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Excedr is a founder-friendly lab equipment leasing company supporting life science startups since 2011 through equipment leasing, a non-dilutive form of capital.

"You have to balance ‘go with the flow’ with checking in and making sure that's really what you want to do… don't let in...
11/24/2025

"You have to balance ‘go with the flow’ with checking in and making sure that's really what you want to do… don't let inertia just take you down a certain path just because that's what presented itself."

We’re revisiting some of our previous episodes over the holidays this year. Our first rerelease is Part 1 of The Biotech Startups Podcast conversation with K2 HealthVentures CEO & Founding Managing Director, Parag Shah, a big theme is navigating intentional career pivots while staying open to unexpected opportunities.

In this episode, we cover:

– Growing up in NYC with parents who encouraged experimentation and healthy risk-taking, laying the foundation for an entrepreneurial mindset

– MIT's trial-by-fire education, learning to thrive in uncertainty, and discovering that struggling builds the confidence and persistence needed for entrepreneurship

– Transitioning from molecular biology research to finance, finding a serendipitous entry into credit through Bank Boston's training program in Buenos Aires

– Building Imperial Bank's life sciences practice from scratch by having the confidence to "put it out there" even without knowing everything, and learning to fail fast while extracting valuable lessons

– Translating traditional credit principles to venture debt for biotech companies, providing less dilutive capital alongside equity to help companies reach critical value inflection points

It's a fascinating journey that shows how diverse experiences in science, policy, and finance can converge into a unique career path.

Head over to Apple Podcasts or Spotify for this episode and more stories only a biotech exec can tell!

"We really want to contribute to staking longevity as a data-driven, evidence-based field and help combat all this snake...
11/20/2025

"We really want to contribute to staking longevity as a data-driven, evidence-based field and help combat all this snake oil that is out there."

In Part 4 of The Biotech Startups Podcast, LongeVC Managing Partner, Sergey Jakimov, shares his vision for transforming longevity investing through science-first principles and making the field accessible to the broader capital markets.​

Here's what we cover in this episode:

– Fundraising from limited partners (LPs) and why they tell stories instead of selling—authenticity over pitching, and attracting like-minded investors who share the mission​

– The realities of raising a first-time fund with 30% GP capital commitment, building trust without a track record, and achieving 3x returns in three years in a challenging market​

– Why good science always raises money and good companies always get acquired—how big pharma's patent cliffs, massive liquidity pools, and urgency to replenish pipelines create opportunities for venture-backed innovation​

– Making longevity investing accessible to generalist capital by translating complex science into universally understandable success stories and building an evidence-driven field that combats questionable supplements and harmful therapies​

– The critical importance of team, being "the dumbest in the room," and why individuals are evaluated by the added value they create for society​

It's a fascinating deep dive into the intersection of venture capital, longevity science, and building for long-term impact.

Head over to Apple Podcasts or Spotify for this episode and more stories only a biotech exec can tell!

"For us, longevity is prolonging health span, not lifespan. Lifespan is just a consequence. You need a life worth living...
11/17/2025

"For us, longevity is prolonging health span, not lifespan. Lifespan is just a consequence. You need a life worth living longer to begin with."

In part 3 of The Biotech Startups Podcast conversation with LongeVC Managing Partner, Sergey Jakimov, a central theme is redefining longevity investing through a science-first, patient-centered lens.

In this episode, we cover:

– Why LongeVC chose a disease-by-disease approach over "curing aging," and how that pragmatic strategy led to 20 companies with zero write-offs in 3.5 years

– How Sergey's personal experience with a rare neurodegenerative condition at 28 shifted his investment philosophy to prioritize patient outcomes over financial returns

– The challenge of translating aging biology into FDA-approved therapies, and why longevity companies must learn to speak the regulator's language

– Building a fund with scientific excellence at its core—from Nobel Prize winners on the advisory board to allocating all management fees toward team expertise instead of partner salaries

– Expanding beyond human health with AniVC for animal aging research, and launching the Longevity Science Foundation to support fundamental aging biology before it becomes investable

It's a powerful conversation about mission-driven investing, personal stakes in biotech, and building a platform where good science naturally leads to good returns.

Head over to Apple Podcasts or Spotify for this episode and more stories only a biotech exec can tell!

"Whenever you don't know anything about a specific industry, you don't have the boundaries that were imposed on you by e...
11/13/2025

"Whenever you don't know anything about a specific industry, you don't have the boundaries that were imposed on you by education or prior experience. So you don't have this automatic 'no, it cannot be done' type of situation. You kind of assume everything as a blank sheet."​

In Part 2 of The Biotech Startups Podcast conversation with LongeVC Managing Partner, Sergey Jakimov, a major theme is the power of approaching problems without preconceived limitations—and how that mindset can unlock unconventional solutions.​

Throughout this episode, Sergey and host Jon Chee explore:

– Launching his first startup at 22 with nothing to lose, entering the conservative oil and gas industry, and learning by doing rather than following traditional paths​

– The "bank heist model" of building deep tech companies: surrounding yourself with specialists who excel in specific areas, even without formal education in that field yourself​

– How you can reach a PhD-level conversation in any industry within six months when your "butt is on the line" as a founder—and why having no boundaries can be an advantage​

– Moving from medical devices to clinical data, building tools that streamline patient recruitment for pharma, and why big pharma doesn't buy capabilities—it buys outcomes​

– The value of education for developing transferable skills like research, filtering signal from noise, and disciplined thinking—even if your specific degree isn't what you end up using​

It's a fascinating look at how pattern recognition, fearless curiosity, and surrounding yourself with the right people can help you succeed across multiple industries.​

Head over to Apple Podcasts or Spotify for this episode and more stories only a biotech exec can tell!

11/12/2025

🎯 Should politicians be experts in their field BEFORE entering office, or is politics its own profession? This perspective challenges the idea of career politicians and argues for accomplished professionals giving back to society.

What do you think—should we require proven track records outside politics, or does political experience matter most? 💭

11/11/2025

🎬 From plastic bag sleds to footballs being the ultimate status symbol – this nostalgic trip through a gadget-free childhood hits different.

What was YOUR go-to toy or activity that made you the most popular kid in the neighborhood? 👇✨

11/11/2025

From concrete courts with painted lines to the top of the game 🎾💪 This is where the journey began—no fancy facilities, just pure determination and a dream at six years old.

What unconventional place did YOU first fall in love with your sport or passion? 👇✨

"The world is not big in reality, but it's very diverse. And how all these diverse cultures are going to co-live togethe...
11/10/2025

"The world is not big in reality, but it's very diverse. And how all these diverse cultures are going to co-live together and how they approach studies even differently, that was tremendous."

In Part 1 of The Biotech Startups Podcast conversation with LongeVC Founding Partner, Sergey Jakimov, a big theme is how diverse perspectives and experiences shape resilience and adaptability.

In this episode, we cover:

– Growing up in post-Soviet Latvia without technology, where constraint bred resourcefulness and outdoor childhood adventures taught survival skills

– Training under a retired national tennis coach on concrete courts, learning discipline through sport while juggling intense academic workloads and side hustles

– The transformative power of merit-based environments, from university in Riga to Central European University in Budapest, where voluntary learning replaced mandatory schooling

– Discovering that politics wasn't his calling through a disillusioning parliament internship, leading to a belief in technocracy and meritocracy over career politicians

– Experiencing true cultural diversity at CEU with students from across the globe, realizing the world is simultaneously small yet infinitely varied in approach and perspective

It's a powerful origin story about turning limitations into advantages and the value of cross-cultural learning...

Head over to Apple Podcasts or Spotify for this episode and more stories only a biotech exec can tell!

11/08/2025

"Don't worry too much" 💭 When asked what advice he'd give his 21-year-old self, this conversation with Jimmy Sastra took a deeply relatable turn about navigating life as an international student—visa deadlines, constant uncertainty, and how it shapes everything from career choices to relationships. 🌍✈️

What's one piece of advice you wish you could give your younger self? 👇

11/08/2025

🔬 Curious how cutting-edge cell culture technology is accelerating the path to curing human diseases? We're breaking down three powerful ways to work with Monomer Bio—from monitoring and data generation to full automation in your own lab. 🧬✨

Which approach would transform your research the most: in-lab software, outsourced data generation, or complete automation? Drop your thoughts below! 👇

11/07/2025

💡 Investors want you to go all-in on software and growth, but the best founders know something different: risk management is everything. 📊

In this clip, we break down the disconnect between what VCs expect (infinite scale, zero costs, 100% focus) and what founders actually need to do to survive—diversify, plan for scenarios, and manage the unknowns. 🎯

What's your take: Should founders follow the investor playbook completely, or is strategic diversification the smarter move? 👇

11/07/2025

🔥 "Fundraising is just a tool" – This conversation challenges the Silicon Valley mindset that every company needs VC backing, even in capital-intensive industries like biotech 💊

Have you ever considered bootstrapping your venture, or do you think some industries absolutely require traditional funding? Drop your thoughts below 💬

Address

100 Pine Street #1250
San Francisco, CA
94111

Telephone

+15109826552

Website

https://www.thebiotechstartupspodcast.com/

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