03/09/2026
Today I address one of the hottest topics trending Facebook.
A patient asked me a question recently that I did not expect.
“Doctor… do GLP-1 drugs make people less interested in everything?”
At first I laughed. It sounded like internet nonsense.
But then I started seeing the same comments everywhere.
People taking medications like Ozempic, Wegovy, and Mounjaro often report:
• Food cravings disappear
• Alcohol becomes less appealing
• Impulsive spending drops
• Some even notice a change in libido
That raises a fascinating scientific question.
These drugs clearly quiet hunger signals.
But they also act on the brain’s reward system.
So the real question becomes:
If we turn down the brain’s craving circuits… what else might get quieter?
To be clear, there is no evidence GLP-1 drugs prevent love or relationships. The metabolic benefits of these medications are profound and life-changing for many patients.
But the conversation reveals something important about modern longevity medicine.
We are getting very good at helping people live longer.
We are still learning how to make sure we don’t flatten the experience of living in the process.
I wrote a deep dive exploring the science, the internet debate, and what we actually know so far.
Read the full article here:
https://open.substack.com/pub/doctormurphy/p/ozempic-love-and-the-longevity-trade?r=599bm2&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true
Here’s to a life well lived, not just a longer one.
— Dr. Murphy
