02/18/2026
People living with Parkinson’s often experience problems with walking that fluctuate as they go about their everyday activities.
In a new Science Advances study, UCSF Health neurosurgeon Doris Wang, MD, PhD and her team showed for the first time that brain activity recorded from fully implanted DBS devices while patients are at home can be used to reliably determine whether a person is walking or not.
The findings are an important step towards developing improved DBS therapy to address one of Parkinson’s most disabling symptoms.
“We identified personalized neural biomarkers associated with gait and demonstrated that these signals can be used for real-time movement state classification within the constraints of an implanted device,” Wang said. “This establishes a framework for future adaptive DBS systems that could adjust stimulation in response to a patient’s activity state.”
Learn more about the research here: https://www.ucsf.edu/news/2026/02/431491/decoding-parkinsons-patients-movements-real-world