02/26/2026
Sometimes gene variations can result in babies with facial differences such as a cleft lip or cleft palate. UCSF scientists are working to understand why some facial tissues don’t fuse properly during development, with the goal of one day preventing painful surgeries for newborns.
Slide 1 image shows three facial tissues in a mouse embryo fusing to form the nose and upper lip.
Slide 2 image shows a properly fused upper lip (left) compared with a cleft lip caused by failed tissue fusion (right).