OneSkin

Skin longevity science powered by OS-01, the peptide scientifically proven to reverse skin aging. We use data-driven science to achieve revolutionary products.

Sound science is only performed if based on integrity, courage to break paradigms, collaboration and trust. Those values are in our DNA, guiding everything we do.

01/14/2026

Longevity isn’t a hack. It’s a hierarchy. Here’s your skincare longevity pyramid 🔬

TIER 1 | Non-negotiable base
Show up every day: apply your skincare routine, drink plenty of water, prioritize sleep, and protect with SPF. These basics quietly account for ~80% of your long-term skin success.

TIER 2 | Cellular core
Next comes your longevity layer. Each OS-01 application sends the same signal: repair damaged cells, build more collagen, and strengthen the skin barrier.* With consistency, the signal gets stronger—and benefits add up.

TIER 3 | Precision upgrades
The refinement zone: in-office treatments such as lasers and microneedling, plus at-home actives such as retinols, secondary acids (AHA/BHA, peels), and brightening antioxidant boosters can smooth, clarify, and even tone on top of that foundation.

TIER 4 | Peak payoff
Over time, the stack shows up as resilient, firm skin that behaves like it has a bigger reserve of health.
The takeaway: if you want long-term results, don’t start at the summit. Build the base, then let consistent, science-backed layers do what they do best.

Which tier are you focusing on right now?

*Explore more at oneskin.co/claims

01/13/2026

Consistency is the chemistry.

🧪 OS-01 works behind the scene (below the surface) to reduce dysfunctional cells and reinforce your barrier. As your turnover cycle does its job, texture, elasticity, and tone follow.

Think 4–12 weeks, not overnight.

Save this as your patience plan. ⏱️

01/12/2026

The CDC puts it at 77.5, but at One Skin, we’re all about pushing past the average. We aren’t just looking at that number—we’re looking at the quality of the seasons it represents.

To our Chief Science Officer & Founder, Alessandra, longevity isn’t just a data point in a lab — it’s the ability to stay in the game. It’s about ensuring that by the time you reach winter #80, you aren’t just watching from the sidelines; you’re still catching the first chair.

She’s currently field-testing the science of healthspan at 10,000 feet. Because what’s the point of a long life if you aren’t healthy enough to enjoy the powder? ⛷️🧪

01/09/2026

Aging on your own terms 🧬 At One Skin, we believe longevity is a lifestyle. From the lab to your morning run, we are dedicated to developing the science that keeps you moving, glowing, and feeling like your best self at every age.

01/08/2026

Order = outcome.

Small-molecule serums need a clear lane first; eye/spot care comes next; moisturizer locks it in; and SPF guards the work you just did.
The takeaway: Thin to thick, treatment to protection. Make every drop work harder for cellular longevity.

Swipe to follow the flow. Save + share with a friend who (might) stack out of order.

01/07/2026

The smartest, most essential investment you can make this year.

01/06/2026

Opting out of the whole ‘new year, new me’ thing this year? One smart swap is all you need. OS-01 FACE promotes collagen and barrier strength with daily use for results you can see now and decades from now. Start a subscription for up to 25% off your first 3 shipments!

01/05/2026

12/24/2025

The most meaningful presents aren’t something to open, they’re the actions you take now to fuel your future-self’s best life. Healthy cells = more healthy years. Wishing you good health today, and in all the years ahead.

Happy holidays from the OneSkin team 🤍

12/23/2025

Give your lips a holiday break ❄️✨

Between the cold air and the holiday hustle, your lips take a beating. While you’re wrapping the final few gifts, let the OS-01 LIP Mask do the work at a cellular level.

Swipe to see how 12 weeks of OS-01 Peptide™ transforms volume and texture. It’s not just a gloss; it’s a long-term longevity practice. 🧬

12/22/2025

When shipping can’t save you, a OneSkin digital gift card will. Buy it now, have it delivered instantly. You’re welcome.

12/19/2025

Your daily dish for winter vitality is served.

Winter can be a tax on our energy and our skin. To help you thrive through the coldest months, we’re sharing our Short-Day Survival Menu — a collection of high-impact habits that pay compounding returns on your healthspan.

From circadian defense in the morning to a mindset dose before bed, longevity isn’t just about what you apply — it’s how you live.

What habits are you leaning on in this season? Let us know below 👇

Address

953 Indiana Street
San Francisco, CA
94107

Website

http://www.oneskin.co/

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Who We Are

OneSkin’s Values

We believe in data-driven science to develop products that will set a new standard when it comes to skincare and longevity. Our scientific process and operations are based on four core beliefs: integrity, courage, collaboration, and trust. These values are in our DNA, guiding everything we do.

OneSkin’s Story

Motivated by a passion to translate science into technology that will positively impact humanity, our founding team noticed that by preventing or reversing aging we can be more efficient in promoting health instead of trying to target specific diseases, that most of the times, are associated with the aging process.