Fred Hutch ID Sciences

Fred Hutch ID Sciences Fred Hutch Infectious Disease Sciences: Patient care and research of Infectious disease relating to cancer, HIV, and organ and stem cell transplantation.

10/17/2019

New paper from Hutch IDS team - Reported Beta Lactam and Other Antibiotic Allergies in Solid Organ and Hematopoietic Cell Transplant Recipients

Conclusion: Transplant recipients are frequently exposed to antibiotics and have a high prevalence of reported antibiotic allergies. Reported BLA was associated with greater use of beta lactam antibiotic alternatives. Pre-transplant antibiotic allergy evaluation may optimize antibiotic use in this population.

From Dr. Pergam: This is a manuscript that none of us wanted to write. However, we felt compelled due to ongoing   outbr...
08/12/2019

From Dr. Pergam:

This is a manuscript that none of us wanted to write. However, we felt compelled due to ongoing outbreaks and risk to our vulnerable patient populations. Immunosuppressed patients are at higher risk for complications - like encephalitis & pneumonia - but rely on herd immunity for protection. Many cannot get live virus vaccines like , or if previously vaccinated, have weakened immune systems put them at high risk. This paper gives a summary of what we know about measles in cancer (it isn't pretty), and what we can do to best protect our patients. It also gives guidance for when one might consider early vaccination for some of these high-risk patients.

Until recently, measles exposures were relatively rare, and so consequently, were an afterthought for cancer and/or blood and marrow transplant recipi…

Check out our newest Staff Spotlight, in which we highlight the work of a valued IDS team member. Here is Financial Anal...
02/06/2019

Check out our newest Staff Spotlight, in which we highlight the work of a valued IDS team member. Here is Financial Analyst Pascal!

HIV-infected people must take antiretroviral drugs for their entire lifetimes to control infection, because HIV can pers...
11/16/2018

HIV-infected people must take antiretroviral drugs for their entire lifetimes to control infection, because HIV can persist in infected, treated people for decades…but where? Dan Reeves, Elizabeth Duke & the Schiffer Group in HutchIDS show that proliferation of infected cells – not viral replication – is the primary driver of HIV persistence. Existing cell proliferation-blocking drugs may be a promising route to HIV cure. Out today in Nature Communications:

HIV infected cells persist for decades in patients under ART, but the mechanisms responsible remain unclear. Here, Reeves et al. use modeling approaches adapted from ecology to show that cellular proliferation, rather than viral replication, generates a majority of infected cells during ART.

Check out these avatars of our IP team, by the talented Ethan Kocak ( on Twitter)! We love them!!! 👏
11/01/2018

Check out these avatars of our IP team, by the talented Ethan Kocak ( on Twitter)! We love them!!! 👏

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