NCIRE - Northern California Institute for Research and Education, Inc.

NCIRE - Northern California Institute for Research and Education, Inc. NCIRE – Northern California Institute for Research and Education, Inc. has one mission and one goal: Veterans' Health.

We are the leading nonprofit research institute in the United States devoted to advancing Veterans' health research. Through new technologies, novel scientific insights, and international clinical collaborations, we strive to set a new standard of health care for veterans and military personnel.

Geriatrics Team Publishes Updated Prognostic Model for Older Adults in Skilled Nursing FacilitiesDrs. W. John Boscardin,...
04/14/2026

Geriatrics Team Publishes Updated Prognostic Model for Older Adults in Skilled Nursing Facilities

Drs. W. John Boscardin, Alexander K. Smith, Sei Lee and their geriatrics research colleagues sought to improve upon a multi-outcome prognostic model for older adults admitted to skilled nursing facilities (SNF) for short-term rehab that had Medicare data.

In the updated model, the research team incorporated predictors from the Minimum Data Set (MDS), a mandated comprehensive assessment. This study sought to develop an updated model with MDS elements for use on day 7 of SNF admission when clinical trajectories are more established.

The study was published in the Journal of the American Medical Directors Association.

Read more here: https://www.jamda.com/article/S1525-8610(25)00620-6/fulltext?rss=yes

This April 14th, the U.S. Air Force Reserve officially celebrates its 78th birthday.Please join NCIRE in celebrating the...
04/14/2026

This April 14th, the U.S. Air Force Reserve officially celebrates its 78th birthday.
Please join NCIRE in celebrating the service members of the U.S. Air Force Reserve!

Learn more:
https://www.afrc.af.mil/

Divergent white matter metabolic signature patterns indicate impending cognitive decline in aging and dementiaWhite matt...
04/10/2026

Divergent white matter metabolic signature patterns indicate impending cognitive decline in aging and dementia

White matter (WM) is a key substrate for interregional neural communication and cognitive function, yet the role of WM glucose metabolism in cognitive aging has been understudied.

Drs. Michael Weiner, Duygu Tosun-Turgut, and Rachel Nosheny with the NCIRE-supported NIH Alzheimer's Disease Neuroimaging Initiative contributed to the study titled "Divergent white matter metabolic signature patterns indicate impending cognitive decline in aging and dementia”.

Read it here: https://www.nature.com/articles/s41467-026-70707-6

This National Public Health Week (NPHW), April 6th– 12th. An initiative of the American Public Health Association, NPHW ...
04/06/2026

This National Public Health Week (NPHW), April 6th– 12th. An initiative of the American Public Health Association, NPHW is a time to recognize all facets of Public Health and the holistic approach it takes for our communities to thrive. It is a goal that takes the combined efforts of individuals, families, communities, and the Public Health field to achieve.

NCIRE thanks our Public Health Workers and our Research Community for their tireless efforts to ensure improved public health.

Learn More: https://nphw.org/themes-and-facts

April is Parkinson’s Disease Awareness Month.Parkinson's disease (PD) is a progressive movement disorder of the nervous ...
04/03/2026

April is Parkinson’s Disease Awareness Month.

Parkinson's disease (PD) is a progressive movement disorder of the nervous system. It causes nerve cells (neurons) in parts of the brain to weaken, become damaged, and die, leading to symptoms that include problems with movement, tremors, stiffness, and impaired balance. As symptoms progress, people with Parkinson’s disease (PD) may have difficulty walking, talking, or completing other simple tasks.

In the U.S., nearly 1 million people are living with Parkinson’s disease, with about 90,000 being diagnosed each year.

Following Alzheimer’s disease, Parkinson's disease (PD) is the second-most common neurodegenerative disorder in the United States. Most people diagnosed with PD are age 60 years or older, however, an estimated 5 to 10 percent of people with PD are diagnosed before the age of 50.

This Parkinson’s Disease Awareness Month, NCIRE thanks our supported Principal Investigators, Drs. Raymond Swanson and Duygu Tosun-Turgut, for their work in PD-related research.

Learn more:
https://www.ninds.nih.gov/health-information/disorders/parkinsons-disease
https://www.parkinsons.va.gov/patients.asp

Dr. Scott R. Bauer is featured in the latest Q&A article published in the Volume 30, Spring 2026 Issue of Details News A...
04/02/2026

Dr. Scott R. Bauer is featured in the latest Q&A article published in the Volume 30, Spring 2026 Issue of Details News Awards (DNA) Newsletter, an NCIRE production:
https://www.linkedin.com/pulse/qa-dr-scott-r-bauer-ncire-7qwkf

You may read the newsletter in full on our website, www.ncire.org, under the “Resources” tab.

Scott R. Bauer, MD, MS is an Associate Professor of Medicine, Urology, Epidemiology & Biostatistics at the University of California, San Francisco and a Staff Physician with the Division of General Internal Medicine at the San Francisco VA Health Care System.

Dr. Franklin W. Huang is featured in the latest Focus on Research article published in the Volume 30, Spring 2026 Issue ...
03/30/2026

Dr. Franklin W. Huang is featured in the latest Focus on Research article published in the Volume 30, Spring 2026 Issue of Details News Awards (DNA) Newsletter, an NCIRE production: https://www.linkedin.com/pulse/focus-research-lab-drives-quest-eliminate-prostate-cancer-disparities-nhnrc

You may read the newsletter in full on our website, www.ncire.org, under the “Resources” tab.

Franklin W. Huang, MD, PhD is an Associate Professor in Residence for the Department of Medicine at the University of California, San Francisco (UCSF), and is the Principal Investigator for the San Francisco VA Health Care System/UCSF Precision Oncology Center of Excellence.

March 29th marks the date that the last combat troops left South Vietnam, the beginning of the end of America’s involvem...
03/29/2026

March 29th marks the date that the last combat troops left South Vietnam, the beginning of the end of America’s involvement in the Vietnam War.

On National Vietnam War Veterans Day, NCIRE honors Vietnam Veterans and their families for their service and remembers the men and women who put the lives of others ahead of their own to serve during one of America’s longest foreign wars.

On Medal of Honor Day, NCIRE honors those who have received the highest award for military valor in Action for distingui...
03/25/2026

On Medal of Honor Day, NCIRE honors those who have received the highest award for military valor in Action for distinguishing themselves “conspicuously by gallantry and intrepidity at the risk of their life above and beyond the call duty.”

As of early 2026, 3,547 service members received the Medal of Honor, since the first Medal of Honor presentation on March 25, 1863, to the Andrew Raiders, a cadre who showed the values of courage, commitment, sacrifice, integrity, and patriotism which are still important to Recipients of the Medal of Honor today.

On this Medal of Honor Day, NCIRE pays tribute to the brave service members recognized for their selfless acts to protect and serve their country. We salute your service and sacrifice.

Learn more: https://www.cmohs.org/

A Cluster Randomized Trial of a Vaccination Communication Educational Intervention: Impact on COVID-19 Vaccine Uptake in...
03/17/2026

A Cluster Randomized Trial of a Vaccination Communication Educational Intervention: Impact on COVID-19 Vaccine Uptake in Veterans

Despite its safety and effectiveness, COVID-19 vaccine uptake declined later in the pandemic.

In a study co-authored by Board Member Dr. Karen Seal, and Drs. Jennifer K. Manuel; Natalie Purcell and Brian Borsari, researchers evaluated the effectiveness of a Motivational Interviewing (MI)-informed educational intervention for healthcare providers and staff on vaccination communication. They hypothesized that educating providers and staff about non-judgmental, collaborative discussions would enhance vaccine uptake in Veterans.

Read more: https://link.springer.com/article/10.1007/s11606-026-10209-9

Chronic kidney disease (CKD) is a major and growing global health challenge, affecting 1 in 10 people worldwide.Often si...
03/12/2026

Chronic kidney disease (CKD) is a major and growing global health challenge, affecting 1 in 10 people worldwide.

Often silent in its early stages, CKD can progress unnoticed until it causes severe health consequences, profoundly impacting individuals, families, and communities. The disease significantly increases the risk of cardiovascular complications, reduces quality of life, and may advance to kidney failure. Its burden is unevenly distributed, disproportionately affecting disadvantaged populations and exacerbating existing health inequities.

Screening for CKD in individuals with diabetes, high blood sugar or heart disease using a simple blood test for eGFR and urine sample for urine albumin is critical in early disease detection and initiation of life-saving therapies.

The international kidney guideline organization Kidney Disease Improving Global Outcomes (KDIGO) released the 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease, authored by NCIRE Board Chair, and co-founder/co-director of the Kidney Health Research Collaborative (KHRC), Dr. Michael Shlipak. To read this and other kidney health-related guidelines, visit https://kdigo.org/

Additional resources for patients and their providers are available through www.kidney.org

The National Kidney Foundation, soon to be led by pre-elect Dr. Michelle Estrella in October 2026, is working closely with the Veterans Health Administration National Kidney Program to improve kidney care delivery for Veterans.

NCIRE thanks the Research Community for their efforts to treat and prevent worldwide.



Learn more:
https://khrc.ucsf.edu

https://www.worldkidneyday.org/2026-campaign/

Large-Scale Proteomic Profiling of Incident Heart Failure and Its Subtypes in Older AdultsHeart failure and its main sub...
03/11/2026

Large-Scale Proteomic Profiling of Incident Heart Failure and Its Subtypes in Older Adults

Heart failure and its main subtypes, heart failure with preserved ejection fraction and heart failure with reduced ejection fraction, impose an enormous health burden on elders. Assessment of the circulating proteins to illuminate the development of heart failure could open new opportunities for treatment.

The researchers identified and replicated 55 novel protein markers of heart failure or its subtypes, and 7 new, possibly causal proteins. These proteins may enhance risk prediction, improve understanding of pathobiology, and help prioritize targets for therapeutic development of these foremost disorders in elders.

Dr. Jorge Kizer co-published the study titled “Large-Scale Proteomic Profiling of Incident Heart Failure and Its Subtypes in Older Adults”.

Read more: https://www.ahajournals.org/doi/10.1161/CIRCGEN.124.005031

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Through new technologies, novel scientific insights, and international clinical collaborations, we strive to set a new standard of health care for veterans and military personnel.