The DNA Advantage

01/09/2026

What Insulin Resistance Actually Means
Insulin resistance means that your cells (muscle, fat, and liver) don’t respond efficiently to insulin’s signal.
Normally, insulin acts like a key that opens the cell so glucose can move from the bloodstream into the cell to be used for energy.
With insulin resistance, the lock is rusty — insulin is present, but the signal doesn’t work well.
As a result:
-Glucose stays in the bloodstream longer
-More insulin is required to get the same glucose-lowering effect
Insulin Resistance vs. Type 1 Diabetes (Important Distinction)
Type 1 Diabetes
-The pancreas produces little to no insulin
-Insulin must be supplied externally (pump or injections)
-Primary issue = insulin deficiency
Insulin Resistance
-Insulin is present (endogenous or injected)
-Cells don’t respond properly
Primary issue = poor cellular response
👉 A Type 1 diabetic can absolutely have insulin resistance.
This is often called “double diabetes.”
What Insulin Resistance Looks Like in Type 1 Diabetes
For someone with Type 1, insulin resistance often shows up as:
-Needing higher insulin doses than expected
-Blood sugars that stay high despite insulin
-Delayed glucose lowering after boluses
-Higher basal needs without obvious dietary changes
-Increased post-meal spikes
-Difficulty bringing glucose down during illness, stress, or inflammation
-This is not a failure — it’s a physiological response.
Why Insulin Resistance Happens in Type 1 Diabetics
Common contributors include:
-🔥 Inflammation
-Chronic inflammation interferes with insulin signaling
-Genes like IL6 can amplify this effect
🧬 Genetics
-Variants affecting glucose transport, mitochondrial function, or methylation (like MTHFR) can reduce insulin sensitivity
🦠 Infection or Illness
-Flu, sinus infections, or chronic pathogens raise cortisol and cytokines
😰 Stress & Cortisol
-Stress hormones directly block insulin’s action
🧪 Oxidative Stress
-Mitochondrial inefficiency (ex: SOD2) reduces glucose uptake efficiency
🧈 Lipotoxicity
-High circulating fats + insulin resistance = poor glucose disposal
-Why This Matters (Especially for You)
For Type 1 diabetics, insulin resistance means:
-More insulin ≠ better control
The goal becomes improving cellular responsiveness, not just increasing insulin
This is why approaches that support:
-Inflammation balance
-Mitochondrial health
-Mineral status
-Timing of meals & insulin
-Nervous system regulation
can dramatically improve control without chasing numbers.
Key Takeaway (Simple + Honest)
-Insulin resistance is not about insulin availability — it’s about whether your cells are listening.
And for Type 1 diabetics, supporting cellular health is just as important as managing insulin delivery.

It really sucks being a type 1 diabetic. It really means training your mind and body to eat in a new way and changing your lifestyle.

01/09/2026

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01/09/2026

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A one-day event where Christians come together to gain practical tools, grow in faith, and learn how to make a lasting impact.

01/08/2026

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12/20/2025

12/15/2025

Do those mushroom things really work???
Question of the day!

I used to wonder the same thing! But let me tell you, these aren’t just any mushrooms. Rise has a blend of 7 functional mushrooms that have been used for centuries for focus, energy, immune support, and brain clarity. It’s not magic — it’s science + nature working together to support how your body already wants to feel. I started taking it and within minutes I noticed a shift in energy that wasn’t jittery. Just smooth, focused, and more 'me.

👉 Mushrooms aren’t stimulants — they’re adaptogens.

That means they don’t force your body to do anything.
They support how your body already knows how to function, especially under stress.

Here’s the science-friendly breakdown you can share:

Functional mushrooms (like Lion’s Mane, Cordyceps, Reishi, Chaga) have been studied for their impact on:

Mitochondrial energy production
Immune signaling
Stress response (HPA axis)
Inflammation modulation
They work upstream, at the cellular communication level — not like caffeine or sugar.

That’s why people often say:
“I didn’t feel a jolt… I just felt more steady.”
“My brain feels clearer.”
“I’m not crashing anymore.”
Consistency matters more than instant sensation.

💡 What’s in Rise?

According to the Frequense Product Knowledge Base, Rise contains a blend of:
Cordyceps, Reishi, King Trumpet, Shiitake, Lion’s Mane, Turkey Tail, and Chaga.
Plus a nootropic blend for brain health, clarity, and mood. It’s paired with B vitamins and 100mg of caffeine for smooth energy. Think: brain + body + mood all vibing in harmony.

I didn’t believe in ‘mushroom magic’ either… but then I tried Rise. Within 30 minutes, my brain fog lifted, my mood leveled, and I had energy without the crash. It’s not hype — it’s 7 powerful mushrooms and nootropics that support focus, mood, and mental clarity. Wanna try a 5-day sample? Just DM me "I'm Curious-Tell me more"!

It's my business to always tell people: these aren’t claims to cure anything. Frequense doesn’t make medical claims. But many of the mushrooms used in Rise have been studied for centuries and are now getting major spotlight in brain and immune health research. All I know is — it changed my mornings.

12/13/2025

Sugar alcohols — like erythritol, xylitol, sorbitol, and maltitol — are sweeteners often used in “sugar-free” or “low-carb” foods. They aren’t actually alcohol like what’s in wine or liquor; the name comes from their chemical structure. They taste sweet but don’t behave the same way in the body as regular sugar (glucose or sucrose). It is too sweet, so why use it??
Here’s what sugar alcohols typically do to a diabetic:
Raise blood sugar a little, but not a lot
Educational moment:
Sugar alcohols generally cause a smaller rise in blood sugar compared to regular sugar. However, they are not completely “free” — some can still spike glucose slightly, depending on the type used and how much is eaten.
Vary by type
Erythritol has almost no effect on blood sugar or insulin.
Xylitol and sorbitol cause a small rise in blood sugar.
Maltitol (common in “sugar-free” candies) can cause a larger blood sugar spike — closer to real sugar!
Cause digestive issues if eaten in larger amounts
Sugar alcohols can ferment in the gut and cause bloating, gas, or diarrhea. For diabetics who already have gut sensitivity (and many do), this can create extra discomfort.
Still add some calories
Even though they aren’t counted fully like regular carbs, sugar alcohols still contribute some calories — usually about half the calories of sugar.

12/11/2025

Part 2
What do the big studies say about folic acid and autism risk?
a. Periconception folic acid seems protective overall

Several well-designed cohort and case-control studies have found that when women take folic acid before conception and in early pregnancy, their children have a lower risk of ASD:

Norwegian Mother and Child Cohort (MoBa) – >85,000 pregnancies.

Taking folic acid from 4 weeks before to 8 weeks after conception was associated with a significantly reduced risk of autistic disorder in children.
JAMA Network

CHARGE study (California) – a large case–control study:

Maternal periconceptional folic acid intake ≥600 mcg/day was associated with lower odds of ASD and developmental delay vs. low intake.
PMC

Early Autism Risk Longitudinal Investigation (EARLI) – enriched-risk cohort.

Prenatal vitamin/folic acid use in the first month of pregnancy was associated with lower ASD risk and milder autism symptoms.
PubMed

2025 umbrella review (101 studies, >3 million participants)

Maternal folic acid and/or prenatal multivitamin use was associated with about a 30–34% lower risk of ASD overall.
New York Post

This is why major organizations (CDC, USPSTF, WHO, ACOG) still strongly recommend 400–800 mcg of folic acid daily for anyone who could become pregnant, starting at least 1 month before conception and continuing through the first trimester – primarily to prevent neural tube defects, with ASD risk reduction as a likely bonus.
CDC
USPSTF

12/10/2025

PART 1 of 5
Consistent, standard-dose folic acid before and in early pregnancy is associated with lower ASD risk and dramatically lower neural tube defect risk. It does not increase ASD risk at these recommended doses.
1. Folate vs folic acid vs methylfolate – quick primer
Folate is the umbrella term for vitamin B9. It includes:
Natural food folate in leafy greens, beans, liver, etc.

Synthetic forms and active forms:
Folic acid – synthetic, very stable, used in fortification & most prenatals.
5-methyltetrahydrofolate (5-MTHF or “methylfolate”) – the main active circulating form.

Folinic acid (leucovorin) – another reduced form, used medically.
In the body, folate is central to one-carbon metabolism – the pathway that supports:
DNA and RNA synthesis
DNA methylation (turning genes “on” and “off”)
Homocysteine → methionine conversion (with B12, B6, choline, etc.)

MTHFR and other folate-pathway genes control the steps that convert folic acid/folate into methylfolate. Variants like MTHFR C677T and A1298C can reduce this enzyme’s activity and make methylation more fragile.
(American Journal of Clinical Nutrition)

That’s the mechanistic link: if methylation is off, gene expression during early brain development can be altered. Autism spectrum disorder (ASD) has repeatedly been associated with disturbances in folate and methylation pathways, though it’s one piece of a very complex puzzle.