12/15/2025
I hope everyone is safe after last week's experience with the atmospheric river events that passed through and my prayers go out to those families who experienced flooding from these weather events. Today, I wanted to share a couple of interesting articles that I came across. The first one is on the GLP-1 medications. Now many of you know I support the sustainable use of these medications for weight loss as long as the patient is still doing their part as well (prioritizing proteins, getting sufficient exercise and getting good sleep) however there has been a lot of talk about these medications potentially curing all sorts of diseases or at least putting them at bay. Many of us were awaiting the results of the Evoke trial to see if there was a benefit for treating patients with mild to moderate Alzheimer Dementia (AD). The trial, performed by Novo Nordisk (a pharmaceutical manufacturer of Ozempic and Wegovy) failed to show that these medications were helpful in stopping the progression of AD. The hope was that this medication would cross the blood brain barrier to reduce the neuro-inflammation associated with AD.
In a separate article, researchers as looking at the use of artificial sweeteners and the impact on brain health. In a recent study published in the journal, Neurology, the researchers reported a link between artificial sweeteners such as Aspartame, Saccharin, acesulame-K, erythritol, xylitol and sorbitol were linked to declines in memory as well as overall thinking skill that was "equivalent to approximately 1.6 years of brain aging."
So the story here is that don't rely on a medication to save your brain, eat real food and if you are going to indulge in a sweet, the artificial sweeteners are not your friend.
https://www.medicalnewstoday.com/articles/can-glp-1s-actually-help-treat-alzheimers-latest-trial-data -1-agonists-and-Alzheimer-s-The-Evoke-trials
https://www.medicalnewstoday.com/articles/artificial-sweeteners-and-brain-aging-what-we-know-so-far #1
In this In Conversation podcast episode, MNT discusses a study from Brazil which found links between seven artificial sweeteners and accelerated brain aging, and other possible long-term effects.