11/21/2025
New cholesterol drugs are being promoted again, but here’s what most people still don’t realize:
LDL isn’t the real problem... oxidized LDL is:
Your body needs LDL for hormones, the brain, cell repair, and immune function. LDL only becomes dangerous after it’s damaged by oxidation.
What science shows:
1) American Heart Association & JACC: oxidized LDL (oxLDL) — not normal LDL — drives plaque formation.
2) ATVB & PNAS: oxLDL causes inflammation and artery damage.
3) Journal of Lipid Research: seed oils increase oxLDL.
4) Diabetes Care: high sugar and AGEs make LDL oxidize faster.
5) Clinical Chemistry: high triglyceride/HDL ratio = more oxidized, dangerous LDL particles.
What actually helps your arteries:
- Lower sugar & processed carbs (reduces AGEs).
- Cut seed oils; use stable fats like butter, tallow, avocado oil.
- Improve TG/HDL ratio.
- Lower overall oxidative stress (antioxidants, lifestyle).
- Do muscle resistance exercises to improve HDL numbers.
Bottom line, the science is clear:
LDL is not the enemy. Oxidation is. Fix the oxidative stress, and your arteries become far healthier than simply “drugging the LDL number down.”
And for the sake of avoiding drama:
Always consult your doctor before stopping any medication.
Do your research and have a proactive, informed conversation with a licensed professional.
A powerful new treatment has emerged in efforts to reduce high cholesterol levels and the associated risk of heart health problems.
