11/07/2025
The White House announced agreements with Eli Lilly and Novo Nordisk that will change how patients access and afford GLP-1 medications.
Four Pathways for Patient Access:
1.TrumpRx.gov (Launching Jan 2026) This will be a government-run, direct-to-consumer cash-pay website.
- Injectables (Wegovy/Zepbound): Starting at ~$350/month, trending down to $245/month over two years.
- Oral GLP-1s (once approved): Starting doses will be priced around $150/month.
2. Medicare Coverage (Starting Mid-2026) For the first time, Medicare will cover these drugs for obesity through a CMS pilot program. This is an amazing milestone that we’ve all been waiting for.
- Patient Cost: A flat $50/month co-pay.
- Program Cost: Medicare will pay a rate of $245/month.
- Who Is Eligible? The pilot will target higher-risk beneficiaries, initially about 10% of the Medicare population. The criteria will be narrower than the FDA label, focusing on patients with:
- BMI >27 with prediabetes or established cardiovascular disease.
- BMI >30 with uncontrolled hypertension, kidney disease, or heart failure.
- BMI >35 (severe obesity).
3. Medicaid Coverage
- States will have the option to get the same low price of $245/month for GLP-1s for all covered uses.
4. LillyDirect (New Prices Available Very Soon)
- As a separate cash-pay option, Lilly has lowered its price for Zepbound to $299/month for the lowest dose (up to $449/month for higher doses). This is an immediate option for those without coverage.
- Zepbound will be available in a new multi-dose pen so perhaps this will replace the vials and make it easier for patients to administer. (Awaiting FDA approval)
Pipeline & Regulatory Updates:
Fast-Tracking Oral GLP-1s: The FDA has granted priority review vouchers to speed up the review process for oral Wegovy and Lilly’s orforglipron, shortening approval timelines.
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