Spekr, Santa Mon, CA (2025)

05/29/2023

This 2018 study aimed to investigate the pharmacokinetics of CBD in healthy dogs using three different formulations: oral microencapsulated oil beads, oral CBD-infused oil, and CBD-infused transdermal cream.

The findings of this randomized controlled trial refute a popular industry belief that topical or microencapsulation product formulations can somehow result in the highest CBD absorption.

Instead, the study once again validates the high standards of a small minority of formulation scientists in the industry who prioritize scientific evidence, efficiency, and optimal health over new popular marketing trends like these unnecessary microencapsulated oral technologies.

As confirmed by other studies, the regular oral CBD-infused oil formulation demonstrated the most favorable pharmacokinetic profile, exhibiting higher maximal concentrations and systemic exposure compared to the other two formulations.

The participants took doses of 75mg or 150mg CBD every 12 hours for six weeks. The exposure was dose-proportional, and oral CBD-infused oil provided the most favorable pharmacokinetic profile.

The researchers originally hypothesized that the transdermal cream route of administration would be more effective in delivering CBD due to its avoidance of first-pass effect from the liver, which typically reduces the bioavailability of orally administered CBD in both and humans.

However, in this study, what has already been known by some in the industry was confirmed that the CBD-infused transdermal cream did not reach similar plasma concentrations as the other 2 oral formulations.

Contrary to popular belief in the industry that microencapsulated or topical versions of CBD absorb better than regular oral CBD oil, this study provides more scientific evidence that oral CBD-infused oil is actually superior in absorption.

This highlights the importance of conducting rigorous independent research and not relying solely on industry claims when making decisions about purchasing products.

These findings suggest that the oral CBD-infused oil formulation is the most superior option for the best absorption of CBD in dogs.

05/09/2023

This 2018 randomized controlled trial aimed to investigate the pharmacokinetics of CBD in healthy dogs using three different formulations (oral microencapsulated CBD oil beads, oral CBD-infused oil, and CBD-infused transdermal cream) every 12 hours for six weeks.

The study results showed that the oral CBD-infused oil formulation provided the most favorable pharmacokinetic profile, with higher maximal concentrations and systemic exposure than the other two formulations.

Additionally, the CBD-infused oil formulation had the smallest amount of inter-individual variability in plasma concentrations.

In contrast, the CBD-infused transdermal cream did not reach similar plasma concentrations as the other two formulations, likely due to diffusion barriers such as the thickness of the pinnae skin or the absorptivity of the cream.

Thirty healthy adult male beagle , from 4 to 5 years of age, were randomly assigned to 1 of 3 CBD delivery methods.

The dogs were then divided into 2 different dosing groups to receive either 75mg or 150mg every 12 hours. All dogs were administered a total daily dose of either 150mg or 300mg of CBD using 1 of the following delivery methods: CBD-infused transdermal cream (110 mg/mL) applied to the pinnae; beads of microencapsulated oil in capsules (25mg and 50mg capsule sizes); or CBD-infused oil (75mg/mL or 150mg/mL).

For the duration of the study, all dogs were administered each dose of CBD after a small meal.

These findings suggest that the standard oral CBD-infused oil formulation is the most superior option for the best absorption of CBD for dogs.

Contrary to popular belief in the industry that microencapsulated or transdermal versions of CBD have better absorption than the standard oral CBD-infused oil, this study provides scientific evidence that oral CBD oil is actually superior in absorption. These findings highlight the importance of conducting rigorous independent research and not relying solely on industry claims when making decisions about CBD products.

05/06/2023

In this 2005 clinical trial, scientists explored the benefits of using skincare products enriched with Vitamin E on the skin's antioxidant protection against photooxidative stress.

The study discovered that using a product that contained alpha-tocopherol, the most biologically active form of vitamin E, had a protective effect on the skin barrier by shielding it from photooxidative stress.

This is significant because the skin barrier plays a critical role in protecting the body from environmental stressors.

In this clinical trial, 13 healthy volunteers were asked to use a vitamin E-enriched product on one forearm and a placebo product on the other for three weeks. The researchers checked the levels of and squalene on the skin before and after the study period.

They discovered that using the vitamin E-enriched product increased the levels of vitamin E and squalene significantly, while the placebo product decreased these levels.

Moreover, the study revealed that using the vitamin E-enriched product protected against UVA-induced photooxidation of squalene.

Overall, the results of this clinical trial suggest that using a skincare product with vitamin E can be beneficial for the skin's health, boosting vitamin E and squalene levels on the skin and providing antioxidant protection against harmful environmental factors.

It's important to note that not all vitamin E is created equally. There are natural and synthetic forms of vitamin E, and even the natural forms can come from questionable sources such as soy, wheat, or petroleum. This is why it's crucial to make sure you know the derivative and type of vitamin E that is used in the products you're purchasing.

05/05/2023

This 2020 randomized, double-blind, placebo-controlled, crossover clinical trial aimed at evaluating the effects of acute CBD administration on anxiety measures and tremors in individuals with Parkinson's disease.

The study found that giving Parkinson's patients a single 300mg dose of CBD reduced their anxiety levels, and also reduced tremors in situations that made them feel anxious.

A total of 24 individuals with Parkinson's disease were included in the study and underwent two experimental sessions within a 15-day interval.

The participants were given CBD at a dose of 300mg or a placebo and underwent the Simulated Public Speaking Test, where data such as heart rate, systemic blood pressure, tremor frequency, and amplitude were collected.

Giving patients with Parkinson's disease a single 300mg dose of CBD decreased anxiety and lessened tremors in anxiety-inducing situations, highlighting CBD's potential usefulness in treating these common symptoms, which can be difficult to treat with current options that often have unwanted side effects.

Therefore, the study suggests that CBD could be a promising alternative treatment for patients with Parkinson's disease and anxiety, especially given the limited therapeutic options currently available that come with side effects such as increased tremors, increased risk of falls, and worsened cognition.

05/03/2023

💪This 2014 study aimed to investigate the effects of peppermint oil ingestion on various physiological parameters and exercise performance on healthy humans.

The human study involved 30 healthy male university students and the positive results were clear.

The experimental group, who ingested oil, experienced a 36.1% increase in grip force, a 7.0% increase in vertical jump height, and a 6.4% increase in long jump distance compared to the control group.

Additionally, lung function measurements showed a 35.1% increase in forced vital capacity in the first second, a 66.4% increase in peak inspiratory flow rate, and a 65.1% increase in peak expiratory flow rate.

The experimental group also saw improvements in reaction times.

These findings suggest that peppermint oil may have a positive impact on athletic performance.

The results of this study indicate that incorporating peppermint oil into your routine could be an effective way to enhance athletic performance.

05/03/2023

💪As athletes, we are always looking for ways to improve our performance. In recent years, there has been growing interest in the use of natural supplements to enhance exercise performance, and one such supplement is peppermint oil.

This 2014 study aimed to investigate the effects of peppermint oil ingestion on various physiological parameters and exercise performance on healthy humans.

The human study involved 30 healthy male university students and the positive results were rapidly seen.

The experimental group, who ingested peppermint oil, experienced a 36.1% increase in grip force, a 7.0% increase in vertical jump height, and a 6.4% increase in long jump distance compared to the control group.

Additionally, lung function measurements showed a 35.1% increase in forced vital capacity in the first second, a 66.4% increase in peak inspiratory flow rate, and a 65.1% increase in peak expiratory flow rate.

The experimental group also saw improvements in reaction times.

These findings suggest that oil may have a positive impact on athletic performance.

This study represents a significant step forward in our understanding of the use of natural supplements to enhance athletic performance.

The results of this study indicate that incorporating into an routine could be an effective way to enhance athletic performance.🌱🏋️🤸‍♀️

05/03/2023

💪As athletes, we are always looking for ways to improve our performance. In recent years, there has been growing interest in the use of natural supplements to enhance exercise performance, and one such supplement is peppermint oil.

This 2014 study aimed to investigate the effects of peppermint oil ingestion on various physiological parameters and exercise performance on healthy humans.

The human study involved 30 healthy male university students and the positive results were rapidly seen.

The experimental group, who ingested peppermint oil, experienced a 36.1% increase in grip force, a 7.0% increase in vertical jump height, and a 6.4% increase in long jump distance compared to the control group.

Additionally, lung function measurements showed a 35.1% increase in forced vital capacity in the first second, a 66.4% increase in peak inspiratory flow rate, and a 65.1% increase in peak expiratory flow rate.

The experimental group also saw improvements in reaction times.

These findings suggest that oil may have a positive impact on athletic performance.

This study represents a significant step forward in our understanding of the use of natural supplements to enhance athletic performance.

The results of this study indicate that incorporating into an exercise routine could be an effective way to enhance athletic performance.🌱🏋️🤸‍♀️

04/22/2023

A 2018 study found MCT oil supplementation increased running endurance and improved skeletal muscle function in high temperature conditions. The study suggests that MCT supplementation may be beneficial for improving exercise capacity and muscle function, particularly under high temperature conditions.

The study involved training mice on a treadmill for 14 days under normal or high-temperature conditions. The results showed that the mice fed with MCT-containing diets had much better performance compared to the regular chow diet-fed mice.

The study also examined the levels of mRNA and protein involved in mitochondrial biogenesis, which were found to be significantly upregulated by MCT oil. The researchers concluded that MCT oil improves skeletal muscle function through the induction of mitochondrial biogenesis and metabolism under high-temperature conditions.

MCT works by increasing the number and activity of mitochondria, which are the organelles in cells that produce energy. This is achieved through the activation of two signaling pathways, Akt and AMPK.

Akt helps to regulate the uptake of glucose by cells and the sensitivity to insulin, while AMPK plays a role in regulating energy balance in cells.

The study also found that MCT may increase insulin sensitivity, glucose utilization, and energy expenditure without causing oxidative stress in skeletal muscle.

Want to read about more studies like this one? Checkout the Spekr Library at SpekrHealth.com, a valuable resource that provides comprehensive summaries of scientific studies on ingredients, health, and lifestyle.📲

04/11/2023

A 2022 toxicity study has revealed that CBD is not only non-toxic, but it may actually extend lifespan by up to 18%.

As the popularity of CBD as a natural remedy continues to grow, concerns have emerged about its potential long-term toxicity.

However, this groundbreaking study published in 2022 has debunked these fears, revealing that not only is CBD safe to use at physiologically relevant concentrations, but it may also extend lifespan by up to 18% in a commonly used model organism, Caenorhabditis elegans (roundworm).

These results add to the growing body of evidence suggesting that CBD is safe for use, and may hold significant promise as a natural compound in health and wellness. While further research is necessary to fully understand the long-term effects of CBD use in humans, this study marks a major breakthrough, providing much-needed reassurance to CBD users and advocates alike.

Want to read more studies like this one? Checkout the new Spekr Library at SpekrHealth.com, a valuable resource that provides comprehensive summaries of scientific studies on ingredients, health, and lifestyle. With this new library at your disposal, you can make more informed decisions about your health by accessing detailed and easy-to-understand information about the latest scientific research.📲

04/10/2023

A 2022 toxicity study has revealed that CBD is not only non-toxic, but it may actually extend lifespan by up to 18%.

As the popularity of CBD as a natural remedy continues to grow, concerns have emerged about its potential long-term toxicity.

However, this groundbreaking study published in 2022 has debunked these fears, revealing that not only is CBD safe to use at physiologically relevant concentrations, but it may also extend lifespan by up to 18% in a commonly used model organism, Caenorhabditis elegans.

These results add to the growing body of evidence suggesting that CBD is safe for use, and may hold significant promise as a natural compound in health and wellness. While further research is necessary to fully understand the long-term effects of CBD use in humans, this study marks a major breakthrough, providing much-needed reassurance to CBD users and advocates alike.

Want to read more studies like this one? Checkout the new Spekr Library at SpekrHealth.com, a valuable resource that provides comprehensive summaries of scientific studies on ingredients, health, and lifestyle. With this new library at your disposal, you can make more informed decisions about your health by accessing detailed and easy-to-understand information about the latest scientific research.📲

03/02/2023

Introducing the new and improved Spekr! As we enter our fifth year in business, we're thrilled to unveil our latest product launch and brand new website. We've been working tirelessly behind the scenes to create targeted products for specific uses, and we can't wait for you to try them out!

At Spekr, we're dedicated to providing you with the best natural health optimization products on the market. That's why we've spent the last year carefully formulating and testing our new product line to ensure it meets our high standards.

But that's not all! We've also completely revamped our website to make it even easier for you to learn about our ingredients and their benefits. With detailed information on each natural ingredient we use, you can feel confident in the products you're using and the positive impact they can have on your overall health and wellbeing.

At Spekr, we believe in using dynamic ingredient standards that are always evolving, not static ones. It's important for a company to always keep evolving and creating new product formulations as the times and the science evolves, and we are committed to staying ahead of the game. That's why we've been working lowkey for the last year to provide you with targeted products for specific uses, raising the standard of your user experience with Spekr.

Our new website is extremely detailed, interactive, and user-friendly, giving you exact information on each natural ingredient we source in our product formulations. We want you to know exactly what you're putting in your body and how it can benefit you. So, come and check out our new line of products and experience the Spekr difference for yourself.✌️❤️

11/29/2022

HAPPY CYBER MONDAY! Our biggest discount of the year ends soon, happening now only at our website.

Give yourself the gift of health.❤️✨

Spekr

05/29/2023

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11/29/2022

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