01/31/2026
Classic Causes of Cardiomyopathy. Afterall 80% of diagnosis is based on a patient's history. The more you know, the more you can show.
🧠 Mnemonic: “ABCC VIP”
• Alcohol
• Beri-beri (B1 deficiency)
• Coxsackie B (viral myocarditis)
• Co***ne
• Viral myocarditis
• Iron overload (hemochromatosis)
• Pregnancy (peripartum)
(+ Doxorubicin/Adriamycin)
Complications
⚠️ Mural thrombus + arrhythmias → emboli / sudden death
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2) Hypertrophic Cardiomyopathy (HCM) = THICK + TIGHT
✅ Problem: diastolic dysfunction (↓ filling)
✅ Heart: asymmetric septal hypertrophy
✅ Genetic: AD mutation (sarcomere proteins)
Key pathology
🔬 Myofiber disarray
High-yield danger
⚠️ Sudden death in young athletes
⚠️ Can cause LV outflow obstruction (septum blocks exit)
🧠 Mnemonic:
“HCM = Huge Septum = Hard to Fill”
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3) Restrictive Cardiomyopathy (RCM) = STIFF
✅ Problem: very poor filling (diastolic dysfunction)
✅ Heart size: ventricles NOT dilated (often normal)
✅ Cause: infiltration / fibrosis
Causes (must know)
🧠 Mnemonic: “ASSEL”
• Amyloidosis
• Sarcoidosis
• Scleroderma / fibrosis
• Endomyocardial fibroelastosis
• Löffler endocarditis
🧠 Easy line:
“Restrictive = Stiff heart from Stuff inside.”
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4) Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) = FATTY RV
✅ Problem: arrhythmias (esp VT)
✅ Cause: AD mutation in desmosomes
✅ Pathology: fatty infiltration of myocardium
✅ Mostly affects Right ventricle
🧠 Mnemonic:
“ARVC = Arrhythmia + RV replaced by fat”
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🔥 One-line comparison (exam gold)
✅ DCM: BIG + Weak → ↓EF (systolic)
✅ HCM: THICK + Tight → sudden death (diastolic ± obstruction)
✅ RCM: STIFF → can’t fill (diastolic)
✅ ARVC: FATTY RV → ventricular arrhythmias
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