Pacific Neuroscience Institute

Pacific Neuroscience Institute Comprehensive Neurological Care, All in One Place, Focused on You. Our Linktree: https://shorturl.at/QIKQa We are a site for several clinical trials.

The Pacific Neuroscience Institute located at the John Wayne Cancer Institute and Providence Saint John's Health Center specializes in the treatment and care of patients with pituitary, brain and skull base tumors and other neurological disorders. Founded by Dr. Daniel Kelly, PNI emphasizes patient specific care with leading-edge minimally invasive surgical techniques and instrumentation. Our Research Center collaborates closely with scientists at the John Wayne Cancer Institute conducting research in basic science, preclinical research and translational research studies. Education is a high priority at our institute, where we train top surgical fellows in endoscopic and minimally invasive surgery. We also routinely participate in community outreach programs at local and national circles.

New research in PNAS Nexus highlights a critical link between the oral microbiome and Alzheimer’s risk.Discussing these ...
12/08/2025

New research in PNAS Nexus highlights a critical link between the oral microbiome and Alzheimer’s risk.

Discussing these findings, PNI’s Dr. Jennifer Bramen, Director of Neuroimaging, notes that while certain oral bacteria are linked to cognitive decline, others actually support memory.

The Key Takeaways:

The Connection: Higher levels of "good" bacteria (Neisseria and Haemophilus) correlate with better attention and memory retention.

The Action Plan: Dr. Bramen recommends a diet rich in nitrate-heavy vegetables to suppress harmful pathogens and support brain health.

Learn more by reading the full article here: https://shorturl.at/1oaJz

Dr. Marcus Mazur has opened a new PNI spine clinic in Santa Monica. Dr. Mazur is a highly skilled and experienced board-...
12/05/2025

Dr. Marcus Mazur has opened a new PNI spine clinic in Santa Monica. Dr. Mazur is a highly skilled and experienced board-certified fellowship-trained spine neurosurgeon.

His clinical practice focuses on adult spinal surgery for disorders of the cervical, thoracic, and lumbar spine. He is a recognized expert in the treatment of adult spinal deformity, complex revision surgery, spinal oncology, and minimally invasive spine surgery.

For patients wishing to schedule a consultation, contact us at 310-582-7450.

2125 Arizona Ave, 2nd Floor, Santa Monica, CA 90404

Join us next week on Tuesday at 12:30 PM PT for Grand Rounds.Constantinos Hadjipanayis, MD, PhD, will present on integra...
12/05/2025

Join us next week on Tuesday at 12:30 PM PT for Grand Rounds.

Constantinos Hadjipanayis, MD, PhD, will present on integrating data streams in the O.R. for brain tumor surgery with moderation by Walavan Sivakumar, MD, and Garni Barkhoudarian, MD.

This month’s Grand Rounds also offers CME credit—be sure to sign in with your full name to receive credit.

Zoom Meeting Information:

💙 Link: https://zoom.us/join

💙 Webinar ID: 895 4586 0279

💙 Passcode: 90503

New data from CREST-2 show that for people with severe carotid artery narrowing but no recent stroke symptoms, adding a ...
12/04/2025

New data from CREST-2 show that for people with severe carotid artery narrowing but no recent stroke symptoms, adding a minimally invasive stent procedure to intensive medical therapy cut stroke risk by more than half compared with medical therapy alone.

Over four years, just 2.8% of patients who received stenting + medical care experienced a stroke — versus 6.0% of those on medical treatment alone.

The results are being hailed as a milestone for stroke prevention, offering new hope for patients at high risk of carotid stenosis and strengthening the case for stenting under the right conditions.

Click the link below to learn more.

https://vascularnews.com/historical-crest-2-data-show-reduced-stroke-risk-with-carotid-stenting-versus-medical-therapy-alone/

At Pacific Neuroscience Institute, collaboration and curiosity drive every advancement in neurosurgery.In our blog, inte...
12/04/2025

At Pacific Neuroscience Institute, collaboration and curiosity drive every advancement in neurosurgery.

In our blog, international neurosurgeon observer Artur Rizer reflects on his two-month experience under the mentorship of Dr. Garni Barkhoudarian and the PNI neurosurgical team.

From morning rounds to complex skull base surgeries, he gained a firsthand look at the precision, teamwork, and dedication that define patient-centered care.

Click the link below to read the full article to learn how mentorship and hands-on learning continue to shape the next generation of neurosurgeons.

Article: https://www.pacificneuroscienceinstitute.org/blog/neuroscience-research/neurosurgery-observership-experience-precision-mentorship-at-pni/

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12/03/2025

Precision in the operating room comes from more than surgical skill. ⁠

In this PNI Minute from the Quantum Leadership Podcast, Daniel F. Kelly, MD, reflects on how great surgeons balance courage with careful decision-making—respecting anatomy, knowing limits, and centering each patient’s needs. ⁠

This clip is part of a larger conversation with host Dr. Stephen Sideroff about leadership under pressure—from building a groundbreaking neuroscience institute to performing high-stakes brain tumor surgery where every millimeter matters. ⁠⁠

🎧 Listen to this episode on your favorite podcast platform.⁠

For Giving Tuesday, Pacific Neuroscience Institute is taking a moment to reflect on the strength of our community and th...
12/02/2025

For Giving Tuesday, Pacific Neuroscience Institute is taking a moment to reflect on the strength of our community and the work accomplished in 2025.

Our December newsletter highlights key moments from the year, including Dr. Chester Griffiths’ response during the LA wildfires, along with features on the programs and physicians advancing facial nerve care, cochlear implants, and brain tumor treatment.

We invite you to explore the full edition and consider supporting neuroscience care, research, and innovation at PNI.

https://myemail.constantcontact.com/Honoring-a-Year-of-Impact-with-Gratitude.html?soid=1123998205715&aid=Ib9cuPUhg3M

An 81-year-old Alzheimer’s patient recently completed a nearly 3,000-mile walk from California to Florida — a remarkable...
12/01/2025

An 81-year-old Alzheimer’s patient recently completed a nearly 3,000-mile walk from California to Florida — a remarkable achievement that reflects years of support from Pacific Neuroscience Institute.

After her diagnosis, she began working with Dr. Dale Bredesen, whose individualized brain-health program focused on nutrition, movement, sleep, and targeted interventions to help slow cognitive decline and improve daily function.

Her cross-country finish serves as a meaningful reminder that Alzheimer’s care can promote strength, purpose, and quality of life. It highlights the ongoing need for research-driven approaches that help patients continue doing what they love.

Read the full story here: https://www.clickorlando.com/news/local/2025/11/15/81-year-old-alzheimers-survivor-finishes-nearly-3k-mile-walk-from-california-to-florida/

Today, we give thanks for our patients and families and for the dedication of our clinicians, researchers, and staff. We...
11/28/2025

Today, we give thanks for our patients and families and for the dedication of our clinicians, researchers, and staff. We’re honored to care for you—today and every day.

11/26/2025

Meningiomas are the most common primary brain tumor, and in many cases, individuals are unaware they have one until symptoms appear.

In this PNI Minute, Nouzhan Sehati, MD, explains that most meningiomas are slow-growing and benign. Because they originate from the protective layers surrounding the brain—not the brain tissue itself—surgical removal can often relieve pressure and support meaningful recovery.

Understanding diagnosis and treatment options helps patients and families make informed decisions with confidence.

🎧 Listen to this episode on your favorite podcast platform.⁠

Research presented back in April this year at the American Academy of Neurology’s 77th Annual Meeting found that individ...
11/25/2025

Research presented back in April this year at the American Academy of Neurology’s 77th Annual Meeting found that individuals who engage in moderate to vigorous daily activity are up to 40% less likely to develop dementia, depression, stroke, anxiety, or sleep disorders than those who are more sedentary.

Dr. David A. Merrill, geriatric psychiatrist and Singleton Endowed Chair in Integrative Brain Health at Pacific Neuroscience Institute, told Medical News Today:

“Even moderate levels of physical activity are linked to a lower risk of multiple neuropsychiatric conditions—from dementia to depression—highlighting just how powerful movement is for protecting the brain.”

These findings reinforce the link between physical activity and brain health, showing the importance of movement as a preventive tool across all ages. Click the link below to read the full article.

https://www.medicalnewstoday.com/articles/boosting-physical-activity-may-lower-dementia-depression-risk

At PNI, we’re grateful for many things, especially the physicians whose care brings comfort and clarity to patients ever...
11/24/2025

At PNI, we’re grateful for many things, especially the physicians whose care brings comfort and clarity to patients every day.⁠

One patient recently shared their experience with Dr. Christopher Putman, MD:⁠

“Dr. Putnam is very patient, provides clear explanations and answers to questions, and makes one feel very comfortable. I feel that Dr. Putnam is a very caring doctor, which seems rare these days.”⁠

We’re thankful for Dr. Putman’s steady presence and commitment to patient-centered care.⁠

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2125 Arizona Avenue
Santa Monica, CA
90404

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