D.O. It - Medical Evaluations

03/05/2026

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02/20/2026

Massive 44-year study reveals that long-term cannabis use does not accelerate cognitive decline.

It debunks long-held myths about the drug’s impact on brain aging.

For decades, concerns over the long-term cognitive effects of cannabis have fueled public health warnings, yet a comprehensive 44-year study from Denmark is now challenging those assumptions. Researchers tracked more than 5,000 men from early adulthood into their mid-sixties, comparing intelligence scores recorded at age 20 to follow-up assessments at age 64. The results, published in the journal Brain and Behavior, found no evidence that cannabis use accelerates cognitive decline. In a surprising twist, those with a history of use actually showed a marginally smaller decrease in IQ points—approximately 1.3 points less—than their non-using counterparts, effectively questioning the notion that the drug inevitably impairs long-term mental acuity.

While the findings are striking, experts note that lifestyle factors and 'cognitive reserve' may play a significant role in these outcomes. The study revealed that cannabis users in this cohort often possessed higher baseline IQs and education levels, which are known to influence cognitive resilience. Crucially, the researchers discovered that neither the frequency of use nor the age at which an individual started using the substance significantly impacted their intelligence later in life. Although the study was limited to men and relied on self-reported data, it provides some of the most robust longitudinal evidence to date that past cannabis use does not inherently doom the aging brain to a faster decline.

source: Christensen, T. W., Mortensen, E. L., & Osler, M.. Cannabis use and change in intelligence from age 20 to 64: A 44-year follow-up of 5,162 Danish men. Brain and Behavior.

02/13/2026

01/27/2026

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04/17/2025

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04/17/2025

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04/04/2025

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02/28/2025

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