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Upgrading human performance

03/12/2026

World-renowned biohacker and performance coach Ben Greenfield relies on our Notable nootropic to support focus, mental clarity, and sustained cognitive performance.

Designed with research-backed ingredients, Notable helps power productivity, motivation, and high-level thinking for those who demand more from their brain. Learn more about the science behind the formula at meetnotable. com

03/10/2026

Society has normalized aging because everyone experiences it.

But universality does not make something healthy.

If a process consistently degrades the body, increases mortality risk, and follows biological mechanisms that can potentially be measured and treated, it fits the definition of a disease.

03/09/2026

Cerebrolysin is a multimodal neuropeptide drug used to treat various neurological disorders, including stroke, traumatic brain injury (TBI), and dementia. It is a mixture of low-molecular-weight peptides and free amino acids derived from purified porcine (pig) brain proteins.

03/08/2026

The brain is one of the most important organs in the human body, and it requires a constant supply of oxygen and nutrients to function properly. This supply is delivered through blood flow to the brain, also known as cerebral circulation.

The brain receives blood mainly through two major pairs of arteries: the carotid arteries and the vertebral arteries. The carotid arteries run along the front of the neck and supply blood to the front part of the brain, while the vertebral arteries run along the back of the neck and supply blood to the back part of the brain. These arteries connect at the base of the brain to form a circular network called the Circle of Willis, which helps ensure continuous blood supply even if one pathway is partially blocked.

Proper blood flow to the brain is essential because brain cells are highly sensitive to a lack of oxygen. If blood flow stops even for a few minutes, brain cells can begin to die. Conditions such as stroke, blood clots, or blocked arteries can reduce or stop blood flow to certain parts of the brain, leading to serious health problems.

03/06/2026

In a randomized, double-blind, placebo-controlled clinical trial published in the journal *Complementary Therapies in Medicine*, researchers studied children and adolescents aged 6–14 years with ADHD. Participants received methylphenidate (20–30 mg/day) plus either Ginkgo biloba extract (80–120 mg/day) or a placebo for 6 weeks, and symptoms were evaluated using the ADHD Rating Scale-IV.

The group receiving Ginkgo biloba as an add-on treatment showed greater improvement in attention, hyperactivity, impulsivity, and overall ADHD symptoms, with 93.5% of participants achieving at least a 27% reduction in symptoms, compared with 58.6% in the placebo group receiving methylphenidate alone.

03/05/2026

If you want to enhance your focus, productivity, and overall cognitive performance, Notable offers a solution with its Notable Focus supplement.

Designed with carefully selected nootropic ingredients, it aims to support brain function, improve concentration, and help users stay mentally sharp for work, studying, or other demanding tasks.

Click the link in our bio to learn more.

03/03/2026

Ni****ne is a potent central nervous system (CNS) stimulant. Research indicates it can improve attention, working memory, and alertness in both healthy individuals and those with cognitive impairments.

It remains a highly addictive substance, primarily due to its impact on the brain's dopamine reward system.

Epidemiological data show an inverse relationship between smoking and Parkinson’s, leading researchers to study nicotine’s neuroprotective properties and its potential to reduce motor symptoms like dyskinesia.

03/01/2026

Quercetin is a plant-derived flavonoid widely studied for its antioxidant, anti-inflammatory, neuroprotective, antiviral, and senolytic properties, though its oral bioavailability is relatively low.

As a potential nootropic, it can cross the blood–brain barrier and has shown in preclinical studies the ability to support memory and learning, protect neurons from oxidative stress, and modulate pathways such as SIRT1 and Nrf2 that are involved in cellular resilience and reduced neuroinflammation, with possible relevance to neurodegenerative diseases.

Its antiviral effects appear to stem from
interfering with multiple stages of the viral life cycle, including viral entry, protease activity, and replication, with in vitro and limited in vivo evidence against viruses such as influenza, herpes simplex, and certain coronaviruses, and it has been explored as an adjunct in respiratory infections.

Additionally, quercetin is recognized for senolytic and senomorphic actions, meaning it can help selectively promote apoptosis of senescent (“zombie”) cells and suppress the pro-inflammatory SASP factors they release; these effects are sometimes enhanced when combined with dasatinib in experimental and early clinical settings for age-related conditions.

While promising, much of the strongest evidence remains preclinical, and clinical outcomes, optimal dosing, and long-term safety continue to be investigated.

02/27/2026

Cell membrane protection is fundamental to maintaining cellular integrity, resilience, and long-term health, particularly in the face of oxidative stress and environmental damage such as UV exposure.

Key nutrients like spirulina, glycine, and astaxanthin play complementary roles in strengthening this defense system.

Spirulina provides a rich source of phycocyanin and other antioxidants that help neutralize free radicals before they damage lipid membranes.

Glycine supports the synthesis of glutathione, one of the body’s most powerful intracellular antioxidants, enhancing detoxification and protecting both cellular structures and DNA.

Astaxanthin, a potent carotenoid, uniquely spans the lipid bilayer of cell membranes, stabilizing them from within while reducing inflammation and protecting against sun-induced oxidative damage.

02/25/2026

Saffron, a spice derived from the Crocus sativus flower, has been studied for its potential benefits on mood, depression, sexual function, and memory due to its active compounds like crocin and safranal.

Research suggests that saffron may help improve symptoms of mild to moderate depression by influencing serotonin levels in the brain, similar to some antidepressant medications, and it may also enhance mood and reduce anxiety. Additionally, studies indicate that saffron can support sexual function by improving libido and addressing certain antidepressant-related sexual side effects, while its antioxidant and anti-inflammatory properties may help protect brain cells and support memory and cognitive performance.

02/24/2026

Deuterium-depleted water (DDW) is water that contains a lower concentration of deuterium, a naturally occurring heavy isotope of hydrogen, compared to regular drinking water.

Normal water contains about 150 parts per million (ppm) of deuterium, while DDW typically ranges from 25–125 ppm.

It is produced through specialized filtration or distillation processes that reduce the heavy hydrogen content.

Supporters claim that DDW may help improve cellular energy production, support metabolism, enhance athletic performance, and promote overall wellness by optimizing mitochondrial function.

Some preliminary studies suggest it may play a role in reducing oxidative stress and supporting immune health; however, more large-scale human research is needed to confirm these benefits conclusively.

DDW is sometimes used in wellness and biohacking communities as part of longevity-focused lifestyles.

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Turbo Goods LLC, 100 Ashley Drive South, Suite 600
Tampa, FL
33602

Website

https://meetnotable.com/

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