The Epi Center MedSpa

The Epi Center MedSpa The nation’s first MedSpa. Awarded Top MedSpa in the US. Visit our website for more details, to receive a $50 gift card and to schedule your free consultation.

We are a refuge for skin rejuvenation and renewal, providing a luxurious guest experience and the latest in skincare treatments. By combining medical grade products, our custom treatment programs achieve natural, lasting results in a soothing, eco-friendly environment. Our staff includes top nurse practitioners, physician assistants, registered nurses and licensed aestheticians with on-site supervision by medical doctors, working together so you achieve maximum results. We offer Botox, CoolSculpting, Microneedling, Laser Hair Removal ,PhotoFacial, PDO Nova Threads, Dermatology exams, Skin Tightening, Pixel Resurfacing, Restylane, Sculptra, Juvederm, Voluma, Botox and Dysport, Volume Lift, High-Speed Laser Hair Removal, Acne Treatments, Weight Loss Plans, Vitamin B Shots, Coolsculpting Suite, Cellulite Treatments, Microneedling with GH, Tattoo Removal, HydraFacial MD, Facials and more. Our specialized treatments correct sun damage, uneven pigmentation, brown and age spots, facial redness and rosacea, acne and acne scars, skin texture and tightening, facial lines and wrinkles, under eye rejuvenation, weight reduction and spider leg veins. We have been recognized at best Botox, best Laser Hair Removal, best CoolSculpting, best Microneedling and best PhotoFacial treatments in the Bay Area.

03/08/2026

Happy International Women’s Day! 🌸💪
Today, we celebrate the power, resilience, and leadership of women worldwide. Margaret Mitchell, our visionary CEO and Founder, embodies this spirit as the trailblazing force behind Epi Center MedSpa—a proudly women-owned and women-led institution that pioneered the medical spa concept in the nation.
As the first medical spa in the U.S., we’re proudly marking 27 years of innovation, stability, and excellence right in the heart of San Francisco. Our exceptional team weaves together a rich tapestry of diversity, representing 13 different countries and speaking 11 languages, enabling us to connect authentically and provide expert, inclusive care for every skin type and every story.
We are more than a medical spa—we’re a community dedicated to beauty, wellness, empowerment, and redefining aesthetic excellence through compassion and expertise.
In the spirit of , let’s continue lifting each other up: when we invest in women’s leadership, innovation, and care, we all thrive.
Here’s to Margaret and every woman driving change, healing, and beauty—today and always. Thank you for inspiring us!
Join us in celebrating this milestone of diversity, expertise, and women-powered excellence. ❤️✨
WomenInBusiness EpiCenterMedSpa SanFrancisco 27YearsOfExcellence

03/06/2026

✨ Check out this 2-week transformation! A few precise Botox injections by helped soften this gummy smile for a more balanced, confident look. 💉
Results like this are why we love what we do.

03/01/2026

Happy Birthday to our fabulous Botox Queen Inessa! 🎉💉✨Inessa, you are such an integral part of our Epi Center MedSpa team—for an incredible 23 years! Your expertise, warmth, and that signature glow you bring to every client (and to all of us) make every day brighter. Cheers to the best birthday ever, filled with all the love, light, laughter, and maybe a little extra pampering your heart can hold. We love you so much! 🩷 -Team Epi

02/22/2026

Happy Birthday, .rn! 🎉✨
From all of us at Team Epi: Cheers to our amazing aesthetic nurse whose artistry, compassion, precision, and radiant energy transform lives every single day. Your skill with a syringe (and a smile) brings out the best in everyone you touch, and your presence makes our team stronger, kinder, and more beautiful inside and out. May this birthday shower you with pure joy, endless glow, loving moments, sunny escapes, and all the adventures that make your heart light up. We’re beyond grateful you’re part of the Epi family. Here’s to celebrating YOU and the stunning year ahead! 🥂🌸 With so much love and the biggest team hugs,�Team Epi ❤️

02/07/2026

We love lip filler for Galentine’s Day

02/06/2026

When you’re stepping into the spotlight for Next Level CEO, you want to make sure you’re glowing from the inside out. ✨

​Margaret Mitchell , CEO/Founder of has put Jessica in the expert hands of her nurse, Karla , to map out a comprehensive plan for her skin. As she continues this journey, she’s getting real about the aging process and the importance of supporting collagen.

​Karla has designed a custom ‘road map’ for her which includes a chemical peel, Botox, microneedling, and Ultherapy. They weren’t just looking for a quick fix; they are focused on preserving youthful skin and ensuring she feels as powerful as she looks when the cameras start rolling! 📽️

​Jessica can’t wait to take you all along on this transformation.

​What’s your go-to skincare secret for staying confident? Let us know in the comments! 👇🏽





 Kysse 2025 Goodbye and Get Ready to Pucker Up for Valentines Day! Now through Valentines Day we will correct and plump ...
01/22/2026

Kysse 2025 Goodbye and Get Ready to Pucker Up for Valentines Day!

Now through Valentines Day we will correct and plump your lips with Kysse Lip Filler (Restylane) and correct smokers lines, frowns, dimpled chin and/or do a lip flip .

Filler treatment is $795 (1 syringe) and you receive up to 25 units of Dysport (equiv 10 units Botox) around the mouth area FREE!

415-362-4754 or schedule online https://epicentermedspa.zenoti.com/webstoreNew/services

When the Botox glow 🆙 and 👄 filler speaks for itself  by
01/09/2026

When the Botox glow 🆙 and 👄 filler speaks for itself by

01/09/2026

New Year, New You 2026 ✨ 💋

12/12/2025

REFRESH FOR THE HOLIDAYS✨💫
Mini glow up with this gorgeous girl by

11/27/2025

✨ BLACK FRIDAY SALE STARTS NOW at Epi Center MedSpa! ✨

The biggest savings of the year are HERE and they’re running ALL WEEK LONG through Cyber Monday! 💸💉💖

🔥 33% OFF site-wide
🎁 GIFT CARD BONUS (the more you buy, the more FREE money we add!):
💰 $100 → get $10 FREE
💰 $250 → get $25 FREE
💰 $500 → get $50 FREE
💰 $1,000 → get $150 FREE
💰 $2,000 → get $400 FREE!!

Plus FREE consultations in our brand-new Better Body Department 🤍

⏰ Starts TODAY 11/26 – Ends December 6th at midnight
Don’t sleep on these deals – they’re gone in a flash!

👉 Swipe up / Tap the link in bio / Click here to shop ALL the Black Friday specials:
https://conta.cc/48gUfpH

Treat yourself or someone you love to the gift of confidence and glow this holiday season ✨

Epi Center MedSpa's Black Friday Starts Now!!!
11/26/2025

Epi Center MedSpa's Black Friday Starts Now!!!

✨Our Black Friday Deals End Soon! The most anticipated shopping event of the year is finally here, and it's time to put yourself first! ✨DON'T MISS OUR✨ BLACK FRIDAY & CYBER MONDAY WEEK LONG SPECIALS!

Address

450 Sutter Street Rm 800
San Francisco, CA
94108

Opening Hours

Monday 10am - 6:30pm
Tuesday 10am - 6:30pm
Wednesday 10am - 7pm
Thursday 10am - 6:30pm
Friday 10am - 7pm
Saturday 10am - 6:30pm

Telephone

+14153624754

Alerts

Be the first to know and let us send you an email when The Epi Center MedSpa posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.

Contact The Practice

Send a message to The Epi Center MedSpa:

Share

Share on Facebook Share on Twitter Share on LinkedIn
Share on Pinterest Share on Reddit Share via Email
Share on WhatsApp Share on Instagram Share on Telegram

Category