Institute for Neurodegenerative Diseases

Institute for Neurodegenerative Diseases Discovering new therapies and diagnostics to treat brain diseases related to prions and protein abnormalities—CJD, Alzheimer's, Parkinson’s, TBI, dementia

Founded in 1999, the IND is committed to creating therapeutics that will halt diseases such as Alzheimer’s, Parkinson’s, Creutzfeldt-Jakob disease, and dementia resulting from traumatic brain injuries. Located at the University of California, San Francisco, the IND is at the forefront of discovering diagnostics and therapeutics that will provide relief to those suffering from neurodegenerative diseases that, in the words of British novelist and Alzheimer’s patient Terry Pratchett, can “strip away your living self a bit at a time.”

If we are hopeful about the long-term prospects of the battle against dementia, it is because our laboratories have an edge. For decades we have led the field in basic research on prions and other protein abnormalities and are now applying our time-tested approach to the wave of dementia that threatens our nation.

Companion volumes on the increasing role of   in human health and disease now available from Cold Spring Harbor Laborato...
11/15/2017

Companion volumes on the increasing role of in human health and disease now available from Cold Spring Harbor Laboratory Press http://bit.ly/2ijk4xm

The Prusiner Lab is recruiting postdocs. Maybe you have the background to apply?       http://bit.ly/2ons6aa
04/11/2017

The Prusiner Lab is recruiting postdocs. Maybe you have the background to apply? http://bit.ly/2ons6aa

Our postdoctoral training program prepares scholars to investigate the genetic, cellular, and biochemical mechanisms that underlie neurodegenerative diseases such as Alzheimer’s, Parkinson’s, tauopathies, and prion diseases. We train fellows to become independent investigators who are qualified to r...

02/10/2017

Huge congrats to IND Faculty Lisa Gunaydin and Martin Kampmann for being named Chan Zuckerberg Initiative Biohub Investigators! Biohub is a $600 million initiative to increase collaboration between UCSF, UC Berkeley, and Stanford University to advance research in the life and health sciences http://bit.ly/2d2yMG9

The IND's Kampmann Lab featured in No. 3: Identify potential Alzheimer’s treatments
01/03/2017

The IND's Kampmann Lab featured in No. 3: Identify potential Alzheimer’s treatments

The gene-editing tool’s potential to upend science is dizzying.

New research out of the IND suggests that chronic traumatic encephalopathy (CTE), an illness linked with repeated concus...
12/09/2016

New research out of the IND suggests that chronic traumatic encephalopathy (CTE), an illness linked with repeated concussions and brain trauma, is a prion disease http://bit.ly/2gmejQC

A shared biological mechanism may drive the progression of both Alzheimer’s disease and chronic traumatic encephalopathy, a neurodegenerative condition associated with repeated concussions and brain trauma.

The IND at   is searching for   fellows to work on groundbreaking research projects involving   diseases in humans. Do y...
05/16/2016

The IND at is searching for fellows to work on groundbreaking research projects involving diseases in humans. Do you have the background to apply? ind.ucsf.edu/careers/postdoctoral

03/11/2016

Recognizing scientific excellence and originality in PNAS, the National Academy of Sciences has awarded a 2015 Cozzarelli Prize to researchers in the IND for their discovery of a new strain shown to transmit neurodegeneration. Read the article posted below to learn more about their discovery.

In case you missed it, a big discovery in the IND was one of the most popular     stories of 2015. Read about the first ...
02/04/2016

In case you missed it, a big discovery in the IND was one of the most popular stories of 2015. Read about the first new human disease identified in 50 years: http://bit.ly/1P9yzwP

Multiple System Atrophy, a neurodegenerative disorder with similarities to Parkinson’s disease, is caused by a newly discovered type of prion, according to two new research papers led by scientists at UCSF.

07/25/2014

Share this story:SharePrintJuly 24, 2014Nobel Laureate Stanley Prusiner, MD, who discovered an unprecedented class of pathogens that he named prions, has been appointed to the board of directors for a newly created federal organization called the Foundation for Food and Agricultural Research (FFAR).…

07/12/2014

In the past few years, scientists have demonstrated that molecules involved in Alzheimer’s disease behave like the prion proteins that cause mad cow disease. That is, the Alzheimer’s molecules—amyloid-β peptide and tau protein—misfold in the brain and then coerce other molecules to do the same. The…

Public props to our research team.
07/12/2014

Public props to our research team.

More Evidence Ties Aβ Strains to Distinct PathologiesQuick LinksArticleComments (0)ReferencesFurther ReadingToolsAdd to my LibraryFollow CommentsEmailWith annotationsWithout annotationsShareHow would you like to share?FacebookTwitterLinkedInBack to the Top09 Jul 2014In two papers in the June 30 Proc…

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