Optispan Podcast

Optispan Podcast Optispan is a vision for what healthcare should be.

Join us on a journey of discovery as we explore the science of longevity and optimal healthspan ("Optispan").

Your doctor checks 12 biomarkers at your annual physical. We check 100+.Here are 5 that most physicians don't test but s...
01/14/2026

Your doctor checks 12 biomarkers at your annual physical. We check 100+.

Here are 5 that most physicians don't test but should.

Why don't doctors check these? Because standard panels haven't evolved. Medical training lags behind the research. And insurance often doesn't cover what's not considered "standard of care."

But here's the problem: These markers reveal dysfunction years before it becomes disease. By the time standard testing catches it, you've lost years of preventive opportunity.

At Optispan, we don't wait. We track what matters and intervene early.

Swipe to learn what your doctor isn't checking. →
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01/13/2026

Most healthcare only looks at lab numbers. We look inside your body.
Point-of-care ultrasound (POCUS) lets us see what labs can't:

Labs tell us chemistry. Imaging shows us structure. Combined? That's precision medicine.
When we combine imaging and labs, we move from guessing to seeing.
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01/12/2026

The four pillars of healthspan aren't complicated. But most people optimize the wrong things. Meaningful relationships, community, and purpose aren't "nice to have", they're biological necessities. These four pillars compound over time. Small, consistent optimizations in each area create exponential returns in healthspan. You don't need to be perfect. You need to be consistent.
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01/09/2026

We ranked 13 popular longevity supplements from Strong to Avoid. Some might surprise you. Test what you can measure. Follow evidence, not trends. And anything marketed as "anti-aging" goes straight to avoid.
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01/08/2026

Matt Kaeberlein and Dr. Nicki Byrne react to the 2025 USDA Dietary Guidelines.

Overall?
We're excited. These guidelines align with a lot of what we teach at Optispan: whole foods, adequate protein, minimal added sugars, and healthy fats.
For a population-level recommendation, this is a solid step in the right direction.
Progress, not perfection.
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If you're feeling behind because you haven't "transformed" in week one, you're actually right on schedule. What matters ...
01/07/2026

If you're feeling behind because you haven't "transformed" in week one, you're actually right on schedule. What matters most isn't when you start, it's whether your approach is built to last. New Year's resolutions are tough, but you're overthinking it. Skip the extremes. Focus on what compounds.

01/06/2026

ApoB is one of the most important markers for cardiovascular risk, yet it’s still unfamiliar to many people outside academic medicine.

Medical Director Dr. Nicki Byrne is here to explain what apoB is, what it measures, and why it provides clearer insight than traditional cholesterol numbers alone.

Understanding risk is the first step toward improving long-term health.
Precision matters in longevity science.
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01/06/2026

OMAD isn't always the metabolic optimization people think it is. One Meal A Day has become popular in longevity circles. The theory sounds compelling: extended fasting, autophagy activation, metabolic efficiency. But extreme fasting protocols don't work for everyone. Extreme protocols aren't universally optimal. What matters is finding what works for YOUR biology. This is why we test biomarkers before and during any intervention. If you're measuring, your body will tell you if a protocol is helping or harming.
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Optispan presents: Biomarker Highlights! This biomarker information was made for Longevity Texts, a partnership between ...
11/12/2025

Optispan presents: Biomarker Highlights! This biomarker information was made for Longevity Texts, a partnership between Optispan and .texts to provide consistent, actionable longevity advice.

Today’s biomarker: NMR Lipid Testing (Nuclear Magnetic Resonance), an advanced cholesterol test.

Optispan presents: Biomarker Highlights! This biomarker information was made for Longevity Texts, a partnership between ...
11/05/2025

Optispan presents: Biomarker Highlights! This biomarker information was made for Longevity Texts, a partnership between Optispan and .texts to provide consistent, actionable longevity advice.

Today’s biomarker: Apolipoprotein B, a blood biomarker that can indicate one’s risk of heart disease.

Interviewing a special member of the Dog Aging Project today - stay tuned for this episode of the Optispan Podcast!Happy...
10/31/2025

Interviewing a special member of the Dog Aging Project today - stay tuned for this episode of the Optispan Podcast!

Happy Halloween from the Optispan team! 🎃🐾

In an interview with the Lifespan Research Institute, Optispan CEO  provided his perspective on the recent incident at R...
10/29/2025

In an interview with the Lifespan Research Institute, Optispan CEO provided his perspective on the recent incident at RAADFEST 2025, where several people were hospitalized and two were in critical condition after receiving peptide injections from a vendor.

For this interview question, he gives his thoughts on the current regulations in the longevity community: where there could be more, and where there could be less.

Find the full article here -> https://www.lifespan.io/news/two-people-almost-died-at-raadfest-we-went-to-the-experts/

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