11/24/2025
Chronic fatigue in ME/CFS isn’t a lack of willpower — it’s a metabolic shutdown.
Mitochondria slow ATP output, the vagus nerve loses its brake pedal, and the neuroimmune system amplifies every stress input.
That’s why even small efforts trigger PEM and days-long recovery.
This isn’t “just fatigue.” It’s a whole-body traffic jam.
Optimizing health by supporting natural healing through functional medicine.