12/23/2025
A recent study published in Physics in Medicine & Biology by Xu et al. introduces a high-precision 3D fluorescence tomography system integrated with the SARRP platform to enhance preclinical radiation research.
While standard cone-beam CT provides necessary anatomical data, this fluorescence tomography module offers the functional and molecular contrast required for precise soft-tissue targeting and treatment assessment.
The research demonstrates that this integrated approach achieves sub-millimeter localization accuracy, enabling more effective biology-guided radiation therapy in complex models such as glioblastoma.
By utilizing a transportable animal bed and a self-calibrating reconstruction method, the system ensures high-fidelity imaging within existing SARRP workflows.
Read the full open-access article to discover how this advancement is redefining precision in functional image-guided research. https://iopscience.iop.org/article/10.1088/1361-6560/ae281b