10/28/2025
Dementia Risk Increases With More Psychiatric Comorbidities
September 12, 2025
New research indicates that the risk of developing dementia increases with the number of comorbid psychiatric disorders. Individuals with two psychiatric disorders are twice as likely to develop dementia, while those with three have a fourfold risk. The presence of four or more disorders elevates the risk 11-fold. Mood and anxiety disorders, in particular, pose the greatest risk, with some subgroups showing up to a 90% probability of developing dementia. The study analyzed data from 3688 adults aged 45 and older, revealing that 18% developed dementia within an average of 18 months after their first psychiatric disorder diagnosis. These findings underscore the importance of targeted dementia screening and preventive measures in patients with multiple psychiatric disorders. This study had no specific funding.
The Takeaway: Dementia risk rises with each psychiatric comorbidity, underscoring the need for targeted screening and prevention.
Comment:
What this study means is that it is crucially important to recognize and treat mental illnesses in the middle-aged and elderly for their general health benefits but also for the purpose of prevention of dementia or at least for keeping dementia at bay for as long as possible. It therefore incomprehensible to hear that some psychiatrists' offices in my community refuse to treat elderly patients beyond a certain age. It is true that some elderly patients may be beyond the reach of psychotherapy, if they are no longer cognitively intact enough, but they can often still benefit from emotional support and possibly from judiciously dosed medication for depression, anxiety and behavioral issues.