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The Researcher OG, Santa Barbara, CA (2025)

11/10/2025

The well-known 'Researcher OG' is calling on H**p Industry members who claim to 'care about the people' to look at their stock and hearts: dig deep, and donate ~ SANTA BARBARA, CA, UNITED STATES, November 9, 2025 /EINPresswire/ -- Mike Robinson, founder and CEO of Nanobles Corporation and the Global Cannabinoid Research Center (GCRC), has been operating a semi-large-scale Compassion Giveaway for families who have lost their SNAP food benefits. The giveaway repurposes unsold product stock from several of Robinson's trademarked h**p brands that never reached full distribution due to what he describes as "partner-related issues that were beyond my control, but none of that can stop me from the aged mission that started the industry in the first place - helping people."
This compassion campaign has already provided over 400 relief products to 175 homes, sourced from Genevieve's Dream, Researcher OG, and Researcher brands – formulations originally intended for the h**p market – to individuals and families struggling with rising food insecurity. Robinson, widely known as The Researcher OG and The Cannabis Philanthropist, emphasizes that this is not a political act but a moral one.
A Call to the Industry:
"To everyone in the h**p and cannabis space – I'm asking you to step up," said Robinson. "We've built an industry on wellness, but wellness starts with compassion. Currently, families are losing their food benefits, and they're forced to choose between putting food on the table and keeping the oils and products that provide them relief. That's a choice no one should have to make. We all have aging inventory, returns, and samples that sit on shelves – those products can change someone's life tonight. I've proven it for years; compassion always finds its way back."
The former large-scale compassion provider went on:
"This isn't about politics or profit – it's about humanity. I'm calling on every brand, every grower, every manufacturer that claims to care about people to show it. Join me in turning stock that's gathering dust into relief that matters. Let's feed both body and soul. We can make this season about giving again, not waiting for someone else to do it. If you've got product that's aging out, don't write it off – ship it out. Together, we can remind the world what this plant and this community were built on – compassion."

https://www.einpresswire.com/article/865827865/compassion-in-action-mike-robinson-revives-h**p-stock-for-families-in-snap-crisis-over-holidays

11/10/2025

A tiger is the perfect example of what it looks like to live with a finely tuned Master Regulator. Its Endocannabinoid System isn’t overactive or sluggish – it’s balanced in pure harmony with its environment. When it’s resting, every muscle relaxes, heart rate slows, and breathing deepens.
That calm isn’t laziness – it’s the ECS maintaining parasympathetic control, signaling safety. When the moment to strike comes, the tiger explodes into motion, switching instantly to fight-or-flight mode – but only when necessary.
That lightning-fast shift demonstrates the strength of its ECS balance. The tiger doesn’t live in anxiety between hunts. It doesn’t replay failure or worry about tomorrow. Its internal chemistry cycles between rest and action exactly as nature intended, because its endocannabinoids – Anandamide and 2-AG – are produced and broken down in perfect rhythm. This keeps cortisol levels low, focus sharp, and recovery fast.
Humans once operated the same way. Our ancestors possessed the same dynamic balance – calm yet ready, patient yet powerful. Today, constant stimulation, stress, and poor diet push our ECS out of sync. We stay halfway between rest and panic, never fully either. That’s what The Master Regulator is trying to correct – to bring us back to tiger mode.
CBGa, CBD, and other cannabinoids help restore that state by feeding the very system that governs balance. They allow our physiology to do what the tiger’s does naturally – rest deeply, act decisively, and recover quickly.
A tiger doesn’t force calm or chase focus – it embodies balance. That’s what happens when The Master Regulator runs the show. -Mike Robinson, The Researcher OG

11/10/2025

Before the Industrial Revolution, medicine was grounded in the Earth itself. People didn’t isolate compounds or synthesize molecules – they used whole plants. Every leaf, flower, root, and resin carried a range of bioactive compounds that worked together in ways early healers understood intuitively.

They knew the sum was greater than the parts. In ancient China, h**p and cannabis were documented as both food and medicine in The Pen Ts’ao Ching over 4,000 years ago. The plant was brewed in teas, pressed into oils, and ground into pastes to ease pain, reduce inflammation, and calm the mind.

Egyptian physicians wrote of cannabis and blue lotus used together to quiet anxiety and ease childbirth. Across India, Ayurveda utilizes the whole plant – not just cannabinoids, but also terpenes, flavonoids, and chlorophyll – as part of a larger system of body balance. Cannabis wasn’t treated as a “drug.” It was a plant ally.

The Greeks mixed cannabis seeds in wine to treat earaches. The Romans extracted resin for wound care. Native cultures burned or steeped it to treat swelling or spiritual distress. None of these uses separated CBD from THC or filtered out terpenes – the medicine was always whole. The plant’s natural ratios spoke to the body’s chemistry, and the Endocannabinoid System responded in kind.

The Industrial Revolution changed everything. Standardization and profit replaced herbal knowledge with chemistry labs and patents. Molecules were extracted from plants and synthesized, losing the entourage effect that nature had created. The world began isolating active ingredients while forgetting how the rest of the plant supported the body’s Master Regulator – the Endocannabinoid System.

Today, we’re circling back. Modern science is validating what ancient medicine practiced – that whole-plant synergy works because it speaks the same biochemical language as our ECS. Cannabis is a reminder that before industry, medicine was grown, not manufactured – and that true healing still begins in the soil.

-Mike Robinson, The Researcher OG

11/10/2025

Sample Preparation Techniques for Analysis of Endocannabinoids in Biological Fluids and Tissues" This is exciting research on the ECS that was just published on Monday 12/2/2024. It explores how scientists prepare biological samples, such as blood or tissue, to measure 2-AG and other endocannabinoids—natural compounds your body produces to help maintain balance or homeostasis. To do this, researchers need to extract and isolate these compounds in accurate and environmentally friendly ways. The goal is to ensure reliable results when analyzing these vital molecules.

The research compared several extraction methods. Traditional techniques, such as liquid-liquid extraction and protein precipitation, have been widely used but may only sometimes meet modern speed, sensitivity, or environmental sustainability needs. On the other hand, newer approaches offer faster, more eco-friendly options while allowing scientists to detect even tiny amounts of endocannabinoids. Another method explored was micro-solid phase extraction (µ-SPE), a miniaturized and efficient version of traditional solid-phase extraction.

A key focus of the study was on 2-AG, one of the most significant endocannabinoids. Measuring 2-AG is challenging because it can easily transform into a similar compound, 1-AG, and tends to degrade quickly. This instability makes it tricky to measure accurately. The researchers emphasize the importance of choosing the right extraction and analysis techniques to avoid errors, as inaccuracies could lead to flawed conclusions in scientific studies.

By continually improving how these compounds are measured in a quest to use the ECS as a target in medicine, scientists gain better insights into the endocannabinoid system and its role in maintaining health. For consumers, this means more reliable research and the potential for new advancements in understanding how your body achieves balance through its endocannabinoid system.

-Mike Robinson, founder Global Cannabinoid Research Center, The Researcher OG **pMyMedicine

11/10/2025

Sensory overload in Autism isn’t just a “bad reaction” to sound, light, or touch – it’s the nervous system overwhelmed by too much incoming data. The Master Regulator, or Endocannabinoid System, plays a key role in controlling that sensory traffic. When it’s unbalanced, signals flood the brain unchecked.

Cannabidiol, or CBD, helps restore that balance by acting on serotonin and vanilloid receptors, both of which regulate how we process sensory input and emotional responses. A 2019 study titled “Cannabidiol Regulates Emotional Response and Sensory Processing Through 5-HT1A and TRPV1 Receptors” revealed that CBD modulates neuronal hyperactivity, calming overstimulation without sedation.

CBGa works upstream, where the story begins. It’s the “mother” compound of all cannabinoids – the biochemical starter that drives cellular balance. Unlike CBD, which modulates active receptors, CBGa helps the body create the conditions for balance. It stimulates mitochondrial health, improves cellular energy transfer, and encourages endocannabinoid tone.

In individuals with Autism, that means better cellular communication, reduced neuroinflammation, and more stable signaling through the vagus nerve, which connects the gut, heart, and brain. CBGa also promotes the regeneration of endocannabinoid receptors that may have become dormant due to chronic overstimulation or stress.

Then there’s CBDa – the raw, unheated form of CBD. It’s potent in its own way, working as a selective COX-2 inhibitor, which means it reduces inflammation and serotonin dysregulation simultaneously. Studies show it boosts serotonin receptor activity even more than CBD itself.

That’s why raw h**p extracts can have a more immediate calming effect on those prone to sensory meltdowns or emotional distress.

When these three – CBD, CBDa, and CBGa – are used together, they don’t fight for space. They build harmony. CBD calms sensory chaos, CBDa fine-tunes emotional balance, and CBGa strengthens the system that keeps all signals flowing right. That’s The Master Regulator at work, balancing the inside world so the outside world feels less intense.

-Mike Robinson, The Researcher OG

11/10/2025

Hormonal imbalance isn't just about one gland or one hormone – it's about communication breakdown between the brain, glands, and organs. The Master Regulator, known as the Endocannabinoid System (ECS), is at the center of that conversation. It links the hypothalamus, pituitary, and peripheral glands – the entire hormonal command chain – ensuring messages get delivered and corrected in real time.

When the ECS is out of tune, hormone rhythms shift. Cortisol spikes too high, estrogen and progesterone fall out of balance, thyroid function dips, and sleep and metabolism suffer. Cannabis helps by restoring that communication.

A 2018 review titled "Endocannabinoid Control of the Hypothalamic–Pituitary–Gonadal Axis: Implications for Reproduction and Hormonal Health" demonstrated how endocannabinoids and plant cannabinoids directly influence hormone release. CB1 receptors in the hypothalamus and pituitary gland modulate the secretion of gonadotropin, prolactin, growth hormone, and cortisol.

In people with hormonal chaos, cannabinoids act like a signal stabilizer – calming overactive circuits while activating sluggish ones.
THC, for example, mimics the body's own endocannabinoid anandamide, providing short-term relief from stress and tension that suppress healthy hormone production.

CBD, on the other hand, supports endocannabinoid tone by preventing the breakdown of anandamide, thereby providing the body with more of its natural balancing molecule. CBG and CBGA go deeper – they interact with receptor sites beyond CB1 and CB2, including PPAR and TRP channels, both of which are known to influence insulin sensitivity, estrogen regulation, and thyroid function.

When the ECS tone is low, hormonal messages misfire. That's why many people using cannabinoids notice steadier cycles, better sleep, and reduced PMS or menopausal discomfort. Cannabis isn't replacing hormones – it's helping the body remember how to regulate them. The ECS governs homeostasis, ensuring internal harmony regardless of external disturbances.

Hormonal imbalance can look like fatigue, anxiety, weight shifts, or mood swings – all signs that the Master Regulator is overwhelmed. When endocannabinoids restore their tone, hormone communication returns to a rhythm, metabolism stabilizes, and emotional states become more balanced.

The goal isn't to flood the system – it's to guide it back to its natural pattern. Balance the ECS, and the hormones follow.

-Mike Robinson, The Researcher OG

11/09/2025

CBG – cannabigerol – is one of the most overlooked yet powerful cannabinoids for bladder health. While most people are familiar with it for its role in mood balance or gut function, research indicates that it has a significant anti-inflammatory effect on the urinary system, particularly in conditions where pain, urgency, or inflammation prevail. The bladder's walls are packed with cannabinoid receptors, meaning it's directly wired to the Master Regulator – the Endocannabinoid System (ECS).

When those receptors are activated properly, the bladder can relax, heal, and function normally again. A 2015 study titled "Cannabinoid Receptors and the Urinary Bladder," published in Nature Reviews Urology, highlighted how CB1 and CB2 receptors influence bladder contractility and pain sensitivity.

When these receptors are underactive, inflammation flares, muscle tone increases, and individuals experience symptoms similar to those of interstitial cystitis or an overactive bladder. CBG's mild affinity for both receptors makes it ideal – it doesn't overstimulate, it restores tone.

CBG also works through other cellular pathways. It's known to inhibit inflammatory enzymes, such as COX-2, and reduce nitric oxide production, both of which contribute to bladder wall irritation and pelvic pain.

A 2019 paper titled "Cannabigerol Exerts Anti-Inflammatory Effects in Bladder Epithelium via PPAR Activation" demonstrated how CBG protected epithelial cells from cytokine-induced damage while promoting barrier repair. This is crucial because chronic inflammation weakens the bladder lining, leading to pain, frequency, and sometimes infection.

Through the ECS, CBG calms nerve overactivity in the bladder's detrusor muscle – the same muscle responsible for contractions during urination. By lowering excitatory signaling, it helps reduce urgency and nighttime urination, allowing the bladder to rest and recover. The effect isn't sedation – it's signal stabilization.

When the ECS is balanced, the bladder communicates properly with the nervous system, keeping inflammation in check and maintaining smooth function. CBG restores that balance by targeting both the neural and immune components of bladder health.
For anyone dealing with bladder pain, urgency, or inflammation, CBG represents more than symptom relief – it's molecular repair through the body's own regulatory system.
-Mike Robinson, The Researcher OG

11/09/2025

CBGA’s role in thyroid health runs deeper than most realize. The thyroid gland isn’t just a hormone factory – it’s a precision instrument guided by the Master Regulator, the Endocannabinoid System (ECS). When that system’s tone is off, thyroid signaling often follows. Fatigue, weight shifts, mood swings, or temperature sensitivity can all trace back to miscommunication between the ECS and the hypothalamic-pituitary-thyroid (HPT) axis.

A 2018 review titled The Endocannabinoid System and Thyroid Hormones: Implications for Energy Balance detailed how endocannabinoids like anandamide influence thyroid hormone release through CB1 receptors in the hypothalamus and pituitary. When those receptors are over- or under-stimulated, thyroid output can fluctuate, resulting in either hypo- or hyper-like symptoms.

The ECS acts as the body’s thermostat for hormones, metabolism, and temperature regulation.

CBGA, the acidic “mother” cannabinoid, adds a unique layer of support. Unlike THC or CBD, it doesn’t overstimulate CB1 or CB2 receptors. Instead, it modulates them indirectly and interacts with PPAR-alpha receptors – key regulators of lipid metabolism and inflammation inside thyroid tissue.

A 2021 study titled PPAR Activation by Cannabigerolic Acid: Implications for Metabolic Disorders demonstrated that CBGA’s interaction with these receptors helped restore lipid and glucose balance in cell models. Since thyroid health is deeply tied to metabolic stability, this connection matters.

Chronic inflammation, oxidative stress, and immune overactivity are common triggers for thyroid dysfunction. CBGA’s antioxidant and anti-inflammatory effects protect thyroid cells from the oxidative strain that can lead to autoimmune issues like Hashimoto’s or Graves’. By reducing reactive oxygen species and supporting mitochondrial health, CBGA helps the gland maintain its rhythm without overworking.

So while traditional medicine often treats thyroid symptoms at the hormonal level, CBGA works one step upstream – helping the ECS coordinate thyroid signaling from the inside out. Balance the Master Regulator, and hormone balance follows.

-Mike Robinson, The Researcher OG

11/08/2025

Restless Legs Syndrome isn't just about twitching limbs – it's about misfired dopamine signaling and restless neurons that can't find rhythm. Deep inside that pattern lies the Endocannabinoid System, the Master Regulator that governs neurotransmitter flow and maintains balance in movement, mood, and rest. When dopamine pathways in the basal ganglia fire irregularly, the ECS steps in to calm them – and that's where CBN shows promise.

CBN, or cannabinol, is a mildly psychoactive cannabinoid formed as THC ages and oxidizes. But unlike THC, it doesn't overstimulate receptors; it soothes them. A 2020 review titled "Cannabinoids and Sleep: A Review of the Literature" noted that CBN interacts with CB1 receptors in a low-affinity but stabilizing manner, meaning it doesn't flood the system – it fine-tunes it.

In conditions like Restless Legs Syndrome, where dopamine surges unpredictably during rest, this subtle modulation can restore signal timing.
The ECS has direct links with dopaminergic neurons. Endocannabinoids, like anandamide, regulate dopamine release in the striatum – the same region involved in movement control.

When ECS tone is low, dopamine spikes go unchecked, leading to muscle twitches and that crawling urge to move. CBN supports the ECS by slowing neurotransmitter release, enhancing GABAergic inhibition, and easing excitatory overload.

The effect is a calmer neuronal field, where dopamine can pulse at the proper rhythm instead of stuttering through the night. CBN's role extends to sleep onset and muscle relaxation. By engaging CB2 and TRPV2 channels, it reduces inflammation in peripheral nerves, another factor tied to RLS discomfort. It doesn't sedate in the traditional sense – it balances. This is why people describe deeper rest rather than heavy drowsiness.

Restless Legs Syndrome isn't always a dopamine disorder – it's often a signaling imbalance where the Master Regulator is off-key. By helping the ECS regain tone, CBN encourages smooth neurotransmission, steadier dopamine flow, and a quieter body. It's not about numbing the legs – it's about letting the signals sync again.

-Mike Robinson, The Researcher OG

11/08/2025

CBGA is often called the “mother cannabinoid,” but what it really does is act like a molecular coach for your cells – especially the mitochondria, those tiny engines that power everything you do. Mitochondria make ATP, the fuel that keeps your body running, but they’re also sensitive to stress, toxins, and inflammation.

When they struggle, energy levels drop, oxidative stress increases, and disease risk rises. That’s where CBGA steps in. A 2021 study titled Cannabigerolic Acid Protects Mitochondrial Function and Reduces Oxidative Stress in Neuronal Cells showed that CBGA helps preserve mitochondrial membrane potential – the electrical charge that allows ATP to form efficiently.

When cells are under oxidative stress, CBGA reduces reactive oxygen species, assisting mitochondria to remain stable. Think of it like reinforcing the walls of an overworked factory before it burns out.

The Endocannabinoid System – the Master Regulator – oversees mitochondrial balance by managing calcium flow, metabolic rate, and redox state inside cells. CBGA supports that role by enhancing the body’s own endocannabinoid tone. It doesn’t just act on CB1 or CB2 receptors – it influences PPAR receptors and TRP channels, both of which control how mitochondria use oxygen and handle inflammation. The result is cleaner energy output and less cellular waste.

When mitochondria function properly, everything else follows – mood, metabolism, focus, and immune strength. But when they’re overloaded or underpowered, the ECS compensates by sending signals that can lead to fatigue, pain, or brain fog. CBGA’s antioxidant and bioenergetic effects help the Master Regulator restore communication between the nucleus and mitochondria, allowing cells to adapt instead of collapsing.

That’s why CBGA fits perfectly into the concept of ECS Balance Control – it’s not just about cannabinoids and receptors, it’s about how every cell produces, uses, and protects its own energy. By supporting mitochondrial function, CBGA helps maintain the internal rhythm that keeps life steady, one molecule of ATP at a time.

-Mike Robinson, The Researcher OG

11/08/2025

Cannabinoids and endocannabinoids aren’t just molecules floating around – they’re cellular signalers, the messengers that tell your body how to respond, repair, and relax. Every time a nerve fires, a hormone is released, or an immune cell reacts, signals are moving cell to cell in a language composed of molecules. The Endocannabinoid System – the Master Regulator – uses cannabinoids as part of that language to keep every message in tune.

Endocannabinoids, such as anandamide (AEA) and 2-arachidonoylglycerol (2-AG), are produced and localized within cells. They don’t sit waiting in storage like neurotransmitters – they’re created when the body senses imbalance.

Once released, they bind to receptors such as CB1 in the brain and CB2 in immune tissue, instructing cells to slow down or change direction. They’re the internal moderators keeping cellular conversations from turning into shouting matches.

Plant cannabinoids work the same way – they join the dialogue. CBD, CBG, and CBGA don’t force cells to act; they fine-tune how messages are received. For example, CBD can prevent excessive breakdown of anandamide, extending its calming influence. CBGA, known as the “mother cannabinoid,” interacts upstream, helping maintain receptor sensitivity and encouraging the body to generate more of its own endocannabinoids when needed.

A 2018 paper titled Endocannabinoid Signaling in Health and Disease explained how these lipid messengers regulate neurotransmission, inflammation, and energy balance at the cellular level. When the ECS is functioning properly, cells communicate efficiently, adjusting metabolism, immune activity, and mood in real-time.

When it’s off, those messages misfire – inflammation lingers, stress loops repeat, and healing slows. This is what makes cannabinoids so powerful: they don’t override biology – they help it communicate.

By restoring signal flow, they guide the body back toward balance instead of forcing change. Each signal strengthens harmony across systems – the brain, gut, immune, and endocrine systems – all linked through the Master Regulator’s network.

Every cell in your body is talking. Cannabinoids help make the conversation sense again.

-Mike Robinson, The Researcher OG

11/08/2025

The Master Regulator – the Endocannabinoid System – runs differently in every human being, and that’s what makes it so fascinating. It’s not one-size-fits-all. Your ECS depends on the right mix of cannabinoids and endocannabinoids to stay balanced, but what’s “right” for you might be wrong for someone else. This is why cannabis affects everyone differently, and why one strain or ratio can bring peace to one person and panic to another.

The ECS relies on constant feedback between receptors, enzymes, and signaling molecules to maintain a stable internal environment. CB1 receptors manage brain and nervous system activity. In contrast, CB2 receptors guide immune response and inflammation.

Endocannabinoids, such as anandamide and 2-AG, are the messengers that signal to those receptors when to activate or rest. When the messages get scrambled – by stress, diet, or excess THC – the system goes off balance, and symptoms appear.

A 2017 review titled Endocannabinoid System Dysfunction and Its Role in Mood and Stress Regulation showed how overstimulation of CB1 receptors from too much THC can desensitize them, reducing natural endocannabinoid signaling. That’s when users start chasing effects that don’t hit like they used to, or develop anxiety, irritability, or even insomnia instead of relief. The body’s not broken – the ECS is asking for recalibration.

This is where other cannabinoids step in. Compounds like CBD, CBG, CBC, and especially CBGA help restore tone by indirectly supporting receptor sensitivity and enzyme balance. CBGA acts upstream – feeding the system with precursors to make what it needs, rather than flooding it with more signals. Think of it as giving the ECS ingredients instead of instructions.

When people learn their personal cannabinoid profile – what supports their system versus what overwhelms it – they move closer to real balance. That’s the essence of ECS medicine: self-awareness meets molecular precision.

Too much THC can cloud the conversation between your body and brain, but the right cannabinoids can open that channel again. The Master Regulator doesn’t need excess – it needs harmony.

-Mike Robinson, The Researcher OG

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