11/20/2025
Try this tomorrow morning: brush your teeth with your non dominant hand.
It will feel awkward and inefficient. That is exactly why it works.
Using your non dominant hand forces your brain to activate both hemispheres instead of relying on a single motor region. Brain imaging studies show that dominant hand movements mainly activate the contralateral motor cortex. Non dominant hand movements activate both the contralateral and ipsilateral sides, which means more of your motor network is working at once.
A study on non dominant hand precision training found that just 10 days of practice significantly improved coordination, and 77 percent of participants kept those improvements for six months. Training increased functional connectivity between sensorimotor areas, the posterior parietal cortex, and premotor regions. This is clear evidence of experience driven neuroplasticity. Research on learning to use chopsticks with the non dominant hand showed that six weeks of training decreased activity in the left dorsolateral prefrontal cortex, which indicates increased efficiency, while activity in bilateral premotor areas increased. This reflects deeper skill learning and expanded neural recruitment.
The reason this works so well is novelty.
New experiences trigger dopamine release, which boosts attention and helps the brain form stronger memories. Dopamine signals that a task is meaningful and should be learned. Studies show that novelty, focused attention, and challenge are powerful drivers of neuroplasticity throughout life. Even in middle aged animals, enriched environments with new tasks and exploration produced a fivefold increase in neural growth markers along with better learning and more exploratory behavior.
Your brain follows a simple principle: neurons that fire together wire together.
Automatic routines strengthen old pathways. New and unfamiliar tasks force the brain to build new ones. When you brush your teeth with your non dominant hand, your brain cannot rely on autopilot. It has to focus, coordinate, and adapt. That struggle is the signal for change.
Break the pattern. Try using your non dominant hand for daily tasks such as brushing your teeth, using your computer mouse, writing notes, stirring food, or eating with chopsticks. The discomfort you feel is your brain building new neural pathways. Challenge creates growth. Consistent novelty trains your brain the same way consistent weight lifting trains your body.
Build your brain daily.
Key Studies:
Philip and Frey 2016, Neuropsychologia. PMID: 27059395
Kim et al. 2019, Scientific Reports. PMID: 31882808
Dassonville et al. 1997, PNAS. PMID: 9391169
Kim et al. 2003, NeuroImage. PMID: 14568423
Kempermann et al. 2002, Journal of Neuroscience. PMID: 12077205
Mahncke et al. 2006, PNAS. PMID: 16916904
Merzenich et al. 1996, Science. PMID: 8553117