WashU Medicine Knight ADRC

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The Washington University Knight ADRC is one of around 30 centers funded or otherwise supported by the National Institute on Aging with the collective aim of facilitating advanced research on Alzheimer Disease.

Novel markers of brain blood flow and oxygenation may offer early clues to Alzheimer’s risk
02/25/2026

Novel markers of brain blood flow and oxygenation may offer early clues to Alzheimer’s risk

Subtle changes in how blood flows through the brain and how brain tissue uses oxygen may be closely linked to Alzheimer’s disease risk, according to new research from the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of...

Fiber implant sheds new light on Alzheimer’s disease progression
02/24/2026

Fiber implant sheds new light on Alzheimer’s disease progression

Researchers at Washington University in St. Louis have a federal grant to develop a fiber-based, deep-brain interface to study the relationship between neurovascular dysfunction and memory loss in Alzheimer’s disease.

Alzheimer’s may begin with a silent drop in brain blood flow
02/24/2026

Alzheimer’s may begin with a silent drop in brain blood flow

Subtle changes in brain blood flow and oxygen use are closely linked to hallmark signs of Alzheimer’s, including amyloid plaques and memory-related brain shrinkage. Simple, noninvasive scans may one day help spot risk earlier—by looking at the brain’s vascular health, not just its plaques.

$80 million supports research into exceptional longevity
02/23/2026

$80 million supports research into exceptional longevity

WashU Medicine researchers have received a grant from the National Institutes of Health (NIH) to continue a study of families with a history of extreme longevity, seeking genetic clues to healthy aging.

Blood test 'clocks' predict when Alzheimer’s symptoms will start
02/20/2026

Blood test 'clocks' predict when Alzheimer’s symptoms will start

WashU Medicine researchers have developed a method to predict when someone is likely to develop symptoms of Alzheimer’s disease using a single blood test.

Researchers identify promising Alzheimer's disease drug target
02/13/2026

Researchers identify promising Alzheimer's disease drug target

Indiana University School of Medicine scientists have identified a promising drug target for Alzheimer's disease. The team found that removing an enzyme from neurons in the brain substantially reduces amyloid plaques—a hallmark characteristic of the disease—and may provide further resilience aga...

Common Anti-Seizure Drug Prevents Alzheimer’s Plaques from Forming - News Center
02/13/2026

Common Anti-Seizure Drug Prevents Alzheimer’s Plaques from Forming - News Center

Northwestern University scientists have pinpointed when and where toxic proteins accumulate within the brains of Alzheimer’s patients — and discovered a decades-old Food and Drug Administration (FDA)-approved drug that can stop the accumulation process before it even begins, according to a recen...

Engineered immune cells help reduce toxic proteins in the brain
02/13/2026

Engineered immune cells help reduce toxic proteins in the brain

Researchers at WashU Medicine and Weizmann Institute of Science designed a CAR-T cell therapy that reduced amyloid beta plaques in the brains of mice, pointing to a promising new approach for Alzheimer's disease.

Only certain types of brain-training exercises reduce dementia risk, large trial reveals
02/12/2026

Only certain types of brain-training exercises reduce dementia risk, large trial reveals

A large, 20-year trial showed that speedy cognitive exercises could reduce the risk of Alzheimer's disease and other types of dementia. The question is, could these tasks be adapted into video games?

Blood Sugar Spikes After Eating May Raise Alzheimer’s Risk
02/11/2026

Blood Sugar Spikes After Eating May Raise Alzheimer’s Risk

People who have abnormally high elevations in blood sugar after meals may be at increased risk of developing Alzheimer’s disease, according to a new report. T

Scientists discover link between Alzheimer's and long COVID on MRI scans
02/11/2026

Scientists discover link between Alzheimer's and long COVID on MRI scans

Imaging findings pertaining to the size of and blood flowing to the choroid plexus may be a common denominator between the two conditions.

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