Systematic Bioengineering Laboratory

Systematic Bioengineering Laboratory Bridging the gap between biological and engineering paradigms

[Happy Holidays] Thanks, Lilly, for the thoughtful gift that kicked off the holiday season.
12/12/2025

[Happy Holidays] Thanks, Lilly, for the thoughtful gift that kicked off the holiday season.

[IEEE NANOMED2025] What a wonderful gathering with the team! So glad to learn about the latest research of Hui! A massiv...
12/05/2025

[IEEE NANOMED2025] What a wonderful gathering with the team! So glad to learn about the latest research of Hui! A massive thank you to Yongliang for hosting us and showing off that absolutely beautiful view in Rosewood. 🏙️ It was incredibly thoughtful for Luyi to snag that abalone to-go for Shue. And Eric, I hope you enjoyed every bite of the food—but let's all keep our fingers crossed you aren't picking up too much weight! 😉 Cheers, team!

[Cancer Immunotherapy] Lilly's microbial product cocktail (MPC) cancer immunotherapy was published in Nature Communicati...
12/03/2025

[Cancer Immunotherapy] Lilly's microbial product cocktail (MPC) cancer immunotherapy was published in Nature Communications yesterday. In this work, Lilly and Sijia demonstrate the use of microbial products for cancer immunotherapy, showing that the performance is significantly better than the gold standard immunotherapy in bladder cancer. This work enables a new category of immunotherapy module. Congrats!

https://www.nature.com/articles/s41467-025-66238-1
https://rdcu.be/eSKbz

[ACS Nano] Lilly's work on personalized prognosis of bladder cancer is published in ACS Nano today. In this project, Li...
10/30/2025

[ACS Nano] Lilly's work on personalized prognosis of bladder cancer is published in ACS Nano today. In this project, Lilly and Mona developed an organoid biosensing platform for evaluating chemoresistance and chemo-induced invasion of bladder cancer patients using samples obtained from TURBT. Congrats!

https://pubs.acs.org/doi/full/10.1021/acsnano.5c09883

Great catching up with Lilly and Gary in Southern California over the weekend!
10/14/2025

Great catching up with Lilly and Gary in Southern California over the weekend!

{AMP Scholar] Ryan is accepted as an NSF AdvancingMaster’s Program scholar. Congrats!
10/06/2025

{AMP Scholar] Ryan is accepted as an NSF Advancing
Master’s Program scholar. Congrats!

[Prof. Zhang] It was wonderful to have Prof Donna Zhang from UF Scripp visiting us at Penn State.
10/04/2025

[Prof. Zhang] It was wonderful to have Prof Donna Zhang from UF Scripp visiting us at Penn State.

[One Health Microbiome Center] Chriss gave a wonderful presentation on her single cell bloodstream infection diagnostic ...
09/26/2025

[One Health Microbiome Center] Chriss gave a wonderful presentation on her single cell bloodstream infection diagnostic system in the One Health Microbiome Center today. Great job Chriss!

[Cancer Research Day] Mona’s abstract has been accepted for an oral presentation at Penn State’s Cancer Research Day. In...
09/19/2025

[Cancer Research Day] Mona’s abstract has been accepted for an oral presentation at Penn State’s Cancer Research Day. In this project, she developed a novel assay for evaluating bladder cancer invasiveness, complementing conventional clinical pathology. Congratulations!

[Graduation] Jody will receive his MS degree this week. At SBL, Jody developed a machine learning workflow for classifyi...
08/15/2025

[Graduation] Jody will receive his MS degree this week. At SBL, Jody developed a machine learning workflow for classifying cancer-associated macrophages. He is going to join the MBA program at Penn State Smeal College of Business. Congrats!

[Graduation] Congratulations to Tianbao, Samara, Malavika, and Raghad, who will graduate this weekend. Thanks to Raghad ...
05/10/2025

[Graduation] Congratulations to Tianbao, Samara, Malavika, and Raghad, who will graduate this weekend. Thanks to Raghad for the flower. Good luck, everyone!

[AI drug development] In this work, we team up with Prof. Medina's lab to develop an AI-guided workflow to identify pote...
04/25/2025

[AI drug development] In this work, we team up with Prof. Medina's lab to develop an AI-guided workflow to identify potent anti-TB peptides. The study, titled "Lead Informed Artificial Intelligence Mining of Antitubercular Host Defense Peptides", is accepted to Biomacromolecules. Congrats to Lilly and other team members!

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