!

Cole's Pharmacy will be closed today, Monday, December 8th, at 12 Noon. ❄️❄️❄️❄️❄️❄️❄️❄️❄️❄️❄️❄️❄️❄️❄️ We anticipate reo...
12/08/2025

Cole's Pharmacy will be closed today, Monday, December 8th, at 12 Noon. ❄️❄️❄️❄️❄️❄️❄️❄️❄️❄️❄️❄️❄️❄️❄️

We anticipate reopening on Tuesday, December 9th, at 12noon, subject to further weather updates that may impact road conditions and staff safety. The Grill will be closed on Tuesday, December 9th.
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We appreciate your business and encourage you to stay safe and warm.

12/08/2025

Cole's Pharmacy will close today--12-8-25--Monday at 12 noon due to the incoming weather. We are open NOW so please call or come by to pick up your medications.

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Cole's Pharmacy will also be closed from 9am-12noon of Tuesday 12-9-25 due to icy road conditions that are forecast throughout the day and night. Currently, Cole's Pharmacy plans on opening on Tuesday at 12 noon thru 5pm but this may change as well due to the weather. We will update accordingly due to the weather as we move forward.
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The grill is CLOSED today, Monday, 12-8-25 and Tuesday, 12-9-25.

12/04/2025

Cole's Pharmacy will be open tonight for the "Jingle on Main" Celebration. We will be serving up our world famous hot dog meal deal which includes 2 hot dogs, small bag of chips and a large fountain soda for only $8.00. We will also have orange aides, lemon aides, sandwiches, BBQ, Chicken Salad to choose from to quench your appetite. Did we mention we are serving up some good ole HOT CHOCOLATE to chase the chill away?? Yes......stop in to warm up and hang out a while during the celebration of Jingle on Main!! We will be open until 8pm tonight.

We need to update our post from earlier this week regarding singing along to Karaoke tunes.....unfortunately, our karaoke machine is unavailable so there will be no karaoke tunes spinning but we will have Christmas music playing to enhance the ambience of Christmas at Cole's Pharmacy in Uptown Roxboro for the WIN!!

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IMPORTANT ANNOUNCEMENT: DUE TO THE WEATHER FORECAST FOR FRIDAY, DECEMBER 5TH, 2025. COLE'S PHARMACY WILL BE CLOSED ON FRIDAY, DECEMBER 5TH, 2025.
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COLE'S PHARMACY WILL BE OPEN ON SATURDAY, DECEMBER 6TH, 2025 FROM 10AM-2PM. OUR PHARMACY AND GRILL WILL BOTH BE OPEN TO SERVE ALL OF OUR PATRONS.
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12/02/2025

It's a really cold day out in the streets of Roxboro so we are serving up some of our good ole' Pinto Beans to blow the chill off the low temps and rain!! Our bean special consists of a hot bowl of Pinto beans, two very fresh slices of bread and a large fountain soda for only $5.95. Our grill is open from 10am-5pm Monday thru Friday and 10am-2pm on Saturdays. Stop in we are dealing!!

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OK! Cole's Pharmacy is hosting a Karaoke Christmas this year during the "Jingle on Main" Uptown Celebration this Thursday, December 4th from 5:30pm-8pm. We invite everyone to stop by and grab the microphone and belt out a few Christmas tunes for everyone to enjoy! It's a completely free event and who knows? Could you be the next "Roxboro's Got Talent" for the world to meet moving forward? We are looking forward to a good ole fashioned Christmas here in the heart of Roxboro and it will not be complete without you and your families gathered around singing, eating hot dogs and having a big ole' time!!!

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Keep an 👀 on our Holiday Hours! We thank you for your business and wish you a Safe & Happy Thanksgiving!🦃
11/24/2025

Keep an 👀 on our Holiday Hours!
We thank you for your business and wish you a Safe & Happy Thanksgiving!🦃

11/18/2025

Stop by for a bowl of hot Pinto beans, two fresh slices of bread and a large fountain soda for only $5.95. Our grill is open from 10am-4pm Monday thru Friday and 10am-2pm on Saturdays!! Stop by we are dealing!!

Oh my......we have gift giving on our minds today!! Stocking stuffers, sweat shirts, long sleeve t-shirts, knick-knacks,...
11/12/2025

Oh my......we have gift giving on our minds today!! Stocking stuffers, sweat shirts, long sleeve t-shirts, knick-knacks, flags, gloves, thick work socks for the WIN!! And.....did we mention toys? Yes!! Stop by Uptown Roxboro at Cole's Pharmacy for some gift ideas and grab our world famous Hot Dog lunch special.....the lunch special includes two hot dogs, small bag of chips and a large fountain soda for only $8.00.

Our grill is open from 10am-4pm Monday thru Friday and 10am-2pm on Saturdays! If you would like to call in an order for pick up please just reach out to 336-599-2171 and we will direct the call to the cooks at the grill and you can be on your way in a mere matter of minutes!!

11/11/2025

Cole's Pharmacy is serving up some good ole HOT Pinto Beans today for our lunch special. It's a cold fall day here in the Rock so let's warm up with a hot bowl of Pinto's, two fresh slices of bread and a large fountain soda for only $5.95. Our grill is open from 10am-4pm Monday thru Friday and 10am-2pm on Saturday's. Stop by we are dealing!!

HAPPY VETERANS DAY!!!!!!!!

11/08/2025

We had a great Veterans Day parade in Uptown City of Roxboro at 10am today!! It was awesome to see the smiling faces and admiration given to our well deserving Veterans of Person County!! Thanks to all of the Veterans far and wide for your incredible service to America!! We are truly blessed!!

Cole's Pharmacy is serving up our hot dog meal special today which includes two hot dogs, small bag of chips and a large fountain soda for only $8.00. Our grill is open from 10am-2pm today so stop on by and enjoy a delicious meal in Uptown Roxboro!!

Address

117 N Main Street
Roxboro, NC
27573

Opening Hours

Monday 9am - 5pm
Tuesday 9am - 5pm
Wednesday 9am - 5pm
Thursday 9am - 5pm
Friday 9am - 5pm
Saturday 10am - 2pm

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