12/16/2025
Perimenopause significantly drains NAD+ (Nicotinamide Adenine Dinucleotide) levels, linked to declining estrogen, causing cellular aging, extreme fatigue, brain fog, energy crashes, mood swings and much more because NAD+ is crucial for energy production, DNA repair and hormone balance, with lower levels impacting cellular function and intensifying menopause symptoms. Increase NAD+ through precursors or lifestyle changes can help counteract these effects, support energy and overall well-being during this transition.
🗂️Why NAD+ Levels Drop in Perimenopause:
📑Hormonal Decline: Falling estrogen levels directly correlate with a rapid decrease in NAD+.
📑Cellular Aging: Lower NAD+ accelerates the aging process at a cellular level.
📑Hormone Pathways: NAD+ supports metabolic and hormonal pathways, so declining levels disrupt estrogen, progesterone, and testosterone regulation.
🗂️Symptoms of Low NAD+ Levels During Perimenopause:
📑Sudden, crashing fatigue
📑Brain fog, forgetfulness, and difficulty concentrating
📑Irritability, anxiety and mood swings
📑Afternoon energy crashes
📑Difficulty with motivation of feeling overwhelmed constantly
📑Poor sleep quality, including night sweats
Check out the comments section for an extensive list of how to boost NAD+ levels naturally and get your life back!