04/08/2026
Most people think brain diseases start in the brain.
But research increasingly shows inflammation may start in the gut and diet.
Three dietary compounds are being studied for their role in neuroinflammation and cognitive decline:
• Lipopolysaccharides (LPS)
• Advanced Glycation End Products (AGEs)
• Arachidonic Acid (AA)
These compounds can activate microglia, the immune cells of the brain.
When microglia stay activated too long, they release inflammatory signals like IL-6, TNF-alpha, and IL-1β ... chemicals strongly linked with neurodegeneration and Alzheimer’s disease.
And the surprising part?
Many of these molecules come directly from the foods we eat.
In the next videos I’ll break down each one and where they show up in the diet.
Follow along if you want to protect your brain long-term.